There are 7 ways to get from Prague to Neu-Isenburg by subway, plane, bus, train, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Václav Havel Airport Prague, fly
best- Take the subway from Staroměstská to Nádraží Veleslavínsubway
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
4h 4m€70–159Bus
cheapest- Take the bus from Praha, ÚAN Florenc to Frankfurt Central Train Stationbus RegioJet 540
7h 40m€32–62Train via Dresden
- Take the train from Praha-Holesovice to Dresden Hbftrain Rj
- Take the train from Dresden Hauptbahnhof to Frankfurttrain 50
7h 57m€51–143Night train
- Take the night train from Praha Hlavni Nadrazi to Frankfurt(Main)Suednighttrain En
9h 51m€130–179Train to Dresden Airport, fly
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
5h 30m€150–335Train
- Take the train from Praha Hlavni Nadrazi to Frankfurt(Main)Suedtrain Ec
9h 51m€117–150Drive 505.1 km
- Drive from Prague to Neu-Isenburgcar 505.1 km
4h 15m€76–110
Prague to Neu-Isenburg by bus
Questions & Answers
The cheapest way to get from Prague to Neu-Isenburg is to bus which costs €30 - €65 and takes 7h 40m.
The fastest way to get from Prague to Neu-Isenburg is to subway and fly which takes 4h 4m and costs €70 - €160.
No, there is no direct bus from Prague to Neu-Isenburg. However, there are services departing from Praha, ÚAN Florenc and arriving at Neu-Isenburg Isenburgzentrum Süd via Frankfurt central train station and Frankfurt. The journey, including transfers, takes approximately 7h 40m.
No, there is no direct train from Prague to Neu-Isenburg. However, there are services departing from Praha-Holesovice and arriving at Frankfurt via Dresden Hauptbahnhof and Frankfurt. The journey, including transfers, takes approximately 7h 57m.
The distance between Prague and Neu-Isenburg is 434 km. The road distance is 505.1 km.
The best way to get from Prague to Neu-Isenburg without a car is to bus which takes 7h 40m and costs €30 - €65.
It takes approximately 4h 4m to get from Prague to Neu-Isenburg, including transfers.
Prague to Neu-Isenburg bus services, operated by RegioJet, depart from Praha, ÚAN Florenc station.
Prague to Neu-Isenburg train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
The best way to get from Prague to Neu-Isenburg is to bus which takes 7h 40m and costs €30 - €65. Alternatively, you can train via Dresden, which costs €50 - €150 and takes 7h 57m.
What companies run services between Prague, Czechia and Neu-Isenburg, Germany?
RegioJet operates a bus from Praha, ÚAN Florenc to Frankfurt Central Train Station once daily. Tickets cost €25–40 and the journey takes 6h 25m. Alternatively, you can take a train from Praha-Holesovice to Frankfurt via Dresden Hauptbahnhof, Frankfurt, and Frankfurt in around 7h 57m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–270
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- €60–230
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–270
Flights from Dresden Airport to Frankfurt via Munich
- Ave. Duration
- 2h 52m
- When
- Monday to Saturday
- Estimated price
- €120–270
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €65–150
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €80–270
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid.cz
Subway from Staroměstská to Nádraží Veleslavín
- Ave. Duration
- 9 min
- Frequency
- Every 10 minutes
- Estimated price
- €1–2
- Website
- https://pid.cz/en/
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Every 4 hours
- Estimated price
- €20–45
- Website
- https://www.cd.cz/en/default.htm
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- €30–45
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 18m
- Frequency
- 6 times a week
- Estimated price
- €35–50
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Frankfurt(Main)Sued
- Ave. Duration
- 9h 4m
- Frequency
- 5 times a week
- Estimated price
- €110–150
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Dresden Hauptbahnhof to Frankfurt
- Ave. Duration
- 4h 26m
- Frequency
- Every 3 hours
- Estimated price
- €28–90
- Website
- https://int.bahn.de/en
Night train from Praha Hlavni Nadrazi to Frankfurt(Main)Sued
- Ave. Duration
- 9h 4m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.oebb.at/en/
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Praha, ÚAN Florenc to Frankfurt Central Train Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- €25–40
- Website
- https://regiojet.com/
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More Questions & Answers
Prague to Neu-Isenburg bus services, operated by RegioJet, arrive at Frankfurt Central Train Station.
Prague to Neu-Isenburg train services, operated by České dráhy (ČD), arrive at Dresden Hbf station.
Yes, the driving distance between Prague to Neu-Isenburg is 505 km. It takes approximately 4h 15m to drive from Prague to Neu-Isenburg.
There are 1570+ hotels available in Neu-Isenburg.





























