There are 10 ways to get from Prague to Mytilene by plane, bus, car ferry, train, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis
best- Fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT)plane PRG - MJT
7h 24m€120–214Bus, car ferry
- Take the bus from Praha, ÚAN Florenc to Thessalonikibus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
32h 19m€220–530Train, bus, car ferry via Bucharest
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain Rj
- Take the train from Wien Hbf to Bucuresti Nordtrain 347
- Take the bus from Bucharest to Thessalonikibus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
42h 11m€426–905Drive, car ferry
- Drive from Prague to Port of Thessalonikicar
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
22h 29m€406–754Train to Vienna International Airport, fly to Mytilene International Airport Odysseas Elytis
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Mytilene International Airport Odysseas Elytis (MJT)plane VIE - MJT
8h 53m€130–359Fly Václav Havel Airport Prague to Chios Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to Chios Airport (JKH)plane PRG - JKH
- Take the ferry from Chios to Mytileneferry
11h 5m€154–250Fly Václav Havel Airport Prague to İzmir Adnan Menderes International Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to İzmir Adnan Menderes International Airport (ADB)plane PRG - ADB
- Take the ferry from Alsancak Limanı to Mytileneferry
8h 45m€138–215Bus, ferry via Sofia
- Take the bus from Praha, ÚAN Florenc to Sofiabus
- Take the bus from Sofia to Kavala Central Bus Stationbus
- Take the ferry from Kavala to Mytileneferry Bsf
32h 25m€124–230Train, bus, car ferry
- Take the train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazitrain Sc / ...
- Take the bus from Olomouc to Thessalonikibus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
35h 2m€269–577Bus, ferry
- Take the bus from Praha, ÚAN Florenc to Thessalonikibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
35h 4m€145–320
Prague to Mytilene by bus, subway, foot, and car ferry
Questions & Answers
The cheapest way to get from Prague to Mytilene is to bus and ferry via Sofia which costs €120 - €230 and takes 32h 25m.
The fastest way to get from Prague to Mytilene is to fly which takes 7h 24m and costs €120 - €220.
The distance between Prague and Mytilene is 1588 km.
The best way to get from Prague to Mytilene without a car is to bus and car ferry which takes 32h 19m and costs €220 - €550.
It takes approximately 7h 24m to get from Prague to Mytilene, including transfers.
Mytilene is 1h ahead of Prague. It is currently 12:48 AM in Prague and 1:48 AM in Mytilene.
There are 462+ hotels available in Mytilene.
What companies run services between Prague, Czechia and Mytilene, Greece?
Brussels Airlines, Aegean Airlines, and six other airlines fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT) twice daily.
- Website
- en.aegeanair.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 9h
- When
- Friday
- Estimated price
- €95–320
Flights from Vienna International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €90–360
Flights from Vienna International Airport to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €85–340
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 7h 17m
- When
- Friday and Saturday
- Estimated price
- €90–320
Flights from Václav Havel Airport Prague to Chios Airport via Thessaloniki
- Ave. Duration
- 5h 5m
- When
- Monday and Sunday
- Estimated price
- €70–220
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport via Athens
- Ave. Duration
- 6h
- When
- Friday
- Estimated price
- €100–330
- Website
- skyexpress.gr
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- €75–320
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 5h 30m
- When
- Saturday
- Estimated price
- €85–310
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 9h 42m
- When
- Every day
- Estimated price
- €85–310
Flights from Václav Havel Airport Prague to Chios Airport via Samos
- Ave. Duration
- 4h 35m
- When
- Monday and Thursday
- Estimated price
- €70–220
- Website
- austrian.com
Flights from Vienna International Airport to Mytilene International Airport Odysseas Elytis
- Ave. Duration
- 2h 5m
- When
- Monday
- Estimated price
- €85–340
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport via Vienna International Airport
- Ave. Duration
- 5h 10m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €70–260
- Website
- brusselsairlines.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Brussels
- Ave. Duration
- 7h 5m
- When
- Friday
- Estimated price
- €90–400
- Website
- transavia.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Skiathos
- Ave. Duration
- 4h 45m
- When
- Monday
- Estimated price
- €60–230
- Website
- tui.nl
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Samos
- Ave. Duration
- 7h 35m
- When
- Tuesday
- Estimated price
- €70–220
- Website
- olympicair.com
Flights from Václav Havel Airport Prague to Chios Airport via Thessaloniki
- Ave. Duration
- 5h 5m
- When
- Monday and Sunday
- Estimated price
- €70–220
- Website
- smartwings.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport
- Ave. Duration
- 2h 35m
- When
- Monday and Thursday
- Estimated price
- €60–180
- Website
- sunexpress.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport
- Ave. Duration
- 2h 35m
- When
- Thursday
- Estimated price
- €70–260
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- https://www.cd.cz/en/default.htm
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- 4 times a day
- Estimated price
- €20–35
- Website
- https://regiojet.com/
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 19m
- Frequency
- Every 2 hours
- Estimated price
- €12–21
- Website
- https://regiojet.com/
Train from Wien Hbf to Bucuresti Nord
- Ave. Duration
- 17h 30m
- Frequency
- Once daily
- Estimated price
- €220–400
- Website
- https://www.oebb.at/en/
- Phone
- +420 220 311 700
- info@le.cz
- Website
- leoexpress.com
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 25m
- Frequency
- Every 3 hours
- Estimated price
- €9–17
- Website
- https://www.leoexpress.com/en
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 33m
- Frequency
- Every 3 hours
- Estimated price
- €50–90
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +30 210 92 33 33
- info@koronatravel.gr
- Website
- koronatravel.gr
Bus from Praha, ÚAN Florenc to Thessaloniki
- Ave. Duration
- 23h 50m
- Frequency
- Once a week
- Estimated price
- €90
- Schedules at
- koronatravel.gr
Bus from Olomouc to Thessaloniki
- Ave. Duration
- 23h 51m
- Frequency
- On demand
- Estimated price
- €120
- Schedules at
- koronatravel.gr
- Phone
- +30-2310540970
- info@simeonidistours.gr
- Website
- simeonidistours.gr
Bus from Praha, ÚAN Florenc to Thessaloniki
- Ave. Duration
- 30h
- Frequency
- Once a week
- Estimated price
- €80–160
- Schedules at
- simeonidistours.gr
Bus from Bucharest to Thessaloniki
- Ave. Duration
- 9h 37m
- Frequency
- Twice a week
- Estimated price
- €45–70
- Schedules at
- simeonidistours.gr
- Phone
- +359 88 949 0000
- office@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Praha, ÚAN Florenc to Sofia
- Ave. Duration
- 17h 6m
- Frequency
- Once a week
- Estimated price
- €45–70
- Website
- https://union-ivkoni.com/en
- Phone
- +359 894 77 44 02
- office@kaleiatravel.com
- Website
- kaleiatravel.com
Bus from Sofia to Kavala Central Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- https://en.kaleiatravel.com/
- Phone
- +30 210 710 7 710
- reservations.dpt@seajets.gr
- Website
- seajets.com
Car ferry from Port of Thessaloniki to Mytilene
- Ave. Duration
- 7h 10m
- Frequency
- Once a week
- Estimated price
- €140–370
- Website
- https://www.seajets.com/
Ferry from Chios to Mytilene
- Ave. Duration
- 3h
- Frequency
- 6 times a week
- Estimated price
- €35–50
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €35–50
Ferry from Kavala to Mytilene
- Ave. Duration
- 9h 35m
- Frequency
- Once a week
- Estimated price
- €45–65
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €45–65
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 25m
- Frequency
- Twice a week
- Estimated price
- €17–40
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Kavala to Mytilene
- Ave. Duration
- 7h 55m
- Frequency
- Once a week
- Estimated price
- €45–110
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 9h 55m
- Frequency
- Once a week
- Estimated price
- €65–160
- Website
- https://www.bluestarferries.com/en-gb/
- Phone
- 0 232 330 89 22
- iletisim@izdeniz.com.tr
- Website
- izdeniz.com.tr
Ferry from Alsancak Limanı to Mytilene
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- €60
- Schedules at
- bilet.izdeniz.com.tr
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