There are 9 ways to get from Prague to Mytilene by plane, train, bus, car ferry, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mytilene International Airport Odysseas Elytis
best- Fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT)plane PRG - MJT
7h 24m€80–214Train, bus, car ferry via Budapest
- Take the train from Praha Hlavni Nadrazi to Budapest-Nyugatitrain Rj
- Take the bus from Budapest-Nyugati to Thessaloníkibus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
33h 18mDrive, ferry
- Drive from Prague to Port of Ayvalikcar
- Take the ferry from Port of Ayvalik to Mytileneferry
21h 24m€322–452Fly to Chios Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to Chios Airport (JKH)plane PRG - JKH
- Take the ferry from Chios to Mytileneferry
11h 5m€91–260Fly to İzmir Adnan Menderes International Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to İzmir Adnan Menderes International Airport (ADB)plane PRG - ADB
- Take the ferry from Alsancak Limanı to Mytileneferry
8h 45m€138–275Bus, ferry, car ferry
- Take the bus from Praha, ÚAN Florenc to Sofia Serdica Bus Stationbus
- Take the bus from Sofia to Kavala Central Bus Stationbus
- Take the ferry from Kavala to Port of Myrina (Limnos)ferry Bsf
- Take the car ferry from Port of Myrina to Mytilenecarferry
33h 54m€191–386Train, bus, car ferry
- Take the train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazitrain Ic
- Take the bus from Olomouc to Thessalonikibus
- Take the car ferry from Port of Thessaloniki to Mytilenecarferry
35h 9m€214–392Bus, ferry
- Take the bus from Praha, ÚAN Florenc to Thessalonikibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
35h 14m€115–206Bus, ferry via Sofia
- Take the bus from Praha, ÚAN Florenc to Sofiabus
- Take the bus from Sofia to Kavala Central Bus Stationbus
- Take the ferry from Kavala to Mytileneferry Bsf
38h 9m€163–291
Prague to Mytilene by bus, subway, foot, and ferry
Questions & Answers
The cheapest way to get from Prague to Mytilene is to bus and ferry which costs €110 - €210 and takes 35h 14m.
The fastest way to get from Prague to Mytilene is to fly which takes 7h 24m and costs €80 - €220.
The distance between Prague and Mytilene is 1588 km.
The best way to get from Prague to Mytilene without a car is to train and bus and car ferry via Budapest which takes 33h 18m and costs .
It takes approximately 7h 24m to get from Prague to Mytilene, including transfers.
Mytilene is 1h ahead of Prague. It is currently 5:29 AM in Prague and 6:29 AM in Mytilene.
There are 436+ hotels available in Mytilene.
What companies run services between Prague, Czechia and Mytilene, Greece?
Aegean Airlines, Brussels Airlines, and six other airlines fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT) twice daily.
- Website
- skyexpress.gr
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 7h 22m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 5h 30m
- When
- Saturday
- Estimated price
- €70–260
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 8h 55m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €70–250
Flights from Václav Havel Airport Prague to Chios Airport via Samos
- Ave. Duration
- 4h 35m
- When
- Monday and Thursday
- Estimated price
- €70–200
- Website
- en.aegeanair.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 5h 50m
- When
- Friday to Sunday
- Estimated price
- €75–270
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 7h 35m
- When
- Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €75–270
Flights from Václav Havel Airport Prague to Chios Airport via Thessaloniki
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- €70–200
- Website
- brusselsairlines.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Brussels
- Ave. Duration
- 7h 5m
- When
- Friday
- Estimated price
- €80–360
- Website
- transavia.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Skiathos
- Ave. Duration
- 4h 45m
- When
- Monday
- Estimated price
- €55–220
- Website
- tui.nl
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Samos
- Ave. Duration
- 7h 35m
- When
- Tuesday
- Estimated price
- €70–200
- Website
- olympicair.com
Flights from Václav Havel Airport Prague to Chios Airport via Thessaloniki
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- €70–200
- Website
- sunexpress.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport
- Ave. Duration
- 2h 35m
- When
- Thursday and Sunday
- Estimated price
- €70–210
- Website
- smartwings.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport
- Ave. Duration
- 2h 35m
- When
- Monday and Thursday
- Estimated price
- €55–190
- Website
- austrian.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport via Vienna
- Ave. Duration
- 5h 35m
- When
- Monday and Friday
- Estimated price
- €70–210
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Budapest-Nyugati
- Ave. Duration
- 6h 51m
- Frequency
- 3 times a day
- Estimated price
- €30–45
- Website
- https://www.cd.cz/en/default.htm
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €10–19
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Budapest-Nyugati
- Ave. Duration
- 6h 51m
- Frequency
- Twice daily
- Estimated price
- €127–128
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 33m
- Frequency
- Every 2 hours
- Estimated price
- €45–65
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 19m
- Frequency
- Hourly
- Estimated price
- €9–18
- Website
- https://regiojet.com/
- Phone
- +420 220 311 700
- info@le.cz
- Website
- leoexpress.com
Train from Praha Hlavni Nadrazi to Olomouc Hlavni Nadrazi
- Ave. Duration
- 2h 23m
- Frequency
- Every 3 hours
- Estimated price
- €11–27
- Website
- https://www.leoexpress.com/en
- Phone
- +381 011 7614787
- fptravelpatrikalos@gmail.com
- Website
- fptravelpatrikalos.rs
Bus from Budapest-Nyugati to Thessaloníki
- Ave. Duration
- 17h 5m
- Frequency
- Twice a week
- Schedules at
- fptravelpatrikalos.rs
- Phone
- +359 700 20 544
- Website
- ardatur.bg
Bus from Praha, ÚAN Florenc to Sofia Serdica Bus Station
- Ave. Duration
- 19h 25m
- Frequency
- Once daily
- Estimated price
- €65–95
- Website
- https://ardatur.bg/en/
- Phone
- +359-887-208-506
- racic_bg@yahoo.com
- Website
- racicbg.com
Bus from Praha, ÚAN Florenc to Sofia Serdica Bus Station
- Ave. Duration
- 18h
- Frequency
- 4 times a week
- Estimated price
- €70–90
- Website
- https://www.racicbg.com/bg/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Praha, ÚAN Florenc to Sofia Serdica Bus Station
- Ave. Duration
- 17h 6m
- Frequency
- Once a week
- Estimated price
- €50–75
- Website
- https://union-ivkoni.com/en
- Phone
- +359 0885700870
- support@citylines.eu
- Website
- citylines.eu
Bus from Praha, ÚAN Florenc to Sofia Serdica Bus Station
- Ave. Duration
- 18h 30m
- Frequency
- Once a week
- Estimated price
- €70–100
- Website
- https://citylines.eu/
- Phone
- +359 894 77 44 02
- office@kaleiatravel.com
- Website
- kaleiatravel.com
Bus from Sofia to Kavala Central Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- https://en.kaleiatravel.com/
- Phone
- +30 210 92 33 33
- info@koronatravel.gr
- Website
- koronatravel.gr
Bus from Olomouc to Thessaloniki
- Ave. Duration
- 23h 51m
- Frequency
- On demand
- Estimated price
- €120
- Schedules at
- koronatravel.gr
Bus from Praha, ÚAN Florenc to Thessaloniki
- Ave. Duration
- 23h 50m
- Frequency
- Once a week
- Estimated price
- €90
- Schedules at
- koronatravel.gr
- Phone
- +30-2310540970
- info@simeonidistours.gr
- Website
- simeonidistours.gr
Bus from Praha, ÚAN Florenc to Thessaloniki
- Ave. Duration
- 30h
- Frequency
- Once a week
- Estimated price
- €80–170
- Schedules at
- simeonidistours.gr
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, ÚAN Florenc to Sofia
- Ave. Duration
- 22h 50m
- Frequency
- 3 times a week
- Estimated price
- €100–150
- Website
- https://www.flixbus.co.uk
- Phone
- +30 210 710 7 710
- reservations.dpt@seajets.gr
- Website
- seajets.com
Car ferry from Port of Thessaloniki to Mytilene
- Ave. Duration
- 7h 10m
- Frequency
- Once a week
- Estimated price
- €85–210
- Website
- https://www.seajets.com/
- Deck Fare Economy
- €85–130
- Deck Fare Economy & Car less than 4.25m
- €150–210
Car ferry from Port of Myrina to Mytilene
- Ave. Duration
- 2h 50m
- Frequency
- Once a week
- Estimated price
- €65–160
- Website
- https://www.seajets.com/
- Deck Fare Economy
- €65–90
- Deck Fare Economy & Car less than 4.25m
- €110–160
- Phone
- +30 694 415 6070
- info@makritravel.com
- Website
- makritravel.com
Ferry from Port of Ayvalik to Mytilene
- Ave. Duration
- 1h
- Frequency
- 3 times a week
- Estimated price
- €30
- Website
- https://www.makritravel.com/
Ferry from Chios to Mytilene
- Ave. Duration
- 3h
- Frequency
- 5 times a week
- Estimated price
- €35–50
- Website
- https://www.hellenicseaways.gr/en-gb
- Airplane Type Seats
- €35–50
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 15m
- Frequency
- Twice a week
- Estimated price
- €14–20
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Kavala to Port of Myrina (Limnos)
- Ave. Duration
- 3h 15m
- Frequency
- Once a week
- Estimated price
- €26–80
- Website
- https://www.bluestarferries.com/en-gb/
- Economy
- €26–40
- 2 Bed Inside Cabin
- €55–70
- 4 Bed Outside Cabin
- €45–60
- 2 Bed Lux Cabin
- €65–80
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Once a week
- Estimated price
- €35–45
- Website
- https://www.bluestarferries.com/en-gb/
Ferry from Kavala to Mytilene
- Ave. Duration
- 7h 55m
- Frequency
- Once a week
- Estimated price
- €30–100
- Website
- https://www.bluestarferries.com/en-gb/
- Economy
- €30–50
- 2 Bed Inside Cabin
- €65–80
- 4 Bed Outside Cabin
- €60–70
- 2 Bed Lux Cabin
- €80–100
- Phone
- 0 232 330 89 22
- iletisim@izdeniz.com.tr
- Website
- izdeniz.com.tr
Ferry from Alsancak Limanı to Mytilene
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- €60
- Schedules at
- bilet.izdeniz.com.tr
Want to know more about travelling around Greece
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