There are 8 ways to get from Prague to Mendrisio by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Milano Malpensa Airport, train
best- Fly from Václav Havel Airport Prague (PRG) to Milano Malpensa Airport (MXP)plane PRG - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 25mCHF 54–158Bus
cheapest- Take the bus from Praha, Hlavní Nádraží to Comobus N1308
12h 51mCHF 40–145Train
- Take the train from Praha Hlavni Nadrazi to Zuerich Hbtrain Ec
- Take the train from Zürich HB to Bellinzonatrain Ic2 / ...
- Take the train from Bellinzona to Mendrisiotrain S10 / ...
17h 20mCHF 197–279Drive 785.3 km
- Drive from Prague to Mendrisiocar 785.3 km
8hCHF 126–181Fly to Milan Linate Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Milan Linate Airport (LIN)plane PRG - LIN
- Take the train from Monza to Mendrisiotrain
7h 28mCHF 87–212Fly to Il Caravaggio International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Il Caravaggio International Airport (BGY)plane PRG - BGY
- Take the train from Milano Centrale to Mendrisiotrain
6h 23mCHF 50–204Fly to Zurich Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Zurich Airport (ZRH)plane PRG - ZRH
- Take the train from Zürich HB to Luganotrain
6h 49mCHF 106–267Bus via Sankt Gallen
- Take the bus from Praha, ÚAN Florenc to Sankt Gallenbus
- Take the bus from St. Gallen to Chiassobus
14h 55mCHF 103–105
Prague to Mendrisio by bus and train
Questions & Answers
The cheapest way to get from Prague to Mendrisio is to bus which costs SFr 40 - SFr 150 and takes 12h 51m.
The fastest way to get from Prague to Mendrisio is to fly and train which takes 5h 25m and costs SFr 50 - SFr 160.
No, there is no direct bus from Prague to Mendrisio. However, there are services departing from Praha, ÚAN Florenc and arriving at Mendrisio, Autosilo via St. Gallen and Chiasso, Stazione. The journey, including transfers, takes approximately 14h 55m.
No, there is no direct train from Prague to Mendrisio. However, there are services departing from Praha Hlavni Nadrazi and arriving at Mendrisio via Zürich HB and Bellinzona. The journey, including transfers, takes approximately 17h 20m.
The distance between Prague and Mendrisio is 720 km. The road distance is 785.3 km.
The best way to get from Prague to Mendrisio without a car is to bus which takes 12h 51m and costs SFr 40 - SFr 150.
It takes approximately 5h 25m to get from Prague to Mendrisio, including transfers.
Prague to Mendrisio bus services, operated by Nobless Line, depart from Praha, ÚAN Florenc station.
Prague to Mendrisio train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Mendrisio is to bus which takes 12h 51m and costs SFr 40 - SFr 150. Alternatively, you can train, which costs SFr 190 - SFr 280 and takes 17h 20m.
What companies run services between Prague, Czechia and Mendrisio, Switzerland?
FlixBus operates a bus from Praha, Hlavní Nádraží to Como once daily. Tickets cost CHF 35–95 and the journey takes 12h. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mendrisio via Zuerich Hb, Zürich HB, and Bellinzona in around 17h 20m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- CHF 55–240
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Frankfurt
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- CHF 60–260
Flights from Václav Havel Airport Prague to Milan Linate Airport via Munich
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- CHF 75–230
Flights from Václav Havel Airport Prague to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- CHF 75–300
Flights from Václav Havel Airport Prague to Zurich Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Monday to Friday
- Estimated price
- CHF 65–250
Flights from Václav Havel Airport Prague to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- CHF 65–270
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Il Caravaggio International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- CHF 40–150
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Zurich Airport
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- CHF 55–230
Flights from Václav Havel Airport Prague to Zurich Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- CHF 65–180
- Website
- ita-airways.com
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Monday and Tuesday
- Estimated price
- CHF 75–240
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Zurich Airport
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- CHF 55–230
Flights from Václav Havel Airport Prague to Milan Linate Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- CHF 75–230
Flights from Václav Havel Airport Prague to Zurich Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- CHF 65–180
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Milan Linate Airport via Vienna
- Ave. Duration
- 4h 20m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- CHF 75–280
Flights from Václav Havel Airport Prague to Zurich Airport via Vienna
- Ave. Duration
- 3h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- CHF 60–260
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Milano Malpensa Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 23–100
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Tuesday to Sunday
- Estimated price
- CHF 80–260
Flights from Václav Havel Airport Prague to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- CHF 75–230
Flights from Václav Havel Airport Prague to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Tuesday to Sunday
- Estimated price
- CHF 85–270
- Website
- condor.com
Flights from Václav Havel Airport Prague to Milano Malpensa Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Saturday and Sunday
- Estimated price
- CHF 45–110
Flights from Václav Havel Airport Prague to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Tuesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 55–150
- Website
- brusselsairlines.com
Flights from Václav Havel Airport Prague to Milan Linate Airport via Brussels
- Ave. Duration
- 5h 37m
- When
- Monday to Saturday
- Estimated price
- CHF 75–160
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
Train from Bellinzona to Mendrisio
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 2–3
- Website
- https://www.trenord.it/en/
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- https://www.trenord.it/en/
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Bellinzona
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- CHF 30–65
- Website
- https://www.sbb.ch/en
Train from Bellinzona to Mendrisio
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 11–21
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- CHF 40–75
- Website
- https://www.sbb.ch/en
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Zuerich Hb
- Ave. Duration
- 14h 34m
- Frequency
- Once daily
- Estimated price
- CHF 160–220
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 58 580 70 70
- info@sob.ch
- Website
- sob.ch
Train from Zürich HB to Bellinzona
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Schedules at
- sob.ch
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, Hlavní Nádraží to Como
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- CHF 35–95
- Website
- https://www.flixbus.co.uk
- Phone
- +420 602 333 369
- noblessline@noblessline.cz
- Website
- noblessline.cz
Bus from Praha, ÚAN Florenc to Sankt Gallen
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- CHF 81
- Schedules at
- noblessline.cz
- Phone
- +390975 343195
- info@ventrebus.com
- Website
- ventrebus.com
Bus from St. Gallen to Chiasso
- Ave. Duration
- 5h 30m
- Frequency
- Once a week
- Estimated price
- CHF 20
- Schedules at
- ventrebus.com
Want to know more about travelling around Switzerland
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More Questions & Answers
Prague to Mendrisio bus services, operated by Nobless Line, arrive at Sankt Gallen station.
Prague to Mendrisio train services, operated by ÖBB EuroCity, arrive at Zuerich Hb station.
Yes, the driving distance between Prague to Mendrisio is 785 km. It takes approximately 8h to drive from Prague to Mendrisio.
Book your Prague to Mendrisio train tickets online with Omio.
There are 4892+ hotels available in Mendrisio.





























