There are 7 ways to get from Prague to Main by subway, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Václav Havel Airport Prague, fly
best- Take the subway from Staroměstská to Nádraží Veleslavín
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)PRG - FRA
3h 59mBus
cheapest- Take the bus from Praha, Hlavní Nádraží to Mainz central train stationN1310
8h 46m€30–60Bus via Frankfurt
- Take the bus from Praha, ÚAN Florenc to Frankfurt Central Train StationRegioJet 540
7h 16m€34–55Train via Schwandorf
- Take the train from Praha Hlavni Nadrazi to SchwandorfEc
- Take the train from Schwandorf to Nürnberg Hbf
- Take the train from Nürnberg Hbf to Frankfurt41 / ...
9h 2m€94–165Drive 535.3 km
- Drive from Prague to Main535.3 km
4h 43m€82–119Train to Dresden Airport, fly
- Take the train from Praha Hlavni Nadrazi to Dresden Hbf
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)DRS - FRA
5h 38m€152–303Train
- Take the train from Praha Hlavni Nadrazi to Frankfurt(Main)SuedEc
10h 33m€105–145
Prague to Main by bus, foot, and train
Questions & Answers
The cheapest way to get from Prague to Main is to bus which costs €30 - €60 and takes 8h 46m.
The fastest way to get from Prague to Main is to drive which takes 4h 43m and costs €80 - €120.
No, there is no direct bus from Prague to Main. However, there are services departing from Praha, Hlavní Nádraží and arriving at Weisenau, Favorite-Parkhotel via Mainz, Hauptbahnhof. The journey, including transfers, takes approximately 8h 46m.
No, there is no direct train from Prague to Main. However, there are services departing from Praha Hlavni Nadrazi and arriving at Mainz, Römisches Theater via Schwandorf, Nürnberg Hbf and Frankfurt. The journey, including transfers, takes approximately 9h 2m.
The distance between Prague and Main is 447 km. The road distance is 535.3 km.
The best way to get from Prague to Main without a car is to bus via Frankfurt which takes 7h 16m and costs €30 - €55.
It takes approximately 3h 59m to get from Prague to Main, including transfers.
Prague to Main bus services, operated by FlixBus, depart from Praha, Hlavní Nádraží station.
Prague to Main train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Main is to bus via Frankfurt which takes 7h 16m and costs €30 - €55. Alternatively, you can train via Schwandorf, which costs €90 - €170 and takes 9h 2m.
What companies run services between Prague, Czechia and Main, Hesse, Germany?
RegioJet operates a bus from Praha, ÚAN Florenc to Frankfurt Central Train Station once daily. Tickets cost €25–40 and the journey takes 6h 25m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mainz, Römisches Theater via Schwandorf, Nürnberg Hbf, and Frankfurt in around 9h 2m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €65–270
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €70–280
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–320
Flights from Dresden Airport to Frankfurt via Munich
- Ave. Duration
- 2h 52m
- When
- Every day
- Estimated price
- €120–320
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €60–120
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €80–270
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid.cz
Subway from Staroměstská to Nádraží Veleslavín
- Ave. Duration
- 9 min
- Frequency
- Every 10 minutes
- Website
- https://pid.cz/en/
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 22m
- Frequency
- 5 times a day
- Estimated price
- €35–55
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Frankfurt(Main)Sued
- Ave. Duration
- 9h 4m
- Frequency
- 5 times a week
- Estimated price
- €95–140
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 14m
- Frequency
- Every 3 hours
- Estimated price
- €16–24
- Website
- https://int.bahn.de/en
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Nürnberg Hbf to Frankfurt
- Ave. Duration
- 2h 7m
- Frequency
- Hourly
- Estimated price
- €25–65
- Website
- https://int.bahn.de/en
#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 19m
- Frequency
- 5 times a day
- Estimated price
- €11–24
- Website
- https://www.cd.cz/en/default.htm
- 2nd Class
- €11–16
- 1st Class
- €18–24
- Business
- €19–21
- Phone
- +36 (1) 3 49 49 49
- info@mavcsoport.hu
- Website
- jegy.mav.hu
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 17m
- Frequency
- 5 times a week
- Estimated price
- €8–10
- Website
- https://jegy.mav.hu/
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Praha, ÚAN Florenc to Frankfurt Central Train Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- €25–40
- Website
- https://regiojet.com/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, Hlavní Nádraží to Mainz central train station
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a week
- Estimated price
- €30–60
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Prague to Main bus services, operated by FlixBus, arrive at Mainz central train station.
Prague to Main train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Main is 535 km. It takes approximately 4h 43m to drive from Prague to Main.
Book your Prague to Main train tickets online with Omio.
There are 1119+ hotels available in Main.