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How to get fromPrague to Madridby plane, train (Renfe, Ouigo), bus, train or car

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There are 7 ways to get from Prague to Madrid by plane, train (Renfe, Ouigo), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Václav Havel Airport Prague

    best
    1. Fly from Václav Havel Airport Prague (PRG) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PRG - MAD
    5h 58m
    €65–157

  2. Train

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train Rj
    2. Take the train from Dresden Hauptbahnhof to Erfurt Hbftrain train 50 / ...
    3. Take the train from Erfurt Hbf to Strasbourg Bahnhoftrain train 82
    4. Take the train from Strasbourg Bahnhof to Lyon Part Dieutrain train 84
    5. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    6. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    23h 53m
    €230–710

  3. Bus, train

    1. Take the bus from Praha, ÚAN Florenc to Lyon Perrache Bus Stationbus bus
    2. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    3. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    25h 13m
    €144–315

  4. Drive 2,187.1 km

    1. Drive from Prague to Madridcar car 2,187.1 km
    20h 34m
    €340–491

  5. Train to Dresden Airport, fly

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane DRS - MAD
    9h 54m
    €151–473

  6. Bus via Karlsruhe

    1. Take the bus from Praha, ÚAN Florenc to Karlsruhe central train stationbus bus N1316 / ...
    2. Take the bus from Karlsruhe - Central Station South Side to Madrid - South Stationbus bus BlaBlaCar Bus
    36h 25m
    €90–218

  7. Bus

    1. Take the bus from Praha, ÚAN Florenc to Dresden central stationbus bus 060 / ...
    2. Take the bus from Dresden to Madridbus bus Kyiv-Porto
    38h 27m

Prague to Madrid by train

Calendar7Weekly Trains
Duration23h 53mAverage Duration
Ticket€230Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Madrid, Spain?

Ryanair, Smartwings, and five other airlines fly from Václav Havel Airport Prague (PRG) to Adolfo Suárez Madrid–Barajas Airport (MAD) every 4 hours. Alternatively, you can take a train from Praha-Holesovice to Madrid-Puerta de Atocha-Almudena Grandes via Dresden Hauptbahnhof, Erfurt Hbf, Strasbourg Bahnhof, Lyon Part Dieu, and Barcelona-Sants in around 23h 53m.

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