There are 7 ways to get from Prague to Lyon by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Lyon  •  4 h 47 min

  1. Fly from Prague (PRG) to Lyon (LYS) PRG - LYS

$88 - $269

Cheapest option

Bus RegioJet  •  17 h 15 min

  1. Take the bus from Praha, ÚAN Florenc to Lyon, de Perrache - Galerie A Rj

$40 - $190

5 alternative options

Fly to Geneva, train  •  7 h 22 min

  1. Fly from Prague (PRG) to Geneva (GVA) PRG - GVA
  2. Take the train from Genève to Lyon Part Dieu

$97 - $310

Train TGV  •  12 h 58 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Frankfurt(Main)Hbf Ice / ...
  3. Take the train from Frankfurt(Main)Hbf to Lyon Part Dieu Tgv

$218 - $291

Bus Tour Bus  •  16 h 35 min

  1. Take the bus from Prague to Lausanne 000259
  2. Take the bus from Lausanne to Lyon

$94 - $149

Train EuroNight  •  20 h 29 min

  1. Take the train from Praha hl.n. to Zürich HB En
  2. Take the train from Zürich HB to Genève 1 / ...
  3. Take the train from Genève to Lyon Part Dieu Tgv

$109 - $186

Drive  •  9 h 32 min

  1. Drive from Prague to Lyon 675.5 miles

$140 - $210

Questions & Answers

The cheapest way to get from Prague to Lyon is to fly which costs 1 900 Kč - 6 000 Kč and takes 4 h 47 min.

More details

The quickest way to get from Prague to Lyon is to fly which costs 1 900 Kč - 6 000 Kč and takes 4 h 47 min.

More details

Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Lyon, de Perrache - Galerie A. Services depart five times a week, and operate Monday, Tuesday, Wednesday, Friday and Sunday. The journey takes approximately 17 h 15 min.

More details

No, there is no direct train from Prague to Lyon. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Lyon Part Dieu via Nürnberg Hbf and Frankfurt(Main)Hbf. The journey, including transfers, takes approximately 12 h 58 min.

More details

The distance between Prague and Lyon is 860 km. The road distance is 1080.8 km.

Get driving directions

The best way to get from Prague to Lyon without a car is to train which takes 12 h 58 min and costs 4 800 Kč - 6 500 Kč.

More details

It takes approximately 4 h 47 min to get from Prague to Lyon, including transfers.

More details

Prague to Lyon bus services, operated by RegioJet, depart from Praha, ÚAN Florenc station.

More details

Prague to Lyon train services, operated by Czech Railways (ČD), depart from Praha hl.n. (Autobusová St. Wilsonova) station.

More details

The best way to get from Prague to Lyon is to fly which takes 4 h 47 min and costs 1 900 Kč - 6 000 Kč. Alternatively, you can train, which costs 4 800 Kč - 6 500 Kč and takes 12 h 58 min, you could also bus, which costs 2 100 Kč - 3 400 Kč and takes 16 h 35 min.

Mode details

Map of how to get from Prague to Lyon.
Launch map view
  • Distance: 537.7 miles
  • Duration: 4 h 47 min

What companies run services between Prague, Czech Republic and Lyon, France?

Hop!, Brussels Airlines and three other airlines fly from Prague to Lyon every 4 hours. Alternatively, you can take a train from Prague to Lyon via Nürnberg ZOB, Nürnberg Hbf, and Frankfurt(Main)Hbf in around 12 h 58 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Lyon via Frankfurt
Ave. Duration
4 h
When
Every day
Estimated price
$170 - $800
Flights from Prague to Geneva via Munich
Ave. Duration
3 h 7 min
When
Every day
Estimated price
$160 - $950
Flights from Prague to Geneva via Frankfurt
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$160 - $950
Air France
Website
airfrance.com
Flights from Prague to Lyon
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$180 - $850
Flights from Prague to Geneva via Paris CDG
Ave. Duration
4 h
When
Every day
Estimated price
$130 - $490
Swiss
Website
swiss.com
Flights from Prague to Geneva
Ave. Duration
1 h 30 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $370
Flights from Prague to Geneva via Zurich
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$70 - $370
Brussels Airlines
Website
brusselsairlines.com
Flights from Prague to Lyon via Brussels
Ave. Duration
3 h 50 min
When
Monday to Saturday
Estimated price
$85 - $500
Flights from Prague to Geneva via Brussels
Ave. Duration
3 h 45 min
When
Monday to Saturday
Estimated price
$85 - $430
Hop!
Website
hop.com
Flights from Prague to Lyon
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$180 - $850
Austrian Airlines
Website
austrian.com
Flights from Prague to Lyon via Vienna
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$170 - $900
Flights from Prague to Geneva via Vienna
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$160 - $950
KLM
Website
klm.com
Flights from Prague to Lyon via Amsterdam
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$150 - $700
Train operators
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Genève to Lyon Part Dieu
Ave. Duration
2 h
Frequency
Every 4 hours
Estimated price
$30 - $50
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Zürich HB to Genève
Ave. Duration
2 h 46 min
Frequency
Hourly
Estimated price
$85 - $160
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Genève to Lyon Part Dieu
Ave. Duration
1 h 44 min
Frequency
Once daily
Estimated price
$35 - $45
Website
en.oui.sncf
2nd Class
$35 - $45
1st Class
$55 - $70
Train from Frankfurt(Main)Hbf to Lyon Part Dieu
Ave. Duration
5 h 58 min
Frequency
Twice a week
Estimated price
$130 - $160
Website
en.oui.sncf
2nd Class
$130 - $160
1st Class
$180 - $270
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 4 hours
Estimated price
$40 - $65
Website
cd.cz
EuroNight
Website
cd.cz
Train from Praha hl.n. to Zürich HB
Ave. Duration
14 h 19 min
Frequency
Once daily
Website
cd.cz
Bus operators
Tour Bus
Website
tourbus.cz
Bus from Prague to Lausanne
Ave. Duration
11 h 48 min
Frequency
3 times a week
Estimated price
$65 - $120
Schedules at
tourbus.cz
Eurolines CH
Phone
0041 (0) 844 257 224
Website
eurolines.ch
Bus from Lausanne to Lyon
Ave. Duration
3 h 30 min
Frequency
3 times a week
Estimated price
$25 - $31
Book at
eurolines.ch
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Praha, ÚAN Florenc to Lyon, de Perrache - Galerie A
Ave. Duration
17 h 15 min
Frequency
3 times a week
Estimated price
$40 - $50
Schedules at
regiojet.sk
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Prague to Lyon
Ave. Duration
17 h 30 min
Frequency
3 times a week
Estimated price
$130 - $190
Schedules at
eurolines.fr
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Lyon
Ave. Duration
19 h 30 min
Frequency
Twice a week
Estimated price
$45 - $90
Schedules at
elines.cz

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