There are 7 ways to get from Prague to Lyon by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Lyon  •  4 h 49 min

  1. Fly from Prague (PRG) to Lyon (LYS) PRG - LYS

$89 - $271

Cheapest option

Bus RegioJet  •  17 h 15 min

  1. Take the bus from Praha, ÚAN Florenc to Lyon, de Perrache - Galerie C Rj

$40 - $200

5 alternative options

Fly to Geneva, train  •  7 h 23 min

  1. Fly from Prague (PRG) to Geneva (GVA) PRG - GVA
  2. Take the train from Geneve to Lyon Part Dieu

$97 - $311

Train TGV  •  12 h 59 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Frankfurt(Main)Hbf Ice / ...
  3. Take the train from Frankfurt(Main)Hbf to Lyon Part Dieu Tgv

$235 - $299

Bus Tour Bus  •  15 h 34 min

  1. Take the bus from Prague to Lausanne 000259
  2. Take the bus from Lausanne to Lyon - Perrache Bus station Bâle Centre > Zurich > Berne > Fribourg > Lausanne > Genève - Gare routière > Lyon - Gare routière Perrache > Saint-Etienne > Clermont-Ferrand > Brive-la-Gaillarde > Bordeaux Centre > Bayonne > Saint-Sébastien > Hernani / ...

$82 - $138

Train EuroNight  •  20 h 29 min

  1. Take the train from Praha hl.n. to Zürich HB En
  2. Take the train from Zürich HB to Genève 1 / ...
  3. Take the train from Geneve to Lyon Part Dieu Tgv

$117 - $202

Drive  •  9 h 32 min

  1. Drive from Prague to Lyon 675.5 miles

$140 - $210

What companies run services between Prague, Czech Republic and Lyon, France?

Hop!, Brussels Airlines and three other airlines fly from Prague to Lyon every 4 hours. Alternatively, you can take a train from Prague to Lyon via Nürnberg ZOB, Nürnberg Hbf, and Frankfurt(Main)Hbf in around 12 h 59 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Lyon via Frankfurt
Ave. Duration
4 h
When
Every day
Estimated price
$170 - $800
Flights from Prague to Geneva via Munich
Ave. Duration
3 h 7 min
When
Every day
Estimated price
$160 - $950
Flights from Prague to Geneva via Frankfurt
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$160 - $950
Air France
Website
airfrance.com
Flights from Prague to Lyon
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$180 - $850
Flights from Prague to Geneva via Paris CDG
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$110 - $440
Swiss
Website
swiss.com
Flights from Prague to Geneva
Ave. Duration
1 h 30 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $370
Flights from Prague to Geneva via Zurich
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$70 - $370
Brussels Airlines
Website
brusselsairlines.com
Flights from Prague to Lyon via Brussels
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$85 - $500
Flights from Prague to Geneva via Brussels
Ave. Duration
3 h 45 min
When
Monday to Saturday
Estimated price
$85 - $430
Hop!
Website
hop.com
Flights from Prague to Lyon
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$180 - $850
Austrian Airlines
Website
austrian.com
Flights from Prague to Lyon via Vienna
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$170 - $900
Flights from Prague to Geneva via Vienna
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$160 - $950
KLM
Website
klm.com
Flights from Prague to Lyon via Amsterdam
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$150 - $700
Train operators
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Geneve to Lyon Part Dieu
Ave. Duration
2 h
Frequency
Every 3 hours
Estimated price
$30 - $50
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Zürich HB to Genève
Ave. Duration
2 h 46 min
Frequency
Hourly
Estimated price
$85 - $160
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Geneve to Lyon Part Dieu
Ave. Duration
1 h 44 min
Frequency
Twice daily
Estimated price
$35 - $45
Website
en.oui.sncf
2nd Class
$35 - $45
1st Class
$60 - $75
Train from Frankfurt(Main)Hbf to Lyon Part Dieu
Ave. Duration
5 h 58 min
Frequency
Once daily
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$190 - $280
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$45 - $65
Website
cd.cz
EuroNight
Website
cd.cz
Train from Praha hl.n. to Zürich HB
Ave. Duration
14 h 19 min
Frequency
Once daily
Website
cd.cz
Bus operators
Tour Bus
Website
tourbus.cz
Bus from Prague to Lausanne
Ave. Duration
11 h 48 min
Frequency
3 times a week
Estimated price
$70 - $130
Schedules at
tourbus.cz
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Lausanne to Lyon - Perrache Bus station
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$8 - $12
Website
Ouibus
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Praha, ÚAN Florenc to Lyon, de Perrache - Galerie C
Ave. Duration
17 h 15 min
Frequency
3 times a week
Estimated price
$40 - $55
Schedules at
regiojet.sk
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Prague to Lyon
Ave. Duration
17 h 30 min
Frequency
3 times a week
Estimated price
$130 - $200
Schedules at
eurolines.fr
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Lyon
Ave. Duration
19 h 30 min
Frequency
Twice a week
Estimated price
$50 - $95
Schedules at
elines.cz

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Questions & Answers

How far is it from Prague to Lyon?

The distance between Prague and Lyon is 860 km. The road distance is 1081 km.

What is the cheapest way to get from Prague to Lyon?

The cheapest way to get from Prague to Lyon is to fly which costs 1 800 Kč - 6 000 Kč and takes 4 h 49 min.

What is the fastest way to get from Prague to Lyon?

The quickest way to get from Prague to Lyon is to fly which takes 4 h 49 min and costs 1 800 Kč - 6 000 Kč.

Is there a direct train between Prague and Lyon?

No, there is no direct train from Prague to Lyon. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Lyon Part Dieu via Nürnberg Hbf and Frankfurt(Main)Hbf. The journey, including transfers, takes approximately 12 h 59 min.

Is there a direct bus between Prague and Lyon?

Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Lyon, de Perrache - Galerie C. Services depart five times a week, and operate Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. The journey takes approximately 17 h 15 min.

How long does it take to get from Prague to Lyon?

It takes approximately 4 h 49 min to get from Prague to Lyon, including transfers.