Select from 4 ways to get there

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  7 h 45 min

  1. Take the bus from Praha, ÚAN Florenc to Karlsruhe, Hbf. - Süd, am Hintereingang Rj / ...

$19 - $80

8 alternative options

Train  •  7 h 49 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Karlsruhe Hbf Ic

$103 - $146

Drive  •  4 h 39 min

  1. Drive from Prague to Karlsruhe 328.1 miles

$65 - $100

Fly Prague to Stuttgart, bus  •  7 h 11 min

  1. Fly from Prague (PRG) to Stuttgart (STR) PRG - STR
  2. Take the bus from Stuttgart to Karlsruhe

$85 - $190

Fly Prague to Frankfurt, train  •  5 h 4 min

  1. Fly from Prague (PRG) to Frankfurt (FRA) PRG - FRA
  2. Take the train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
  3. Take the train from Mannheim Hbf to Karlsruhe Hbf

$96 - $286

Bus to Dresden, fly to Stuttgart, bus  •  5 h 58 min

  1. Take the bus from Praha, ÚAN Florenc to Drážďany, Letiště
  2. Fly from Dresden (DRS) to Stuttgart (STR) DRS - STR
  3. Take the bus from Stuttgart to Karlsruhe

$59 - $225

Fly Prague to Strasbourg, train  •  6 h 3 min

  1. Fly from Prague (PRG) to Strasbourg (SXB) PRG - SXB
  2. Take the train from Strasbourg to Karlsruhe Hbf

$112 - $371

Bus to Dresden, fly to Frankfurt, train  •  5 h 56 min

  1. Take the bus from Praha, ÚAN Florenc to Drážďany, Letiště
  2. Fly from Dresden (DRS) to Frankfurt (FRA) DRS - FRA
  3. Take the train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
  4. Take the train from Mannheim Hbf to Karlsruhe Hbf

$110 - $321

Fly Prague to Zurich, train  •  7 h 50 min

  1. Fly from Prague (PRG) to Zurich (ZRH) PRG - ZRH
  2. Take the train from Zürich HB to Karlsruhe Hbf

$140 - $372

What companies run services between Prague, Czech Republic and Karlsruhe, Germany?

RegioJet operates a bus from Prague to Karlsruhe 3 times a week. Tickets cost $19 - $25 and the journey takes 7 h 45 min. Three other operators also service this route. Alternatively, you can take a train from Prague to Karlsruhe via Nürnberg ZOB and Nürnberg Hbf in around 7 h 49 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Stuttgart via Munich
Ave. Duration
3 h 37 min
When
Every day
Estimated price
$210 - $650
Flights from Prague to Stuttgart via Frankfurt
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$210 - $650
Flights from Prague to Frankfurt
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$100 - $480
Flights from Prague to Frankfurt via Munich
Ave. Duration
3 h
When
Every day
Estimated price
$100 - $480
Flights from Dresden to Stuttgart via Munich
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$140 - $470
Flights from Dresden to Stuttgart via Zurich
Ave. Duration
3 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $3,000
Flights from Prague to Strasbourg via Frankfurt
Ave. Duration
3 h 30 min
When
Monday
Estimated price
$130 - $550
Flights from Dresden to Frankfurt
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Munich
Ave. Duration
2 h 56 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Dusseldorf
Ave. Duration
2 h 55 min
When
Every day
Estimated price
$45 - $210
Flights from Prague to Zurich via Munich
Ave. Duration
3 h 8 min
When
Every day
Estimated price
$170 - $800
Flights from Prague to Zurich via Frankfurt
Ave. Duration
3 h 14 min
When
Every day
Estimated price
$170 - $800
Swiss
Website
swiss.com
Flights from Prague to Stuttgart via Zurich
Ave. Duration
3 h 40 min
When
Every day
Estimated price
$220 - $460
Flights from Dresden to Stuttgart via Zurich
Ave. Duration
3 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $3,000
Flights from Prague to Zurich
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$110 - $460
Eurowings
Website
eurowings.com
Flights from Prague to Stuttgart via Hamburg
Ave. Duration
3 h 40 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$85 - $650
Flights from Prague to Stuttgart via Dusseldorf
Ave. Duration
4 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$85 - $650
Flights from Dresden to Stuttgart
Ave. Duration
1 h 15 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$50 - $440
Austrian Airlines
Website
austrian.com
Flights from Prague to Stuttgart via Vienna
Ave. Duration
4 h
When
Every day
Estimated price
$190 - $450
Flights from Prague to Zurich via Vienna
Ave. Duration
3 h 40 min
When
Monday to Friday
Estimated price
$210 - $850
KLM
Website
klm.com
Flights from Prague to Stuttgart via Amsterdam
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$150 - $450
Flights from Prague to Strasbourg via Amsterdam
Ave. Duration
3 h 30 min
When
Monday to Saturday
Estimated price
$160 - $650
CSA
Website
csa.cz
Flights from Prague to Frankfurt
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$60 - $360
Flights from Prague to Strasbourg
Ave. Duration
1 h 35 min
When
Monday, Thursday and Friday
Estimated price
$75 - $700
easyJet
Website
easyjet.com
Flights from Prague to Stuttgart via Berlin Tegel
Ave. Duration
3 h 50 min
When
Tuesday and Thursday
Estimated price
$45 - $220
Flights from Prague to Stuttgart via Milan Malpensa
Ave. Duration
4 h 50 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$50 - $250
Flights from Prague to Stuttgart via Edinburgh
Ave. Duration
5 h 40 min
When
Monday and Friday
Estimated price
$90 - $470
Air France
Website
airfrance.com
Flights from Prague to Stuttgart via Paris CDG
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$150 - $490
Flights from Prague to Strasbourg via Lyon
Ave. Duration
4 h 10 min
When
Monday to Friday
Estimated price
$220 - $800
Scandinavian Airlines
Website
flysas.com
Flights from Prague to Stuttgart via Copenhagen
Ave. Duration
3 h 50 min
When
Sunday
Estimated price
$120 - $420
LOT
Website
lot.com
Flights from Prague to Stuttgart via Warsaw
Ave. Duration
6 h 10 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$95 - $350
Finnair
Website
finnair.com
Flights from Prague to Stuttgart via Helsinki
Ave. Duration
6 h 30 min
When
Monday, Wednesday, Friday and Saturday
Estimated price
$150 - $600
Turkish Airlines
Website
p.turkishairlines.com
Flights from Prague to Stuttgart via Istanbul
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$260 - $1,600
Brussels Airlines
Website
brusselsairlines.com
Flights from Prague to Stuttgart via Brussels
Ave. Duration
3 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $270
Hop!
Website
hop.com
Flights from Prague to Strasbourg via Lyon
Ave. Duration
4 h 10 min
When
Monday to Friday
Estimated price
$220 - $800
Vueling Airlines
Website
vueling.com
Flights from Prague to Zurich
Ave. Duration
1 h 20 min
When
Monday, Wednesday, Friday and Saturday
Estimated price
$100 - $550
Sichuan Airlines
Website
ch.com
Flights from Prague to Zurich
Ave. Duration
1 h 30 min
When
Wednesday and Saturday
Estimated price
$55 - $260
Train operators
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Nürnberg Hbf to Karlsruhe Hbf
Ave. Duration
3 h 14 min
Frequency
Every 3 hours
Estimated price
$60 - $85
Website
bahn.de
Train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
Ave. Duration
31 min
Frequency
Hourly
Estimated price
$22 - $35
Website
bahn.de
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
22 min
Frequency
Every 30 minutes
Estimated price
$20 - $29
Website
bahn.de
Train from Strasbourg to Karlsruhe Hbf
Ave. Duration
37 min
Frequency
5 times a day
Estimated price
$23 - $35
Website
bahn.de
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
25 min
Frequency
3 times a day
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$31 - $35
Train from Strasbourg to Karlsruhe Hbf
Ave. Duration
39 min
Frequency
Every 4 hours
Estimated price
$21 - $26
Website
en.oui.sncf
2nd Class
$21 - $26
1st Class
$37 - $39
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Zürich HB to Karlsruhe Hbf
Ave. Duration
2 h 49 min
Frequency
Every 2 hours
Estimated price
$70 - $120
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Praha, ÚAN Florenc to Karlsruhe, Hbf. - Süd, am Hintereingang
Ave. Duration
7 h 45 min
Frequency
3 times a week
Estimated price
$19 - $25
Schedules at
regiojet.sk
Bus from Praha, ÚAN Florenc to Drážďany, Letiště
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Schedules at
regiojet.sk
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Karlsruhe
Ave. Duration
8 h 45 min
Frequency
4 times a week
Estimated price
$30 - $80
Schedules at
elines.cz
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Prague Florenc to Karlsruhe
Ave. Duration
8 h 53 min
Frequency
4 times a week
Estimated price
$55 - $80
Website
eurolines.de
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Prague, Prague ,Hradčanská to Karlsruhe
Ave. Duration
9 h 50 min
Frequency
Twice daily
Estimated price
$30 - $55
Website
flixbus.co.uk
Bus from Stuttgart, Stuttgart Airport to Karlsruhe
Ave. Duration
55 min
Frequency
3 times a day
Estimated price
$4 - $8
Website
flixbus.co.uk
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Stuttgart to Karlsruhe
Ave. Duration
55 min
Frequency
Hourly
Estimated price
$3 - $5
Website
Ouibus

Want to know more about travelling around Germany

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Prague and Karlsruhe is 450 km. The road distance is 525 km.

The cheapest way to get from Prague to Karlsruhe is to bus which costs 430 Kč - 1 800 Kč and takes 7 h 45 min.

The quickest way to get from Prague to Karlsruhe is to drive which takes 4 h 39 min and costs 1 500 Kč - 2 200 Kč.

No, there is no direct train from Prague to Karlsruhe. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Karlsruhe Hbf via Nürnberg Hbf. The journey, including transfers, takes approximately 7 h 49 min.

Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Karlsruhe, Hbf. - Süd, am Hintereingang. Services depart twice daily, and operate every day. The journey takes approximately 7 h 45 min.

The bus from Praha, ÚAN Florenc to Karlsruhe, Hbf. - Süd, am Hintereingang takes 7 h 45 min including transfers and departs twice daily.