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There are 10 ways to get from Prague to Karlsruhe by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  7h 45m

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Karlsruhe Hbf Ic

$97 - $145

Cheapest option

Bus  •  8h 45m

  1. Take the bus from Praha ÚAN Florenc to Karlsruhe RegioJet / ...

$30 - $80

8 alternative options

Bus, train  •  9h 4m

  1. Take the bus from Praha hl. n. to Nuremberg
  2. Take the bus from Nuremberg Central Bus Station to Heilbronn Central Train Station
  3. Take the train from HN Hbf/W.-Brandt-Pl. to Karlsruhe Hbf Vorplatz S4

Drive  •  4h 39m

  1. Drive from Prague to Karlsruhe 328.1 miles

$65 - $100

Fly Prague to Stuttgart, bus  •  5h 10m

  1. Fly from Prague (PRG) to Stuttgart (STR) PRG - STR
  2. Take the bus from Stuttgart, Stuttgart Airport to Karlsruhe

$85 - $190

Bus to Dresden, fly to Stuttgart, bus  •  5h 50m

  1. Take the bus from Prague, ÚAN Florenc to Dresden, Letiště
  2. Fly from Dresden (DRS) to Stuttgart (STR) DRS - STR
  3. Take the bus from Stuttgart, Stuttgart Airport to Karlsruhe

$59 - $225

Fly Prague to Frankfurt, train  •  5h 7m

  1. Fly from Prague (PRG) to Frankfurt (FRA) PRG - FRA
  2. Take the train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
  3. Take the train from Mannheim Hbf to Karlsruhe Hbf

$95 - $285

Bus to Dresden, fly to Frankfurt, train  •  5h 57m

  1. Take the bus from Prague, ÚAN Florenc to Dresden, Letiště
  2. Fly from Dresden (DRS) to Frankfurt (FRA) DRS - FRA
  3. Take the train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
  4. Take the train from Mannheim Hbf to Karlsruhe Hbf

$109 - $320

Fly Prague to Strasbourg, train  •  6h

  1. Fly from Prague (PRG) to Strasbourg (SXB) PRG - SXB
  2. Take the train from Strasbourg to Karlsruhe Hbf

$111 - $371

Fly Prague to Zurich, train  •  7h 14m

  1. Fly from Prague (PRG) to Zurich (ZRH) PRG - ZRH
  2. Take the train from Zürich HB to Basel SBB
  3. Take the train from Basel SBB to Karlsruhe Hbf

$147 - $381

Questions & Answers

The cheapest way to get from Prague to Karlsruhe is to bus which costs 700 Kč - 1 700 Kč and takes 8h 45m.

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The quickest way to get from Prague to Karlsruhe is to drive which costs 1 500 Kč - 2 300 Kč and takes 4h 39m.

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Yes, there is a direct bus departing from Praha ÚAN Florenc and arriving at Karlsruhe. Services depart once daily, and operate every day. The journey takes approximately 8h 45m.

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No, there is no direct train from Prague to Karlsruhe. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Karlsruhe Hbf via Nürnberg Hbf. The journey, including transfers, takes approximately 7h 45m.

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The distance between Prague and Karlsruhe is 450 km. The road distance is 525 km.

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The best way to get from Prague to Karlsruhe without a car is to train which takes 7h 45m and costs 2 100 Kč - 3 300 Kč.

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It takes approximately 7h 45m to get from Prague to Karlsruhe, including transfers.

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Prague to Karlsruhe bus services, operated by Eurolines CZ, depart from Praha ÚAN Florenc station.

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Prague to Karlsruhe train services, operated by Czech Railways (ČD), depart from Praha hl.n. (Autobusová St. Wilsonova) station.

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The best way to get from Prague to Karlsruhe is to train which takes 7h 45m and costs 2 100 Kč - 3 300 Kč. Alternatively, you can bus, which costs 700 Kč - 1 700 Kč and takes 8h 45m.

Mode details

Map of how to get from Prague to Karlsruhe.
Launch map view
  • Distance: 281.4 miles
  • Duration: 7h 45m

What companies run services between Prague, Czech Republic and Karlsruhe, Germany?

You can take a train from Prague to Karlsruhe via Nürnberg ZOB and Nürnberg Hbf in around 7h 45m. Alternatively, Eurolines CZ operates a bus from Prague to Karlsruhe 4 times a week. Tickets cost $30 - $80 and the journey takes 8h 45m. Two other operators also service this route.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Stuttgart via Munich
Ave. Duration
3h 5m
When
Every day
Estimated price
$210 - $650
Flights from Prague to Stuttgart via Frankfurt
Ave. Duration
3h 7m
When
Every day
Estimated price
$210 - $650
Flights from Dresden to Stuttgart via Munich
Ave. Duration
2h 56m
When
Every day
Estimated price
$140 - $470
Flights from Dresden to Stuttgart via Frankfurt
Ave. Duration
2h 50m
When
Every day
Estimated price
$140 - $470
Flights from Prague to Frankfurt
Ave. Duration
1h 10m
When
Every day
Estimated price
$100 - $480
Flights from Prague to Frankfurt via Munich
Ave. Duration
3h 2m
When
Every day
Estimated price
$100 - $480
Flights from Dresden to Frankfurt
Ave. Duration
1h 5m
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Munich
Ave. Duration
2h 56m
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Dusseldorf
Ave. Duration
2h 55m
When
Monday to Saturday
Estimated price
$45 - $210
Flights from Prague to Strasbourg via Frankfurt
Ave. Duration
3h 55m
When
Monday
Estimated price
$130 - $550
Flights from Prague to Zurich via Munich
Ave. Duration
3h 6m
When
Every day
Estimated price
$170 - $800
Flights from Prague to Zurich via Frankfurt
Ave. Duration
3h 30m
When
Every day
Estimated price
$170 - $800
CSA
Website
csa.cz
Flights from Prague to Stuttgart
Ave. Duration
1h 20m
When
Monday and Tuesday
Estimated price
$55 - $230
Flights from Prague to Frankfurt
Ave. Duration
1h 25m
When
Every day
Estimated price
$60 - $360
Flights from Prague to Strasbourg
Ave. Duration
1h 35m
When
Monday, Thursday and Friday
Estimated price
$75 - $700
Swiss
Website
swiss.com
Flights from Prague to Stuttgart via Zurich
Ave. Duration
3h 32m
When
Every day
Estimated price
$220 - $460
Flights from Prague to Zurich
Ave. Duration
1h 20m
When
Every day
Estimated price
$110 - $460
Austrian Airlines
Website
austrian.com
Flights from Prague to Stuttgart via Vienna
Ave. Duration
3h 17m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $550
Flights from Prague to Zurich via Vienna
Ave. Duration
3h 5m
When
Friday and Sunday
Estimated price
$210 - $850
Eurowings
Website
eurowings.com
Flights from Prague to Stuttgart via Hamburg
Ave. Duration
3h 35m
When
Friday
Estimated price
$85 - $650
Flights from Dresden to Stuttgart
Ave. Duration
1h 5m
When
Every day
Estimated price
$50 - $440
Air France
Website
airfrance.com
Flights from Prague to Strasbourg via Lyon
Ave. Duration
3h 45m
When
Sunday
Estimated price
$230 - $900
Hop!
Website
hop.com
Flights from Prague to Strasbourg via Lyon
Ave. Duration
3h 45m
When
Sunday
Estimated price
$220 - $800
KLM
Website
klm.com
Flights from Prague to Strasbourg via Amsterdam Schiphol
Ave. Duration
4h
When
Monday to Saturday
Estimated price
$160 - $650
Sichuan Airlines
Website
ch.com
Flights from Prague to Zurich
Ave. Duration
1h 40m
When
Wednesday and Saturday
Estimated price
$55 - $260
Train operators
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3h 35m
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Nürnberg Hbf to Karlsruhe Hbf
Ave. Duration
3h 10m
Frequency
Every 3 hours
Estimated price
$55 - $85
Website
bahn.de
Train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
Ave. Duration
31m
Frequency
Hourly
Estimated price
$21 - $35
Website
bahn.de
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
22m
Frequency
Every 30 minutes
Estimated price
$19 - $28
Website
bahn.de
Train from Strasbourg to Karlsruhe Hbf
Ave. Duration
37m
Frequency
4 times a day
Estimated price
$23 - $35
Website
bahn.de
Train from Basel SBB to Karlsruhe Hbf
Ave. Duration
1h 45m
Frequency
Once daily
Estimated price
$35 - $50
Website
bahn.de
AVG
Phone
+49 721 61075885
Email
info@avg.karlsruhe.de
Website
avg.info
Train from HN Hbf/W.-Brandt-Pl. to Karlsruhe Hbf Vorplatz
Ave. Duration
1h 48m
Frequency
Every 30 minutes
Schedules at
avg.info
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Mannheim Hbf to Karlsruhe Hbf
Ave. Duration
25m
Frequency
3 times a day
Estimated price
$17 - $22
Website
en.oui.sncf
2nd Class
$17 - $22
1st Class
$30 - $35
Train from Strasbourg to Karlsruhe Hbf
Ave. Duration
39m
Frequency
Every 4 hours
Estimated price
$20 - $26
Website
en.oui.sncf
2nd Class
$20 - $26
1st Class
$37 - $39
Train from Zürich HB to Basel SBB
Ave. Duration
53m
Frequency
Every 3 hours
Estimated price
$22 - $28
Website
en.oui.sncf
2nd Class
$22 - $28
1st Class
$41 - $42
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Zürich HB to Basel SBB
Ave. Duration
1h 5m
Frequency
Every 15 minutes
Estimated price
$30 - $60
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Basel SBB to Karlsruhe Hbf
Ave. Duration
1h 45m
Frequency
Hourly
Estimated price
$40 - $70
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Karlsruhe
Ave. Duration
8h 45m
Frequency
4 times a week
Estimated price
$30 - $80
Schedules at
elines.cz
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Prague, ÚAN Florenc to Karlsruhe, Hbf. - Süd, am Hintereingang
Ave. Duration
7h 45m
Frequency
Once a week
Estimated price
$19 - $25
Website
regiojet.com
Bus from Prague, ÚAN Florenc to Dresden, Letiště
Ave. Duration
2h 20m
Frequency
4 times a day
Estimated price
$5 - $8
Website
regiojet.com
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Prague, Prague Hradčanská to Karlsruhe
Ave. Duration
9h 50m
Frequency
Once daily
Estimated price
$30 - $55
Website
flixbus.co.uk
Bus from Stuttgart, Stuttgart Airport to Karlsruhe
Ave. Duration
1h
Frequency
Hourly
Estimated price
$4 - $8
Website
flixbus.co.uk
Arriva Stredni Cechy
Website
arriva-strednicechy.cz
Bus from Praha hl. n. to Nuremberg
Ave. Duration
3h 35m
Frequency
Every 4 hours
Estimated price
$15 - $18
Schedules at
arriva.cz
Karat-S
Phone
+359 2 8120810
Email
operations@eurolines.bg
Website
karat-s.com
Bus from Nuremberg Central Bus Station to Heilbronn Central Train Station
Ave. Duration
2h 25m
Frequency
Once a week
Estimated price
$35 - $55
Website
Karat-S
Marino Autolinee
Phone
+39 080 3112335
Email
info@marinobus.it
Website
marinobus.it
Bus from Stuttgart to Karlsruhe
Ave. Duration
1h 10m
Frequency
Once daily
Estimated price
$7
Website
Marino Autolinee
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Stuttgart to Karlsruhe
Ave. Duration
1h 10m
Frequency
Once daily
Estimated price
$3 - $5
Website
Ouibus

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More Questions & Answers

The quickest flight from Prague Airport to Stuttgart Airport is the direct flight which takes 1h 20m.

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Prague to Karlsruhe bus services, operated by Eurolines CZ, arrive at Karlsruhe station.

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Prague to Karlsruhe train services, operated by Deutsche Bahn, arrive at Karlsruhe Hbf station.

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Yes, the driving distance between Prague to Karlsruhe is 525 km. It takes approximately 4h 39m to drive from Prague to Karlsruhe.

Get driving directions

CSA, Austrian Airlines, Eurowings and two other airlines offer flights from Prague Airport to Stuttgart Airport.

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Book your Prague to Karlsruhe bus tickets online with Distribusion and FlixBus.

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There are 234+ hotels available in Karlsruhe. Prices start at $63 USD per night.

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