There are 7 ways to get from Prague to Hesse by subway, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Václav Havel Airport Prague, fly
best- Take the subway from Staroměstská to Nádraží Veleslavínsubway
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
2h 44m€70–190Bus
cheapest- Take the bus from Praha, ÚAN Florenc to Frankfurt Central Train Stationbus RegioJet 540
6h 25m€18–40Train via Dresden
- Take the train from Praha-Holesovice to Dresden Hbftrain Rj
- Take the train from Dresden Hauptbahnhof to Frankfurttrain 50
7h 39m€111–273Drive 508.4 km
- Drive from Prague to Frankfurt am Maincar 508.4 km
4h 20m€79–113Train to Dresden Airport, fly
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
5h 18m€157–414Bus via Frankfurt
- Take the bus from Praha, ÚAN Florenc to Frankfurt central train stationbus N84 / ...
7h 12m€37–62Train
- Take the train from Praha Hlavni Nadrazi to Frankfurt(Main)Suedtrain Ec
9h 12m€145–245
Prague to Hesse by bus
Questions & Answers
The cheapest way to get from Prague to Hesse is to bus which costs €18 - €40 and takes 6h 25m.
The fastest way to get from Prague to Hesse is to subway and fly which takes 2h 44m and costs €70 - €190.
Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Frankfurt Central Train Station station. Services depart once daily, and operate every day. The journey takes approximately 6h 25m.
No, there is no direct train from Prague to Hesse. However, there are services departing from Praha-Holesovice and arriving at Frankfurt via Dresden Hauptbahnhof and Frankfurt. The journey, including transfers, takes approximately 7h 39m.
The distance between Prague and Hesse is 434 km. The road distance is 508.4 km.
The best way to get from Prague to Hesse without a car is to bus which takes 6h 25m and costs €18 - €40.
It takes approximately 2h 44m to get from Prague to Hesse, including transfers.
Prague to Hesse bus services, operated by RegioJet, depart from Praha, ÚAN Florenc station.
Prague to Hesse train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
The best way to get from Prague to Hesse is to bus which takes 6h 25m and costs €18 - €40. Alternatively, you can train via Dresden, which costs €110 - €280 and takes 7h 39m.
What companies run services between Prague, Czechia and Hesse, Germany?
RegioJet operates a bus from Praha, ÚAN Florenc to Frankfurt Central Train Station once daily. Tickets cost €30–50 and the journey takes 6h 25m. SARVALTEH AUTO also services this route once a week. Alternatively, you can take a train from Praha-Holesovice to Frankfurt via Dresden Hauptbahnhof and Frankfurt in around 7h 39m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–420
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–280
Flights from Dresden Airport to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €120–280
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- €65–160
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Tuesday to Sunday
- Estimated price
- €85–330
- Phone
- +420 234 704 560
- info@pid.cz
- Website
- pid.cz
Subway from Staroměstská to Nádraží Veleslavín
- Ave. Duration
- 9 min
- Frequency
- Every 10 minutes
- Estimated price
- €1–2
- Website
- https://pid.cz/en/
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 7m
- Frequency
- 4 times a day
- Estimated price
- €19–35
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 18m
- Frequency
- 6 times a week
- Estimated price
- €35–70
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Frankfurt(Main)Sued
- Ave. Duration
- 9h 4m
- Frequency
- 6 times a week
- Estimated price
- €140–250
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- €30–45
- Phone
- +47 70 13 14 15
- kundehenv@dsb.dk
- Website
- dsb.dk
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- https://www.dsb.dk/en/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Dresden Hauptbahnhof to Frankfurt
- Ave. Duration
- 4h 26m
- Frequency
- Every 3 hours
- Estimated price
- €90–200
- Website
- https://int.bahn.de/en
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Praha, ÚAN Florenc to Frankfurt Central Train Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- https://regiojet.com/
- helpline.svs@gmail.com
- Website
- svs.md
Bus from Praha, ÚAN Florenc to Frankfurt Central Train Station
- Ave. Duration
- 8h 44m
- Frequency
- Once a week
- Estimated price
- €18–40
- Website
- https://svs.md/en/bus/route/number-19167
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, ÚAN Florenc to Frankfurt central train station
- Ave. Duration
- 6h 55m
- Frequency
- Every 4 hours
- Estimated price
- €30–60
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Prague to Hesse bus services, operated by RegioJet, arrive at Frankfurt Central Train Station.
Prague to Hesse train services, operated by České dráhy (ČD), arrive at Dresden Hbf station.
Yes, the driving distance between Prague to Hesse is 508 km. It takes approximately 4h 20m to drive from Prague to Hesse.
Book your Prague to Hesse bus tickets online with Omio and Distribusion.
There are 1503+ hotels available in Hesse.





























