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How to get fromPrague to Hesseby bus, train, car, subway or plane

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There are 7 ways to get from Prague to Hesse by bus, train, car, subway, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Praha, ÚAN Florenc to Frankfurt Central Train StationbusRegioJet 540
    6h 25m
    €25–40
  2. Train via Dresden

    1. Take the train from Praha Hlavni Nadrazi to Dresden HbftrainEc
    2. Take the train from Dresden Hauptbahnhof to Frankfurttrain50
    7h 54m
    €53–137
  3. Drive 508.4 km

    1. Drive from Prague to Frankfurt am Maincar508.4 km
    4h 30m
    €77–111
  4. Subway to Václav Havel Airport Prague, fly

    1. Take the subway from Staroměstská to Nádraží Veleslavínsubway
    2. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)planePRG - FRA
    3h 56m
  5. Bus via Frankfurt

    1. Take the bus from Praha, ÚAN Florenc to Frankfurt central train stationbusN84 / ...
    7h 13m
    €29–70
  6. Train

    1. Take the train from Praha Hlavni Nadrazi to Frankfurt(Main)SuedtrainEc
    9h 12m
    €119–154
  7. Train to Dresden Airport, fly

    1. Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)planeDRS - FRA
    5h 34m
    €142–299

Prague to Hesse by bus

Calendar8Weekly Buses
Duration6h 25mAverage Duration
Ticket€25Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Hesse, Germany?

RegioJet operates a bus from Praha, ÚAN Florenc to Frankfurt Central Train Station once daily. Tickets cost €25–40 and the journey takes 6h 25m. SARVALTEH AUTO also services this route once a week. Alternatively, you can take a train from Praha Hlavni Nadrazi to Frankfurt via Dresden Hauptbahnhof and Frankfurt in around 7h 54m.

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