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How to get fromPrague to Grenobleby plane, train, bus, train (TGV) or car

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There are 6 ways to get from Prague to Grenoble by plane, train, bus, train (TGV), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lyon–Saint Exupéry Airport, train

    best
    1. Fly from Václav Havel Airport Prague (PRG) to Lyon–Saint Exupéry Airport (LYS)planePRG - LYS
    2. Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
    6h 16m
    €75–227
  2. Fly to Geneva International Airport, train

    cheapest
    1. Fly from Václav Havel Airport Prague (PRG) to Geneva International Airport (GVA)planePRG - GVA
    2. Take the train from Geneve to Grenobletrain
    7h 36m
    €73–200
  3. Bus

    1. Take the bus from Prague to GrenoblebusFlixBus N872
    15h 55m
    €80–120
  4. Train

    1. Take the train from Praha Hlavni Nadrazi to Dresden HbftrainEc
    2. Take the train from Dresden Hauptbahnhof to Erfurt Hbftrain50 / ...
    3. Take the train from Erfurt Hbf to Strasbourg Bahnhoftrain82
    4. Take the train from Strasbourg Bahnhof to Lyon Part Dieutrain84
    5. Take the train from Lyon Part Dieu to GrenobletrainTer
    16h 55m
    €185–564
  5. Drive 1,054.1 km

    1. Drive from Prague to Grenoblecar1,054.1 km
    10h 13m
    €161–232
  6. Bus, train

    1. Take the bus from Prague - Florenc Main Bus Terminal to Valence - Central Bus StationbusBlaBlaCar Bus
    2. Take the train from Valence Ville to GrenobletrainTer
    20h 14m
    €94–120

Prague to Grenoble by bus

Calendar8Weekly Buses
Duration15h 55mAverage Duration
Ticket€80Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Grenoble, France?

FlixBus operates a bus from Prague to Grenoble once daily. Tickets cost €80–120 and the journey takes 15h 55m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Grenoble via Dresden Hauptbahnhof, Erfurt Hbf, Strasbourg Bahnhof, and Lyon Part Dieu in around 16h 55m.

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