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How to get fromPoughkeepsie to West Senecaby train (Amtrak), car, train or plane

Find Transport to West Seneca

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There are 5 ways to get from Poughkeepsie to West Seneca by train (Amtrak), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Poughkeepsie Amtrak Station to Buffalo Depew StationtrainMaple Leaf / ...
    6h 46m
    $78–159

  2. Drive 325.2 mi

    cheapest
    1. Drive from Poughkeepsie to West Senecacar325.2 mi
    6h 25m
    $60–86

  3. Train to Laguardia Airport, fly

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)planeLGA - BUF
    6h 56m
    $165–1,065

  4. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)planeJFK - BUF
    7h 16m
    $167–1,027

  5. Train to Newark Liberty International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)planeEWR - BUF
    7h 47m
    $159–1,193

Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF) flights

Calendar55Weekly Planes
Duration2h 18mAverage Duration
Ticket$143Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and West Seneca, NY, USA?

Amtrak operates a train from Poughkeepsie Amtrak Station to Buffalo Depew Station 4 times a day. Tickets cost $70–130 and the journey takes 6h 34m. VIA Rail also services this route once daily.

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