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How to get fromPoughkeepsie to Walthamby train (Amtrak), bus, car, train, or plane

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There are 8 ways to get from Poughkeepsie to Waltham by train (Amtrak), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the train from 125th Street - Harlem to Stamfordtrain train
    3. Take the train from Stamford Amtrak Station to Bostontrain train
    6h 22m
    $88–178

  2. Drive 170.6 mi

    cheapest
    1. Drive from Poughkeepsie to Walthamcar car 170.6 mi
    3h 38m
    $32–45

  3. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus bus ShortLine Hudson
    2. Take the bus from Manhattan, NY to Newton, MAbus bus Manhattan-Cambridge
    8h 51m
    $57–114

  4. Train to Laguardia Airport, fly

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    5h 31m
    $199–647

  5. Train via Pittsfield (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train Berkshire Flyer
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train Lake Shore Limited
    9h 18m
    $83–180

  6. Train, bus

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train Berkshire Flyer
    2. Take the bus from Pittsfield to Bostonbus bus Greyhound US0270s
    9h 24m
    $59–120

  7. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Boston Logan Airport (BOS)plane plane JFK - BOS
    5h 46m
    $242–859

  8. Train to Newark Liberty International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)plane plane EWR - BOS
    5h 29m
    $203–638

Poughkeepsie to Waltham by train and bus

Calendar114Weekly Services
Duration6h 22mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Poughkeepsie to Waltham.ExpandLaunch map view
  • Distance: 297.5 mi
  • Duration: 6h 22m

What companies run services between Poughkeepsie, NY, USA and Waltham, MA, USA?

You can take a train from Poughkeepsie to Washington St @ Bacon St via 125th Street - Harlem, Stamford, Stamford Amtrak Station, Boston, and Saint James Ave @ Dartmouth St in around 6h 22m. Alternatively, you can take a train from Poughkeepsie to Newton, MA via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, and Manhattan, NY in around 8h 51m.

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