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How to get fromPoughkeepsie to Walthamby train (Amtrak), train, bus, car, plane or bus (Greyhound, Flixbus)

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There are 8 ways to get from Poughkeepsie to Waltham by train (Amtrak), train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via New York (Amtrak)

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    6h 20m
    $59–811
  2. Drive 169.7 mi

    cheapest
    1. Drive from Poughkeepsie to Walthamcar car 169.7 mi
    3h 41m
    $31–45
  3. Train, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train Hudson
    2. Take the bus from Manhattan, NY to Newton, MAbus bus Manhattan-Cambridge
    6h 57m
    $47–75
  4. Train to Laguardia Airport, fly

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    5h 31m
    $114–437
  5. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train Berkshire Flyer
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train Lake Shore Limited
    8h 31m
    $39–151
  6. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from White Plains Bus Station to Hartford Union Stationbus bus
    3. Take the bus from Hartford Union Station to Bostonbus bus
    9h 35m
    $45–83
  7. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Boston Logan Airport (BOS)plane plane JFK - BOS
    5h 46m
    $361–809
  8. Train to Newark Liberty International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)plane plane EWR - BOS
    6h 17m
    $134–630

Poughkeepsie to Waltham by train and bus (Amtrak)

Calendar63Weekly Services
Duration6h 20mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Waltham, MA, USA?

You can take a train from Poughkeepsie Amtrak Station to Washington St @ Bacon St via Ny Moynihan Train Hall At Penn Station, Boston, and Saint James Ave @ Dartmouth St in around 6h 20m. Alternatively, you can take a bus from Metro North Station to Moody St @ Carter St via TransCenter, White Plains Bus Station, Hartford Union Station, Boston, and Federal St @ Franklin St in around 9h 35m.

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