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There are 9 ways to get from Poughkeepsie to South Carolina by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to New York La Guardia, fly to Greenville/Spartanburg  •  5 h 40 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Fly from New York La Guardia (LGA) to Greenville/Spartanburg (GSP) LGA - GSP

$192 - $811

Cheapest option

Train, bus  •  16 h 4 min

  1. Take the train from Poughkeepsie to Grand Central Hudson
  2. Take the bus from New York, NY to Florence, SC Nyc / ...

$86 - $107

7 alternative options

Train to Newark, fly to Charleston  •  6 h 39 min

  1. Take the train from Poughkeepsie to Grand Central
  2. Fly from Newark (EWR) to Charleston (CHS) EWR - CHS

$176 - $855

Train to New York JFK, fly to Charleston  •  6 h 31 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Fly from New York JFK (JFK) to Charleston (CHS) JFK - CHS

$158 - $718

Train to New York La Guardia, fly to Charleston  •  6 h 35 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station
  2. Fly from New York La Guardia (LGA) to Charleston (CHS) LGA - CHS

$184 - $869

Train to White Plains, fly to Charlotte, bus  •  9 h 1 min

  1. Take the train from Poughkeepsie to Tarrytown
  2. Fly from White Plains (HPN) to Charlotte (CLT) HPN - CLT
  3. Take the bus from Transit Center- Bay X to White Street Park and Ride

$184 - $746

Train  •  14 h 23 min

  1. Take the train from Poughkeepsie Amtrak Station to New York Penn Station Empire Service / ...
  2. Take the train from New York Penn Station to Florence Amtrak Station Palmetto / ...

$117 - $314

Bus  •  20 h 22 min

  1. Take the bus from New Paltz to New York, Port Authority
  2. Take the bus from New York, Ny to Fayetteville, Nc
  3. Take the bus from Fayetteville, Nc to Florence, Sc

$90 - $242

Drive  •  12 h 5 min

  1. Drive from Poughkeepsie to Florence 709.3 miles

$65 - $100

Questions & Answers

The cheapest way to get from Poughkeepsie to South Carolina is to drive which costs $65 - $100 and takes 12 h 5 min.

More details

The quickest way to get from Poughkeepsie to South Carolina is to train and fly which costs $190 - $850 and takes 5 h 40 min.

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No, there is no direct bus from Poughkeepsie to South Carolina. However, there are services departing from Poughkeepsie Main & Market and arriving at Florence, Sc via New Paltz, New York, Ny and Fayetteville, Nc. The journey, including transfers, takes approximately 20 h 22 min.

More details

No, there is no direct train from Poughkeepsie station to South Carolina station. However, there are services departing from Poughkeepsie Amtrak Station and arriving at Florence Amtrak Station via New York Penn Station. The journey, including transfers, takes approximately 14 h 23 min.

More details

The distance between Poughkeepsie and South Carolina is 662 miles. The road distance is 709.3 miles.

Get driving directions

The best way to get from Poughkeepsie to South Carolina without a car is to train which takes 14 h 23 min and costs $110 - $320.

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It takes approximately 5 h 40 min to get from Poughkeepsie to South Carolina, including transfers.

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Poughkeepsie to South Carolina bus services, operated by Trailways New York, depart from New Paltz station.

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Poughkeepsie to South Carolina train services, operated by Amtrak, arrive at Poughkeepsie Amtrak Station.

More details

The best way to get from Poughkeepsie to South Carolina is to train which takes 14 h 23 min and costs $110 - $320. Alternatively, you can bus, which costs $85 - $250 and takes 20 h 22 min.

Mode details

Map of how to get from Poughkeepsie to South Carolina.
Launch map view
  • Distance: 661.7 miles
  • Duration: 5 h 40 min

What companies run services between Poughkeepsie, NY, USA and South Carolina, USA?

You can take a train from Poughkeepsie to Florence via New York Penn Station in around 14 h 23 min. Alternatively, you can take a bus from Poughkeepsie to Florence via New Paltz, New York, Port Authority, New York, Ny, and Fayetteville, Nc in around 20 h 22 min.

Airlines
American Airlines
Website
aa.com
Flights from New York La Guardia to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$290 - $900
Flights from New York La Guardia to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$290 - $900
Flights from New York La Guardia to Greenville/Spartanburg via Reagan Washington
Ave. Duration
4 h 15 min
When
Monday to Friday
Estimated price
$290 - $900
Flights from Newark to Charleston via Charlotte
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$270 - $1,500
Flights from New York JFK to Charleston via Reagan Washington
Ave. Duration
4 h 12 min
When
Monday, Tuesday, Thursday and Sunday
Estimated price
$210 - $1,300
Flights from New York JFK to Charleston via Charlotte
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$210 - $1,300
Flights from New York La Guardia to Charleston
Ave. Duration
2 h 23 min
When
Saturday and Sunday
Estimated price
$230 - $1,100
Flights from New York La Guardia to Charleston via Charlotte
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$230 - $1,100
Flights from New York La Guardia to Charleston via Reagan Washington
Ave. Duration
4 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from White Plains to Charlotte
Ave. Duration
2 h 2 min
When
Every day
Estimated price
$330 - $1,000
Flights from White Plains to Charlotte via Reagan Washington
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$330 - $1,000
United Airlines
Website
united.com
Flights from New York La Guardia to Greenville/Spartanburg via Washington Dulles
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$330 - $1,400
Flights from Newark to Charleston
Ave. Duration
2 h 12 min
When
Every day
Estimated price
$230 - $1,800
Flights from Newark to Charleston via Washington Dulles
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$230 - $1,800
Flights from New York La Guardia to Charleston via Washington Dulles
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$310 - $2,000
Delta
Website
delta.com
Flights from New York La Guardia to Greenville/Spartanburg
Ave. Duration
2 h 18 min
When
Every day
Estimated price
$260 - $800
Flights from New York JFK to Charleston
Ave. Duration
2 h 31 min
When
Every day
Estimated price
$180 - $950
Flights from New York La Guardia to Charleston
Ave. Duration
2 h 30 min
When
Every day
Estimated price
$250 - $1,500
Flights from White Plains to Charlotte via Atlanta
Ave. Duration
4 h 58 min
When
Monday to Friday
Estimated price
$310 - $1,400
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Charleston
Ave. Duration
2 h 18 min
When
Every day
Estimated price
$180 - $1,300
Southwest Airlines
Website
southwest.com
Flights from New York La Guardia to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 25 min
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $800
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Poughkeepsie Amtrak Station to New York Penn Station
Ave. Duration
1 h 33 min
Frequency
Every 3 hours
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from New York Penn Station to Florence Amtrak Station
Ave. Duration
11 h 50 min
Frequency
Twice daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Metro-North Railroad (MNR)
Phone
+1 877-690-5116
Website
mta.info
Train from Poughkeepsie to Grand Central
Ave. Duration
1 h 52 min
Frequency
Hourly
Estimated price
$17 - $35
Schedules at
mta.info
Off-peak at station
$17 - $19
Off-peak onboard
$23 - $25
Onboard
$25 - $35
At station
$24 - $27
Train from Poughkeepsie to Tarrytown
Ave. Duration
1 h 7 min
Frequency
Hourly
Estimated price
$13 - $27
Schedules at
mta.info
Off-peak at station
$13 - $15
Off-peak onboard
$19 - $21
Onboard
$19 - $27
At station
$16 - $20
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1 h 12 min
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Florence, SC
Ave. Duration
12 h
Frequency
5 times a day
Estimated price
$55
Schedules at
wandacoach.com
Starline Bus
Website
starlinebus.com
Bus from New York, NY to Florence, SC
Ave. Duration
11 h 15 min
Frequency
Twice daily
Estimated price
$55
Schedules at
starlinebus.com
Book at
gotobus.com
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from New Paltz to New York, Port Authority
Ave. Duration
1 h 40 min
Frequency
Every 4 hours
Estimated price
$19 - $65
Book at
trailwaysny.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New York, Ny to Fayetteville, Nc
Ave. Duration
13 h 45 min
Frequency
Every 4 hours
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
5 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35

Want to know more about travelling around United States

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More Questions & Answers

The quickest flight from New York La Guardia Airport to Greenville/Spartanburg Airport is the direct flight which takes 2 h 12 min.

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Poughkeepsie to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

More details

Poughkeepsie to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak Station.

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Yes, the driving distance between Poughkeepsie to South Carolina is 709 miles. It takes approximately 12 h 5 min to drive from Poughkeepsie to South Carolina.

Get driving directions

Southwest Airlines, Delta, United Airlines and American Airlines offer flights from New York La Guardia Airport to Greenville/Spartanburg Airport.

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Book your Poughkeepsie to South Carolina train tickets online with Rome2rio.

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There are 19+ hotels available in South Carolina. Prices start at $49 USD per night.

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