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How to get fromPoughkeepsie to Louisvilleby train, plane, bus, bus (Greyhound) or car

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There are 10 ways to get from Poughkeepsie to Louisville by train, plane, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Louisville International Airport

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    7h 1m
    $160–496

  2. Train to Laguardia Airport, fly to Blue Grass Airport, drive

    cheapest
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 59m
    $97–442

  3. Train, bus via Toledo

    1. Take the train from Poughkeepsie Amtrak Station to Toledotrain train
    2. Take the bus from Toledo to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    21h 33m
    $106–314

  4. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Columbusbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    23h 9m
    $127–334

  5. Drive 774.5 mi

    1. Drive from Poughkeepsie to Louisvillecar car 774.5 mi
    13h 49m
    $142–205

  6. Train to Newark Liberty International Airport, fly to Louisville International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    7h 47m
    $190–669

  7. Train to Laguardia Airport, fly to Covington, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Covington (CVG)plane plane LGA - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    9h 42m
    $140–780

  8. Train to John F. Kennedy International Airport, fly to Covington, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Covington (CVG)plane plane JFK - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    9h 59m
    $142–742

  9. Train, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the bus from New York City Chinatown to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 30m
    $131–328

  10. Train, bus #2 (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    28h 30m
    $170–431

Poughkeepsie to Louisville by train and bus

Calendar7Weekly Services
Duration21h 33mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Louisville, KY, USA?

You can take a train from Poughkeepsie to Louisville, KY Bus Station via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, and Columbus - Downtown - Mound St in around 23h 9m.

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