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How to get fromPoughkeepsie to Lexingtonby train, plane, car, bus, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Poughkeepsie to Lexington by train, plane, car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Louisville International Airport, drive

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 7m
    $155–757

  2. Drive 736.9 mi

    cheapest
    1. Drive from Poughkeepsie to Lexingtoncar car 736.9 mi
    13h 20m
    $135–195

  3. Train, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the bus from New York, NY to Sharonville/Cincinnati, OHbus bus Nyc
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    18h 58m
    $178–215

  4. Train, bus via Toledo

    1. Take the train from Poughkeepsie Amtrak Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo Bus Stop to Lexington Bus Stopbus bus Greyhound US0110
    21h 20m
    $280–547

  5. Train to Laguardia Airport, fly to Blue Grass Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    7h 47m
    $203–988

  6. Train to Newark Liberty International Airport, fly to Louisville International Airport, drive

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 4m
    $158–647

  7. Train, train to Philadelphia International Airport, fly to Blue Grass Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    9h 1m
    $239–1,753

  8. Train to Newark Liberty International Airport, fly to Covington, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Covington (CVG)plane plane EWR - CVG
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    10h 6m
    $347–1,267

  9. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus bus
    2. Take the bus from New York Midtown to Dayton Trotwood Bus Stationbus bus
    3. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus
    24h 21m
    $180–313

  10. Train, bus via Indianapolis

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    30h 47m

Laguardia Airport (LGA) to Louisville International Airport (SDF) flights

Calendar59Weekly Planes
Duration3h 45mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Poughkeepsie to Lexington.ExpandLaunch map view
  • Distance: 812.7 mi
  • Duration: 7h 7m

What companies run services between Poughkeepsie, NY, USA and Lexington, KY, USA?

You can take a train from Poughkeepsie to Lexington via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, New York Midtown, Dayton Trotwood Bus Station, and Lexington Bus Stop in around 24h 21m.

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