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How to get fromPoughkeepsie to Indianapolisby train, plane, bus, car, bus (Flixbus) or train (Amtrak)

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There are 9 ways to get from Poughkeepsie to Indianapolis by train, plane, bus, car, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Indianapolis (IND)plane plane LGA - IND
    6h 51m
    $141–415

  2. Train, bus via Toledo

    cheapest
    1. Take the train from Poughkeepsie Amtrak Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit
    18h 8m
    $84–269

  3. Train, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train Hudson
    2. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus Greyhound US0421
    20h 12m
    $115–314

  4. Drive 753.2 mi

    1. Drive from Poughkeepsie to Indianapoliscar car 753.2 mi
    12h 49m
    $138–199

  5. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Indianapolis (IND)plane plane JFK - IND
    7h 2m
    $108–457

  6. Train to Newark Liberty International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Indianapolis (IND)plane plane EWR - IND
    7h 32m
    $85–493

  7. Train, train to Philadelphia International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Indianapolis (IND)plane plane PHL - IND
    8h 21m
    $131–1,013

  8. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from New York Midtown to Indianapolisbus bus FlixBus N2640
    21h 31m
    $111–281

  9. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train Cardinal
    25h 5m
    $157–1,171

Poughkeepsie to Indianapolis by train and bus

Calendar7Weekly Services
Duration18h 8mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Indianapolis, IN, USA?

You can take a bus from Metro North Station to Indianapolis via TransCenter, White Plains Bus Station, and New York Midtown in around 21h 31m. Alternatively, you can take a train from Poughkeepsie Amtrak Station to Indianapolis via Ny Moynihan Train Hall At Penn Station in around 25h 5m.

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