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How to get fromPoughkeepsie to Indianaby train, plane, bus, car, bus (Flixbus) or train (Amtrak)

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There are 11 ways to get from Poughkeepsie to Indiana by train, plane, bus, car, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Indianapolis

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Laguardia Airport (LGA) to Indianapolis (IND)planeLGA - IND
    6h 45m
    $106–385

  2. Train, bus via Toledo

    cheapest
    1. Take the train from Poughkeepsie Amtrak Station to ToledotrainLake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbusDetroit
    18h 8m
    $84–269

  3. Train, bus

    1. Take the train from Poughkeepsie to Grand Central TerminaltrainHudson
    2. Take the bus from Port Authority Bus Terminal to Indianapolis Union StationbusGreyhound US0421
    20h 12m
    $115–264

  4. Drive 753 mi

    1. Drive from Poughkeepsie to Indianapoliscar753 mi
    12h 43m
    $138–199

  5. Train to John F. Kennedy International Airport, fly to Indianapolis

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain
    2. Fly from John F. Kennedy International Airport (JFK) to Indianapolis (IND)planeJFK - IND
    7h 1m
    $98–407

  6. Train to Laguardia Airport, fly to Chicago Midway International Airport, train

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Laguardia Airport (LGA) to Chicago Midway International Airport (MDW)planeLGA - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    7h 33m
    $103–457

  7. Train to Newark Liberty International Airport, fly to Indianapolis

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Fly from Newark Liberty International Airport (EWR) to Indianapolis (IND)planeEWR - IND
    7h 24m
    $90–474

  8. Train to Albany County Airport, fly to Chicago Midway International Airport, train

    1. Take the train from Poughkeepsie Amtrak Station to Albany-Rensselaer Amtrak Stationtrain
    2. Fly from Albany County Airport (ALB) to Chicago Midway International Airport (MDW)planeALB - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    7h 52m
    $137–695

  9. Train to Westchester County Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Westchester County Airport (HPN) to Chicago O'Hare International Airport (ORD)planeHPN - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    9h 50m
    $507–957

  10. Bus

    1. Take the bus from Rosendale, Ny to Port Authority Bus Terminalbus9121 / ...
    2. Take the bus from New York Midtown to IndianapolisbusFlixBus N2640
    21h 28m
    $122–285

  11. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn StationtrainEmpire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to IndianapolistrainCardinal
    25h 5m
    $182–672

Poughkeepsie to Indiana by train and bus

Calendar7Weekly Services
Duration18h 8mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Indiana, USA?

You can take a bus from Poughkeepsie Main & Market to Indianapolis via Rt 32 & Henry Dubois Dr, Rosendale Park & Ride, Rosendale, Ny, Port Authority Bus Terminal, and New York Midtown in around 21h 28m. Alternatively, you can take a train from Poughkeepsie Amtrak Station to Indianapolis via Ny Moynihan Train Hall At Penn Station in around 25h 5m.

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