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How to get fromPoughkeepsie to Hyannisby train, bus, car, plane or bus (Flixbus)

Find Transport to Hyannis

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There are 10 ways to get from Poughkeepsie to Hyannis by train, bus, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via New York

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus
    8h 33m
    $72–861
  2. Drive 216.5 mi

    cheapest
    1. Drive from Poughkeepsie to Hyanniscar216.5 mi
    5h 12m
    $40–58
  3. Train, bus

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain
    2. Take the bus from Pittsfield to Bostonbus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus
    10h 2m
    $67–153
  4. Train to Laguardia Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Laguardia Airport (LGA) to Barnstable Municipal Airport (HYA)planeLGA - HYA
    5h 19m
    $332–636
  5. Train, bus #2

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain
    2. Take the train from Pittsfield Amtrak Station to Bostontrain
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus
    9h 59m
    $61–193
  6. Bus

    1. Take the bus from Rosendale, Ny to Albany Sunybus412
    2. Take the bus from Albany to Bostonbus
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus
    10h 41m
    $58–165
  7. Train to John F. Kennedy International Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain
    2. Fly from John F. Kennedy International Airport (JFK) to Barnstable Municipal Airport (HYA)planeJFK - HYA
    5h 43m
    $334–508
  8. Train to Laguardia Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)planeLGA - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus
    7h 22m
    $147–453
  9. Train to Westchester County Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain
    2. Fly from Westchester County Airport (HPN) to Barnstable Municipal Airport (HYA)planeHPN - HYA
    8h 49m
    $331–536
  10. Train to Newark Liberty International Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    2. Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)planeEWR - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus
    8h 3m
    $146–621

Poughkeepsie to Hyannis by train and bus

Calendar63Weekly Services
Duration8h 33mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

What companies run services between Poughkeepsie, NY, USA and Hyannis, MA, USA?

You can take a bus from Poughkeepsie Main & Market to Hyannis Transportation Center via Rt 32 & Henry Dubois Dr, Rosendale Park & Ride, Rosendale, Ny, Albany Suny, Albany, Boston, and Boston South Station in around 10h 41m.

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