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How to get fromPoughkeepsie to Hyannisby train, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Poughkeepsie to Hyannis by train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    3. Take the bus from Boston to Hyannisbus bus
    8h 43m
    $93–206

  2. Drive  217.4 mi

    cheapest
    1. Drive from Poughkeepsie to Hyanniscar car 217.4 mi
    5h 12m
    $40–58

  3. Train, bus via New Haven

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the train from 125th Street - Harlem to New Haventrain train
    3. Take the bus from New Haven to Providencebus bus
    4. Take the bus from Providence to Hyannisbus bus
    9h 50m
    $72–124

  4. Train to John F. Kennedy International Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Barnstable Municipal Airport (HYA)plane plane JFK - HYA
    6h 23m
    $383–1,147

  5. Train, bus #2

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    9h 58m
    $92–192

  6. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from Stamford Bus Stop to Hartford Union Stationbus bus
    3. Take the bus from Hartford Union Station to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    10h 59m
    $55–92

  7. Train to Laguardia Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 14m
    $104–476

  8. Train to Westchester County Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Barnstable Municipal Airport (HYA)plane plane HPN - HYA
    7h 37m
    $339–695

Poughkeepsie to Hyannis by train, foot, and bus

Calendar63Weekly Services
Duration8h 43mAverage Duration
Ticket$93Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to Hyannis.ExpandLaunch map view
  • Distance: 375.7 mi
  • Duration: 8h 43m

What companies run services between Poughkeepsie, NY, USA and Hyannis, MA, USA?

You can take a bus from Metro North Station to Hyannis Transportation Center via White Plains Transportation Center, Stamford Transportation Center @ Bay A, Stamford Bus Stop, Hartford Union Station, Boston, and Boston South Buses in around 10h 59m.

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