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How to get fromPoughkeepsie to Durhamby train, plane, train (Amtrak), bus (Flixbus), car, or bus

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There are 10 ways to get from Poughkeepsie to Durham by train, plane, train (Amtrak), bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Raleigh-Durham International Airport

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane plane LGA - RDU
    6h 26m
    $147–482

  2. Drive  553 mi

    cheapest
    1. Drive from Poughkeepsie to Durhamcar car 553 mi
    10h 5m
    $101–146

  3. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    15h 21m
    $340–542

  4. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus bus ShortLine Hudson
    2. Take the bus from New York Midtown to Durhambus bus FlixBus N2471 / ...
    15h 29m
    $107–176

  5. Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    6h 20m
    $178–997

  6. Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)plane plane JFK - RDU
    6h 54m
    $419–1,753

  7. Train to Laguardia Airport, fly to Piedmont Triad International Airport, train

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)plane plane LGA - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 15m
    $160–611

  8. Train, train to Long Island Mac Arthur Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from New York Penn Station to Central Isliptrain train
    3. Fly from Long Island Mac Arthur Airport (ISP) to Raleigh-Durham International Airport (RDU)plane plane ISP - RDU
    7h 59m
    $161–749

  9. Train to Westchester County Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)plane plane HPN - RDU
    8h 23m
    $175–951

  10. Train, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train Hudson
    2. Take the bus from Port Authority Bus Terminal to Durhambus bus Greyhound US0670
    16h 27m
    $117–187

Poughkeepsie to Durham by train (Amtrak)

Calendar7Weekly Trains
Duration15h 21mAverage Duration
Ticket$340Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to Durham.ExpandLaunch map view
  • Distance: 523.3 mi
  • Duration: 6h 26m

What companies run services between Poughkeepsie, NY, USA and Durham, NC, USA?

You can take a train from Poughkeepsie Amtrak Station to Durham Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 15h 21m. Alternatively, you can take a train from Poughkeepsie to Durham via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, and New York Midtown in around 15h 29m.

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