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How to get fromPoughkeepsie to Cape Codby train, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Poughkeepsie to Cape Cod by train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    3. Take the bus from Boston to Hyannisbus bus
    9h 46m
    $174–287

  2. Drive  220.9 mi

    cheapest
    1. Drive from Poughkeepsie to Cape Codcar car 220.9 mi
    5h 15m
    $41–59

  3. Train, bus via New Haven

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the train from 125th Street - Harlem to New Haventrain train
    3. Take the bus from New Haven to Providencebus bus
    4. Take the bus from Providence to Hyannisbus bus
    10h 53m
    $72–124

  4. Train to Laguardia Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Barnstable Municipal Airport (HYA)plane plane LGA - HYA
    6h 32m
    $92–537

  5. Train, bus #2

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    11h 1m
    $172–265

  6. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from White Plains Bus Station to Hartford Union Stationbus bus
    3. Take the bus from Hartford Union Station to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    11h 28m
    $58–93

  7. Train to John F. Kennedy International Airport, fly to Barnstable Municipal Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Barnstable Municipal Airport (HYA)plane plane JFK - HYA
    6h 55m
    $384–1,048

  8. Train to Laguardia Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    8h 13m
    $104–496

  9. Train to Newark Liberty International Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)plane plane EWR - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    8h 19m
    $570–1,731

Poughkeepsie to Cape Cod by train, foot, and bus

Calendar63Weekly Services
Duration9h 46mAverage Duration
Ticket$174Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to Cape Cod.ExpandLaunch map view
  • Distance: 381.8 mi
  • Duration: 9h 46m

What companies run services between Poughkeepsie, NY, USA and Cape Cod, MA, USA?

You can take a bus from Metro North Station to Town Hall Lawton Bus Shelter via TransCenter, White Plains Bus Station, Hartford Union Station, Boston, Boston South Buses, and Hyannis Transportation Center in around 11h 28m.

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