Rome2Rio

How to get fromPotomac to St. Louisby plane, bus (Greyhound), train (Amtrak), car, train, subway or bus

Find Transport to St. Louis

See all options

There are 7 ways to get from Potomac to St. Louis by plane, bus (Greyhound), train (Amtrak), car, train, subway, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Ronald Reagan Washington National Airport

    best
    1. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    5h
    $269–1,513

  2. Bus

    cheapest
    1. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus 515
    2. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus
    20h 37m
    $136–283

  3. Train (Amtrak)

    1. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    24h 20m
    $302–662

  4. Drive 791.4 mi

    1. Drive from Potomac to St. Louiscar car 791.4 mi
    13h 46m
    $145–209

  5. Train to Baltimore-Washington International Airport, fly

    1. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    5h 30m
    $269–1,020

  6. Subway to Washington Dulles International Airport, fly

    1. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Lambert–St. Louis International Airport (STL)plane plane IAD - STL
    5h 43m
    $139–767

  7. Train, bus

    1. Take the train from Rockville Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    22h 32m
    $182–392

Potomac to St. Louis by bus and subway

Calendar10Weekly Services
Duration20h 37mAverage Duration
Ticket$136Cheapest Price
See schedules

Questions & Answers

What companies run services between Potomac, Montgomery County, MD, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Falls Rd+Glenolden Rd to St Louis Bus Station via Rockville+Bay A, Rockville, Red Line Center Platform, Shady Grove, Red Line Center Platform, SHADY GROVE & station, Frederick Bus Station, and Pittsburgh Intermodal Station in around 20h 37m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Potomac

Trips to St. Louis

Popular routes