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How to get fromPortland to Knoxvilleby plane, train, bus, bus (Flixbus, Greyhound), or car

Find Transport to Knoxville

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There are 7 ways to get from Portland to Knoxville by plane, train, bus, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Portland International Airport (PDX) to Mcghee Tyson Airport (TYS)plane plane PDX - TYS
    8h 17m
    $418–1,473

  2. Fly to Nashville, drive

    cheapest
    1. Fly from Portland International Airport (PDX) to Nashville (BNA)plane plane PDX - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 50m
    $223–853

  3. Train, bus via Chicago

    1. Take the train from Portland to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 8h
    $1,107–2,152

  4. Bus

    1. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to New York Midtownbus bus
    5. Take the bus from New York to Knoxvillebus bus
    3d 13h
    $671–1,139

  5. Drive 2,495.3 mi

    1. Drive from Portland to Knoxvillecar car 2,495.3 mi
    40h 34m
    $456–658

  6. Fly to Asheville Regional Airport, drive

    1. Fly from Portland International Airport (PDX) to Asheville Regional Airport (AVL)plane plane PDX - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    10h 22m
    $225–838

  7. Train, bus

    1. Take the train from Portland to Vancouvertrain train
    2. Take the train from Vancouver to Toronto Union Stationtrain train
    3. Take the train from Toronto Union Station to New York Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus
    5d 9h
    $603–1,028

Portland International Airport (PDX) to Mcghee Tyson Airport (TYS) flights

Calendar87Weekly Planes
Duration7h 29mAverage Duration
Ticket$365Cheapest Price
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Questions & Answers

Map of how to get from Portland to Knoxville.ExpandLaunch map view
  • Distance: 2,132.4 mi
  • Duration: 8h 17m

What companies run services between Portland, OR, USA and Knoxville, TN, USA?

United Airlines, Delta, and two other airlines fly from Portland International Airport (PDX) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, you can take a bus from Portland Curbside Bus Stop to Knoxville via Pasco Bus Stop, Denver Union Station, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 3d 13h.

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