There are 9 ways to get from Portland, ME to Buffalo by plane, bus (Amtrak, Greyhound), bus, train, car, bus (Amtrak, Flixbus), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Portland to Buffalo Niagara International Airport
best- Fly from Portland (PWM) to Buffalo Niagara International Airport (BUF)plane PWM - BUF
5h 48m$204–1,181Drive 508.3 mi
cheapest- Drive from Portland, ME to Buffalocar 508.3 mi
10h 20m$93–134Bus
- Take the bus from Portland, ME to Boston, MA - South Stationbus Portland / ...
- Take the bus from Boston to Buffalobus Greyhound US0171
13h$96–193Bus, train
- Take the bus from Portland, ME to Boston, MA - South Stationbus Portland / ...
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
15h 55m$160–418Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport
- Take the bus from Portland, ME to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
5h 39m$128–757Bus to Augusta State Airport, fly to Buffalo Niagara International Airport
- Take the bus from Portland Transportation Center to Augusta Transportation Centerbus
- Fly from Augusta State Airport (AUG) to Buffalo Niagara International Airport (BUF)plane AUG - BUF
7h 49m$129–690Bus to Boston Logan Airport, fly to Rochester, bus
- Take the bus from Portland, ME to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 57m$280–874Bus via Ithaca
- Take the bus from Portland, ME to Boston, MA - South Stationbus
- Take the bus from Boston to Ithacabus
- Take the bus from Ithaca to Buffalobus
15h 19m$94–228Train (Amtrak)
- Take the train from Portland to Bostontrain Downeaster
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
16h 57m$169–365
Portland, ME to Buffalo by bus
Questions & Answers
The cheapest way to get from Portland, ME to Buffalo is to drive which costs $90 - $140 and takes 10h 20m.
The fastest way to get from Portland, ME to Buffalo is to bus and fly which takes 5h 39m and costs $120 - $800.
No, there is no direct bus from Portland, ME to Buffalo. However, there are services departing from Portland, ME and arriving at Buffalo via Boston. The journey, including transfers, takes approximately 13h.
The distance between Portland, ME and Buffalo is 441 miles. The road distance is 511.2 miles.
The best way to get from Portland, ME to Buffalo without a car is to bus which takes 13h and costs $95 - $200.
It takes approximately 5h 48m to get from Portland, ME to Buffalo, including transfers.
Portland, ME to Buffalo bus services, operated by Concord Coach Lines, depart from Portland, ME station.
The best way to get from Portland, ME to Buffalo is to fly which takes 5h 48m and costs $200 - $1,200. Alternatively, you can bus, which costs $95 - $200 and takes 13h, you could also train, which costs $160 - $370 and takes 16h 57m.
Portland, ME to Buffalo bus services, operated by Concord Coach Lines, arrive at Boston, MA - South Station.
Yes, the driving distance between Portland, ME to Buffalo is 511 miles. It takes approximately 10h 20m to drive from Portland, ME to Buffalo.
What companies run services between Portland, ME, USA and Buffalo, NY, USA?
American Airlines, United Airlines, and three other airlines fly from Portland (PWM) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Portland, ME to Buffalo via Boston, MA - South Station and Boston in around 13h.
- Website
- aa.com
Flights from Portland to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 5h 12m
- When
- Monday to Saturday
- Estimated price
- $190–1,200
Flights from Portland to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $210–1,300
Flights from Portland to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h
- When
- Monday to Saturday
- Estimated price
- $240–1,400
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $100–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 50m
- When
- Monday to Thursday
- Estimated price
- $110–750
Flights from Augusta State Airport to Buffalo Niagara International Airport via Boston Logan Airport, New York La Guardia
- Ave. Duration
- 6h 35m
- When
- Monday to Thursday
- Estimated price
- $100–650
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $60–430
- Website
- jetblue.com
Flights from Portland to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,200
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $100–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $110–750
Flights from Augusta State Airport to Buffalo Niagara International Airport via Boston Logan Airport
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $95–600
Flights from Augusta State Airport to Buffalo Niagara International Airport via Boston Logan Airport, New York JFK
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $100–650
- Website
- united.com
Flights from Portland to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $200–1,200
Flights from Portland to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 3h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–460
- Website
- southwest.com
Flights from Portland to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 50m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $140–800
Flights from Augusta State Airport to Buffalo Niagara International Airport via Boston Logan Airport, Baltimore
- Ave. Duration
- 6h 52m
- When
- Tuesday and Wednesday
- Estimated price
- $120–700
- Website
- delta.com
Flights from Portland to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $200–1,200
Flights from Portland to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 21m
- When
- Monday to Saturday
- Estimated price
- $190–1,200
Flights from Portland to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $270–1,400
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 54m
- When
- Monday to Friday
- Estimated price
- $70–460
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $130–300
- Website
- https://www.amtrak.com/home.html
Train from Portland to Boston
- Ave. Duration
- 2h 32m
- Frequency
- Every 4 hours
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–30
- Website
- https://concordcoachlines.com
Bus from Portland, ME to Logan International Airport
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Bus from Portland Transportation Center to Augusta Transportation Center
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $13–17
- Website
- https://concordcoachlines.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
Bus from Portland Transportation Center to Augusta Transportation Center
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- $13–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $13–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–16
- Schedules at
- flixbus.com
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 5 times a week
- Estimated price
- $45–85
- Schedules at
- flixbus.com
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $28–100
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–95
- Flexible
- $55–100
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