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How to get fromPortland, ME to BuffaloBy plane, bus (Amtrak, Greyhound), bus, train, car, bus (Amtrak, Flixbus), or train (Amtrak)

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There are 9 ways to get from Portland, ME to Buffalo by plane, bus (Amtrak, Greyhound), bus, train, car, bus (Amtrak, Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Buffalo Niagara International Airport

    best
    1. Fly from Portland (PWM) to Buffalo Niagara International Airport (BUF)plane plane PWM - BUF
    5h 48m
    $204–1,181

  2. Drive 508.3 mi

    cheapest
    1. Drive from Portland, ME to Buffalocar car 508.3 mi
    10h 20m
    $93–134

  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h
    $96–193

  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    15h 55m
    $160–418

  5. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Portland, ME to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    5h 39m
    $128–757

  6. Bus to Augusta State Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Portland Transportation Center to Augusta Transportation Centerbus bus
    2. Fly from Augusta State Airport (AUG) to Buffalo Niagara International Airport (BUF)plane plane AUG - BUF
    7h 49m
    $129–690

  7. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Portland, ME to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 57m
    $280–874

  8. Bus via Ithaca

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    15h 19m
    $94–228

  9. Train (Amtrak)

    1. Take the train from Portland to Bostontrain train Downeaster
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 57m
    $169–365

Portland, ME to Buffalo by bus

Calendar7Weekly Buses
Duration13hAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

What companies run services between Portland, ME, USA and Buffalo, NY, USA?

American Airlines, United Airlines, and three other airlines fly from Portland (PWM) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Portland, ME to Buffalo via Boston, MA - South Station and Boston in around 13h.

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