There are 9 ways to get from Portland to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Portland to Charlotte  •  4 h 17 min

  1. Fly from Portland (PWM) to Charlotte (CLT) PWM - CLT

$229 - $735

Cheapest option

Bus Greyhound USA  •  21 h 50 min

  1. Take the bus from Portland, Me to Boston, Ma
  2. Take the bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal
  3. Take the bus from New York, Ny to Fayetteville, Nc
  4. Take the bus from Fayetteville, Nc to Florence, Sc

$107 - $277

7 alternative options

Fly Portland to Columbia  •  5 h 49 min

  1. Fly from Portland (PWM) to Columbia (CAE) PWM - CAE

$294 - $1,312

Fly Portland to Greenville/Spartanburg  •  5 h 35 min

  1. Fly from Portland (PWM) to Greenville/Spartanburg (GSP) PWM - GSP

$260 - $957

Fly Portland to Charleston  •  6 h 28 min

  1. Fly from Portland (PWM) to Charleston (CHS) PWM - CHS

$272 - $1,200

Bus to Boston, fly to Charleston  •  6 h 34 min

  1. Take the bus from Portland, ME to Logan Airport
  2. Fly from Boston (BOS) to Charleston (CHS) BOS - CHS

$145 - $493

Bus, train  •  19 h 25 min

  1. Take the bus from Portland, Me to Boston, Ma
  2. Take the train from Boston South Station to New York Penn Station
  3. Take the train from New York Penn Station to Florence Amtrak

$182 - $457

Bus Wanda Coach  •  20 h 43 min

  1. Take the bus from Portland, ME to Logan Airport
  2. Take the bus from Boston, MA to New York
  3. Take the bus from New York, NY to Florence, SC Nyc

$116 - $130

Drive  •  16 h 5 min

  1. Drive from Portland to Florence 952 miles

$90 - $140

Questions & Answers

No, there is no direct bus from Portland to South Carolina. However, there are services departing from Portland, Me and arriving at Florence, Sc via Boston, MA - South Station, New York, Ny and Fayetteville, Nc. The journey, including transfers, takes approximately 21 h 50 min.

More details

The distance between Portland and South Carolina is 885 miles. The road distance is 952 miles.

Get driving directions

The best way to get from Portland to South Carolina without a car is to bus and train which takes 19 h 25 min and costs .

More details

It takes approximately 4 h 17 min to get from Portland to South Carolina, including transfers.

More details

Portland to South Carolina bus services, operated by Greyhound USA, depart from Portland, Me station.

More details

The best way to get from Portland to South Carolina is to fly which takes 4 h 17 min and costs . Alternatively, you can bus, which costs and takes 20 h 43 min.

Mode details

The quickest flight from Portland Airport to Charlotte Airport is the direct flight which takes 2 h 28 min.

Search flights

Portland to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

More details

Yes, the driving distance between Portland to South Carolina is 952 miles. It takes approximately 16 h 5 min to drive from Portland to South Carolina.

Get driving directions

JetBlue Airways, American Airlines, United Airlines and Southwest Airlines offer flights from Portland Airport to Charlotte Airport.

Search flights

Map of how to get from Portland to South Carolina.
Launch map view
  • Distance: 884.9 miles
  • Duration: 4 h 17 min

What companies run services between Portland, ME, USA and South Carolina, USA?

American Airlines, United Airlines and three other airlines fly from Portland to Rock Hill hourly. Alternatively, you can take a bus from Portland to Florence via Logan Airport, Terminal A, South Station, Boston, MA, New York, New York, NY, and Florence, SC in around 20 h 43 min.

Airlines
American Airlines
Website
aa.com
Flights from Portland to Charlotte
Ave. Duration
2 h 34 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charlotte via Reagan Washington
Ave. Duration
4 h 30 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,300
Flights from Portland to Charlotte via Philadelphia
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Columbia via Charlotte
Ave. Duration
4 h 48 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Columbia via Philadelphia
Ave. Duration
4 h 39 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,300
Flights from Portland to Columbia via Reagan Washington
Ave. Duration
5 h 54 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,300
Flights from Portland to Columbia via Reagan Washington, Charlotte
Ave. Duration
6 h 21 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,300
Flights from Portland to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$240 - $1,100
Flights from Portland to Greenville/Spartanburg via Philadelphia
Ave. Duration
6 h 9 min
When
Every day
Estimated price
$240 - $1,100
Flights from Portland to Greenville/Spartanburg via Reagan Washington
Ave. Duration
7 h 27 min
When
Every day
Estimated price
$240 - $1,100
Flights from Portland to Charleston via Charlotte
Ave. Duration
4 h 48 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charleston via Reagan Washington
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charleston via Philadelphia
Ave. Duration
5 h 3 min
When
Every day
Estimated price
$290 - $1,300
Flights from Boston to Charleston via Charlotte
Ave. Duration
4 h 26 min
When
Every day
Estimated price
$150 - $1,100
United Airlines
Website
united.com
Flights from Portland to Charlotte via Washington Dulles
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$210 - $1,400
Flights from Portland to Columbia via Washington Dulles
Ave. Duration
5 h 51 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Columbia via Chicago O'Hare
Ave. Duration
7 h 40 min
When
Every day
Estimated price
$370 - $1,600
Flights from Portland to Greenville/Spartanburg via Washington Dulles
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$250 - $1,200
Flights from Portland to Greenville/Spartanburg via Newark
Ave. Duration
6 h 5 min
When
Every day
Estimated price
$250 - $1,200
Flights from Portland to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
7 h 45 min
When
Every day
Estimated price
$300 - $1,300
Flights from Portland to Charleston via Washington Dulles
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Charleston via Newark
Ave. Duration
5 h 23 min
When
Monday, Tuesday, Wednesday, Thursday and Saturday
Estimated price
$300 - $1,400
Flights from Boston to Charleston via Washington Dulles
Ave. Duration
4 h 13 min
When
Every day
Estimated price
$190 - $1,200
Flights from Boston to Charleston via Newark
Ave. Duration
4 h 19 min
When
Monday, Tuesday, Wednesday, Thursday and Saturday
Estimated price
$190 - $1,200
Southwest Airlines
Website
southwest.com
Flights from Portland to Charlotte via Baltimore
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$260 - $1,200
Flights from Portland to Charleston via Baltimore
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$320 - $1,300
Flights from Boston to Charleston via Baltimore
Ave. Duration
4 h 25 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$290 - $1,200
Delta
Website
delta.com
Flights from Portland to Columbia via Atlanta
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Columbia via New York La Guardia
Ave. Duration
5 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,300
Flights from Portland to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 21 min
When
Every day
Estimated price
$250 - $1,200
Flights from Portland to Greenville/Spartanburg via New York La Guardia
Ave. Duration
5 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,100
Flights from Portland to Greenville/Spartanburg via Atlanta
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$250 - $1,200
Flights from Portland to Charleston via Atlanta
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Charleston via New York La Guardia
Ave. Duration
5 h 11 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,300
Flights from Portland to Charleston via Detroit
Ave. Duration
5 h 39 min
When
Saturday
Estimated price
$310 - $1,400
Flights from Boston to Charleston
Ave. Duration
2 h 34 min
When
Every day
Estimated price
$180 - $1,200
JetBlue Airways
Website
jetblue.com
Flights from Portland to Charlotte via New York JFK
Ave. Duration
4 h 32 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$200 - $1,700
Flights from Portland to Charleston via New York JFK
Ave. Duration
5 h 3 min
When
Every day
Estimated price
$270 - $1,200
Flights from Boston to Charleston
Ave. Duration
2 h 28 min
When
Every day
Estimated price
$190 - $1,000
Flights from Boston to Charleston via Reagan Washington
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$190 - $1,000
Frontier Airlines
Website
flyfrontier.com
Flights from Portland to Greenville/Spartanburg via Orlando
Ave. Duration
8 h 39 min
When
Wednesday and Saturday
Estimated price
$230 - $950
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Boston South Station to New York Penn Station
Ave. Duration
3 h 42 min
Frequency
Hourly
Estimated price
$75 - $160
Website
amtrak.com
Coach
$75 - $160
Business Class
$110 - $200
First Class
$291
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Florence Amtrak
Ave. Duration
11 h 50 min
Frequency
Twice daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Bus operators
Concord Coach Lines
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Portland, Me to Boston, Ma
Ave. Duration
2 h 10 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Boston, Ma to New York, Ny
Ave. Duration
6 h 55 min
Frequency
Every 10 minutes
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from New York, Ny to Fayetteville, Nc
Ave. Duration
13 h 45 min
Frequency
Every 30 minutes
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
Every 30 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35
Lucky Star Bus
Phone
(888) 881-0887 / (617) 269-5468
Email
info@luckystarbus.com
Website
luckystarbus.com
Bus from Boston, MA to New York
Ave. Duration
4 h 30 min
Frequency
Every 2 hours
Estimated price
$25
Schedules at
luckystarbus.com
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Florence, SC
Ave. Duration
11 h 45 min
Frequency
5 times a day
Estimated price
$55
Schedules at
wandacoach.com
Starline Bus
Website
starlinebus.com
Bus from New York, NY to Florence, SC
Ave. Duration
11 h 15 min
Frequency
Twice daily
Estimated price
$55
Schedules at
starlinebus.com
Book at
gotobus.com
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal
Ave. Duration
3 h 45 min
Frequency
Hourly
Estimated price
$21 - $40
Website
peterpanbus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

More details

The best way to get from Portland to Portland Airport is to line 5 bus which takes 16 min and costs .

More details