There are 5 ways to get from Portland to Hyannis by bus, train, car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Recommended option
Bus Greyhound USA • 4 h 14 min
$36 - $64
4 alternative options
Bus Concord Coach Lines • 4 h 30 min
$40 - $56
Train, bus • 4 h 54 min
$54 - $99
Drive • 3 h 19 min
$17 - $26
Bus, fly • 4 h 53 min
$107 - $300
What companies run services between Portland, ME, USA and Hyannis, MA, USA?
You can take a bus from Portland to Hyannis via Boston, Ma and Boston, MA - South Station Transp. Center in around 4 h 14 min.

- Website
- capeair.com
Flights from Boston to Hyannis
- Ave. Duration
- 35 min
- When
- Monday, Tuesday, Wednesday, Friday, Saturday and Sunday
- Estimated price
- $100 - $550
Flights from Boston to Hyannis via Nantucket
- Ave. Duration
- 2 h 1 min
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $100 - $550

- Phone
- +1 1-800-872-7245
- Website
- amtrak.com
Train from Portland Transportation Center Amtrak to Boston North Station Amtrak
- Ave. Duration
- 2 h 30 min
- Frequency
- Every 4 hours
- Estimated price
- $30 - $70
- Website
- amtrak.com
- Coach Seat
- $30 - $50
- Flexi Coach Seat
- $55 - $80
- Business Coach Seat
- $50 - $70
- Room
- $160 - $230

- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Portland, Me to Boston, Ma
- Ave. Duration
- 2 h 10 min
- Frequency
- Hourly
- Estimated price
- $16 - $40
- Website
- greyhound.com
- Economy
- $16 - $25
- Flexible
- $29 - $40

- Website
- concordcoachlines.com
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 2 h 10 min
- Frequency
- Twice daily
- Estimated price
- $20 - $28
- Schedules at
- concordcoachlines.com
- Book at
- webstore.concordcoachlines.com
Bus from Portland, ME to Logan Airport
- Ave. Duration
- 1 h 55 min
- Frequency
- Hourly
- Estimated price
- $20 - $28
- Schedules at
- concordcoachlines.com
- Book at
- webstore.concordcoachlines.com

- Website
- p-b.com
Bus from Boston, MA - South Station Transp. Center to Hyannis, MA - Hyannis Transportation Center
- Ave. Duration
- 1 h 30 min
- Frequency
- Hourly
- Estimated price
- $19 - $27
- Schedules at
- p-b.com
Bus from Logan International Airport to Hyannis, MA - Hyannis Transportation Center
- Ave. Duration
- 1 h 50 min
- Frequency
- Hourly
- Estimated price
- $20 - $28
- Schedules at
- p-b.com
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Questions & Answers
How far is it from Portland to Hyannis?
The distance between Portland and Hyannis is 224 km. The road distance is 286 km.
What is the cheapest way to get from Portland to Hyannis?
The cheapest way to get from Portland to Hyannis is to drive which costs $17 - $26 and takes 3 h 19 min.
What is the fastest way to get from Portland to Hyannis?
The quickest way to get from Portland to Hyannis is to drive which takes 3 h 19 min and costs $17 - $26.
Is there a direct bus between Portland and Hyannis?
No, there is no direct bus from Portland to Hyannis. However, there are services departing from Portland, Me and arriving at Hyannis, MA - Hyannis Transportation Center via Boston, MA - South Station Transp. Center. The journey, including transfers, takes approximately 4 h 14 min.
How long does it take to get from Portland to Hyannis?
It takes approximately 4 h 14 min to get from Portland to Hyannis, including transfers.