There are 9 ways to get from Port St. Lucie to North Carolina by bus, plane, shuttle, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to West Palm Beach/Palm Beach, fly to Charlotte  •  4 h 26 min

  1. Take the bus from Fort Pierce to West Palm Beach
  2. Fly from West Palm Beach/Palm Beach (PBI) to Charlotte (CLT) PBI - CLT

$198 - $465

Cheapest option

Bus via Savannah, Ga  •  18 h 21 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter 209 / ...
  2. Take the bus from Orlando, Fl to Savannah, Ga
  3. Take the bus from Savannah, Ga to Charlotte, Nc

$99 - $241

7 alternative options

Shuttle to Orlando, fly to Charlotte  •  5 h 29 min

  1. Take a shuttle bus from Port St. Lucie, FL - Sunoco to Orlando Airport
  2. Fly from Orlando (MCO) to Charlotte (CLT) MCO - CLT

$160 - $436

Bus, bus to Fort Lauderdale, fly to Charlotte  •  5 h 53 min

  1. Take the bus from Fort Pierce to West Palm Beach
  2. Take the bus from West Palm Beach to Fort Lauderdale
  3. Fly from Fort Lauderdale (FLL) to Charlotte (CLT) FLL - CLT

$193 - $455

Bus to Melbourne, fly to Charlotte  •  6 h 25 min

  1. Take the bus from Ft Pierce, Fl to Melbourne, Fl
  2. Fly from Melbourne (MLB) to Charlotte (CLT) MLB - CLT

$257 - $671

Bus to West Palm Beach/Palm Beach, fly to Raleigh/Durham  •  6 h 24 min

  1. Take the bus from Fort Pierce to West Palm Beach
  2. Fly from West Palm Beach/Palm Beach (PBI) to Raleigh/Durham (RDU) PBI - RDU

$116 - $399

Bus La Cubana  •  14 h 20 min

  1. Take the bus from Fort Pierce to Ocala RedCoach
  2. Take the bus from Ocala, FL to Charlotte, NC Atlanta route

$215 - $234

Bus, train  •  16 h 56 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter 209 / ...
  2. Take the train from Orlando Amtrak to Savannah Amtrak
  3. Take the bus from Savannah, Ga to Charlotte, Nc

$111 - $280

Drive  •  10 h 12 min

  1. Drive from Port St. Lucie to Charlotte 621.8 miles

$60 - $90

Questions & Answers

No, there is no direct bus from Port St. Lucie to North Carolina. However, there are services departing from Port St Lucie, FL - Travel Plaza and arriving at Charlotte, Nc via Bill Beck Blvd And E. Osceola Pkwy, Kissimmee, Fl, Orlando, Fl and Savannah, Ga. The journey, including transfers, takes approximately 18 h 21 min.

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The distance between Port St. Lucie and North Carolina is 587 miles. The road distance is 621.8 miles.

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The best way to get from Port St. Lucie to North Carolina without a car is to bus which takes 14 h 20 min and costs .

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It takes approximately 4 h 26 min to get from Port St. Lucie to North Carolina, including transfers.

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Port St. Lucie to North Carolina bus services, operated by The Florida Express Bus, depart from Port St Lucie, FL - Travel Plaza station.

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The quickest flight from West Palm Beach/Palm Beach Airport to Charlotte Airport is the direct flight which takes 1 h 53 min.

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Port St. Lucie to North Carolina bus services, operated by Greyhound USA, arrive at Charlotte, Nc station.

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Yes, the driving distance between Port St. Lucie to North Carolina is 622 miles. It takes approximately 10 h 12 min to drive from Port St. Lucie to North Carolina.

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American Airlines and Delta offer flights from West Palm Beach/Palm Beach Airport to Charlotte Airport.

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There are 10+ hotels available in North Carolina. Prices start at $100 USD per night.

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Map of how to get from Port St. Lucie to North Carolina.
Launch map view
  • Distance: 587.5 miles
  • Duration: 4 h 26 min

What companies run services between Port St. Lucie, FL, USA and North Carolina, USA?

You can take a bus from Port St. Lucie to Charlotte via Ocala, Ocala, FL, and Charlotte, NC in around 14 h 20 min.

Airlines
Delta
Website
delta.com
Flights from West Palm Beach/Palm Beach to Charlotte via Atlanta
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$170 - $700
Flights from Orlando to Charlotte via Atlanta
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$160 - $850
Flights from Fort Lauderdale to Charlotte via Atlanta
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$160 - $650
Flights from Melbourne to Charlotte via Atlanta
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$260 - $1,100
Flights from West Palm Beach/Palm Beach to Raleigh/Durham via Atlanta
Ave. Duration
4 h 19 min
When
Every day
Estimated price
$110 - $600
American Airlines
Website
aa.com
Flights from West Palm Beach/Palm Beach to Charlotte
Ave. Duration
1 h 56 min
When
Every day
Estimated price
$280 - $750
Flights from Orlando to Charlotte
Ave. Duration
1 h 43 min
When
Every day
Estimated price
$170 - $700
Flights from Fort Lauderdale to Charlotte
Ave. Duration
2 h 6 min
When
Every day
Estimated price
$270 - $750
Flights from Melbourne to Charlotte
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$400 - $1,100
Flights from West Palm Beach/Palm Beach to Raleigh/Durham via Charlotte
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$110 - $550
Southwest Airlines
Website
southwest.com
Flights from Fort Lauderdale to Charlotte via Nashville
Ave. Duration
4 h 30 min
When
Sunday
Estimated price
$260 - $700
Flights from Fort Lauderdale to Charlotte via Baltimore
Ave. Duration
4 h 45 min
When
Monday to Friday
Estimated price
$260 - $700
Flights from West Palm Beach/Palm Beach to Raleigh/Durham via Atlanta
Ave. Duration
4 h 15 min
When
Monday to Saturday
Estimated price
$140 - $600
Flights from West Palm Beach/Palm Beach to Raleigh/Durham via Baltimore
Ave. Duration
4 h 25 min
When
Monday to Friday
Estimated price
$150 - $600
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to Charlotte
Ave. Duration
1 h 47 min
When
Monday, Wednesday, Friday and Saturday
Estimated price
$65 - $700
Flights from West Palm Beach/Palm Beach to Raleigh/Durham
Ave. Duration
2 h 5 min
When
Tuesday, Thursday and Sunday
Estimated price
$65 - $310
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Orlando Amtrak to Savannah Amtrak
Ave. Duration
5 h 44 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $140
Business Coach Seat
$95 - $140
Room
$240 - $330
Bus operators
Red Coach
Phone
+1 877 733 0724
Email
webtickets@redcoachusa.com
Website
redcoachusa.com
Bus from Fort Pierce to West Palm Beach
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$26 - $40
Book at
redcoachusa.com
First Class
$35 - $55
Business
$26 - $40
Bus from West Palm Beach to Fort Lauderdale
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$25 - $35
Book at
redcoachusa.com
First Class
$35 - $55
Business
$25 - $35
Bus from Fort Pierce to Ocala
Ave. Duration
3 h 15 min
Frequency
Hourly
Estimated price
$40 - $60
Book at
redcoachusa.com
First Class
$50 - $75
Business
$40 - $60
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Port St Lucie, FL - Travel Plaza to West Palm Beach - Travel Plaza
Ave. Duration
45 min
Frequency
Every 4 hours
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter
Ave. Duration
1 h 30 min
Frequency
Every 4 hours
Estimated price
$27 - $60
More information at
American Bus Tickets
Smart Shuttle Line, Inc.
Phone
772-343-0217
Email
smartshuttleline@hotmail.com
Website
smartshuttleline.com
Shuttle from Port St. Lucie, FL - Sunoco to Orlando Airport
Ave. Duration
2 h 18 min
Frequency
5 times a day
Estimated price
$84
Schedules at
smartshuttleline.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Pierce, Fl to Melbourne, Fl
Ave. Duration
1 h 10 min
Frequency
Every 30 minutes
Estimated price
$12 - $27
Website
greyhound.com
Economy
$12 - $17
Flexible
$21 - $27
Bus from Savannah, Ga to Charlotte, Nc
Ave. Duration
6 h 10 min
Frequency
Every 30 minutes
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75
Bus from Orlando, Fl to Savannah, Ga
Ave. Duration
7 h 40 min
Frequency
Every 15 minutes
Estimated price
$30 - $85
Website
greyhound.com
Economy
$30 - $55
Flexible
$60 - $85
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from Fort Pierce, FL - Love's to Melbourne, FL - Waffle House
Ave. Duration
55 min
Frequency
4 times a day
Estimated price
$49
Schedules at
javaxbus.com
Book at
gotobus.com
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Ocala, FL to Charlotte, NC
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$159
Schedules at
lacubanabus.com

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More Questions & Answers

The best way to get from Port St. Lucie to Orlando Airport is to shuttle which takes 2 h 18 min and costs .

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