There are 9 ways to get from Port St. Lucie to North Carolina by bus, plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to West Palm Beach/Palm Beach, fly to Charlotte  •  4 h 44 min

  1. Take the bus from Port St. Lucie - Wendy's to West Palm Beach Airport
  2. Fly from West Palm Beach/Palm Beach (PBI) to Charlotte (CLT) PBI - CLT

$212 - $445

Cheapest option

Bus Greyhound USA  •  16 h

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter 209 / ...
  2. Take the bus from Orlando, Fl to Jacksonville, Fl
  3. Take the bus from Jacksonville, Fl to Charlotte, Nc

$91 - $241

7 alternative options

Bus to Fort Lauderdale, fly to Charlotte  •  5 h 29 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Fort Lauderdale, FL - Tri-Rail Station
  2. Fly from Fort Lauderdale (FLL) to Charlotte (CLT) FLL - CLT

$168 - $421

Bus to Miami, fly to Charlotte  •  5 h 56 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Miami Airport
  2. Fly from Miami (MIA) to Charlotte (CLT) MIA - CLT

$168 - $511

Fly Orlando to Raleigh/Durham, line 300 bus  •  6 h 52 min

  1. Fly from Orlando (MCO) to Raleigh/Durham (RDU) MCO - RDU
  2. Take the line 300 bus from Regional Transit Center to N Harrison Ave at W Johnson St

$168 - $740

Bus, train via Savannah, Ga  •  17 h 43 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter 209 / ...
  2. Take the train from Kissimmee Amtrak to Savannah Amtrak
  3. Take the bus from Savannah, Ga to Charlotte, Nc

$105 - $279

Bus, train  •  21 h 7 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter 209 / ...
  2. Take the train from Kissimmee Amtrak to Cary Amtrak
  3. Take the train from Cary Amtrak to Charlotte Amtrak

$155 - $421

Bus La Cubana  •  21 h 23 min

  1. Take the bus from Port St Lucie, FL - Travel Plaza to Miami 1100 / ...
  2. Take the bus from Miami Beach, FL to Charlotte, NC Atlanta route

$152 - $237

Drive  •  10 h 12 min

  1. Drive from Port St. Lucie to Charlotte 621.8 miles

$60 - $90

Questions & Answers

The cheapest way to get from Port St. Lucie to North Carolina is to drive which costs $60 - $90 and takes 10 h 12 min.

More details

The quickest way to get from Port St. Lucie to North Carolina is to bus and fly which costs $210 - $450 and takes 4 h 44 min.

More details

The distance between Port St. Lucie and North Carolina is 587 miles. The road distance is 621.8 miles.

Get driving directions

It takes approximately 4 h 44 min to get from Port St. Lucie to North Carolina, including transfers.

More details

No, there is no direct bus from Port St. Lucie to North Carolina. However, there are services departing from Port St Lucie, FL - Travel Plaza and arriving at Charlotte, Nc via Bill Beck Blvd And E. Osceola Pkwy, Kissimmee, Fl, Orlando, Fl and Jacksonville, Fl. The journey, including transfers, takes approximately 16 h.

More details

What companies run services between Port St. Lucie, FL, USA and North Carolina, USA?

You can take a bus from Port St. Lucie to Charlotte via Kissimmee, FL - Walmart Supercenter, Bill Beck Blvd And E. Osceola Pkwy, Lynx Kissimmee Intermodal Station, Kissimmee, Fl, Orlando, Fl, and Jacksonville, Fl in around 16 h.

Airlines
American Airlines
Website
aa.com
Flights from West Palm Beach/Palm Beach to Charlotte
Ave. Duration
2 h 1 min
When
Every day
Estimated price
$280 - $750
Flights from Fort Lauderdale to Charlotte
Ave. Duration
2 h 10 min
When
Every day
Estimated price
$270 - $750
Flights from Miami to Charlotte
Ave. Duration
2 h 13 min
When
Every day
Estimated price
$210 - $650
Flights from Miami to Charlotte via Marsh Harbour
Ave. Duration
3 h 49 min
When
Saturday
Estimated price
$210 - $650
Flights from Miami to Charlotte via Charleston
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$210 - $650
Flights from Miami to Charlotte via Jacksonville
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$210 - $650
Flights from Miami to Charlotte via North Eleuthera
Ave. Duration
4 h 1 min
When
Saturday
Estimated price
$210 - $650
Flights from Miami to Charlotte via Tallahassee
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $650
Flights from Orlando to Raleigh/Durham via Charlotte
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$160 - $1,100
Delta
Website
delta.com
Flights from West Palm Beach/Palm Beach to Charlotte via Atlanta
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$170 - $700
Flights from Fort Lauderdale to Charlotte via Atlanta
Ave. Duration
4 h 24 min
When
Every day
Estimated price
$160 - $650
Flights from Orlando to Raleigh/Durham
Ave. Duration
1 h 54 min
When
Every day
Estimated price
$160 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Fort Lauderdale to Charlotte via Baltimore
Ave. Duration
4 h 45 min
When
Monday to Friday
Estimated price
$260 - $700
Flights from Orlando to Raleigh/Durham
Ave. Duration
1 h 42 min
When
Every day
Estimated price
$210 - $1,100
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to Raleigh/Durham
Ave. Duration
1 h 46 min
When
Tuesday, Thursday and Sunday
Estimated price
$85 - $750
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kissimmee Amtrak to Savannah Amtrak
Ave. Duration
6 h 27 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$95 - $140
Business Coach Seat
$100 - $140
Room
$240 - $340
Train from Kissimmee Amtrak to Cary Amtrak
Ave. Duration
13 h 20 min
Frequency
Once daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $240
Business Coach Seat
$180 - $260
Room
$380 - $550
Train from Cary Amtrak to Charlotte Amtrak
Ave. Duration
2 h 58 min
Frequency
4 times a day
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $90
Room
$180 - $260
Bus operators
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from Port St. Lucie - Wendy's to West Palm Beach Airport
Ave. Duration
1 h 2 min
Frequency
Every 2 hours
Estimated price
$49
Schedules at
javaxbus.com
Book at
gotobus.com
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Port St Lucie, FL - Travel Plaza to Fort Lauderdale, FL - Tri-Rail Station
Ave. Duration
1 h 35 min
Frequency
Every 4 hours
Estimated price
$27 - $60
Schedules at
webstore.thefloridaexpressbus.com
Book at
busticketreservations.com
Bus from Port St Lucie, FL - Travel Plaza to Miami Airport
Ave. Duration
2 h 15 min
Frequency
Twice daily
Estimated price
$27 - $60
Schedules at
webstore.thefloridaexpressbus.com
Book at
busticketreservations.com
Bus from Port St Lucie, FL - Travel Plaza to Kissimmee, FL - Walmart Supercenter
Ave. Duration
1 h 30 min
Frequency
Every 4 hours
Estimated price
$27 - $60
Schedules at
webstore.thefloridaexpressbus.com
Book at
busticketreservations.com
Bus from Port St Lucie, FL - Travel Plaza to Miami
Ave. Duration
2 h 25 min
Frequency
5 times a day
Estimated price
$27 - $60
Schedules at
webstore.thefloridaexpressbus.com
Book at
busticketreservations.com
Go Triangle
Phone
+1 919-485-7433
Email
customerservice@gotriangle.org
Website
gotriangle.org
Bus from Regional Transit Center to N Harrison Ave at W Johnson St
Ave. Duration
32 min
Frequency
Every 3 hours
Estimated price
$2 - $3
Schedules at
gotriangle.org
Jet Set Express
Phone
(+1) 407 649 4994
Email
tours@jetsetusa.com
Website
miamiorlando.com
Bus from Fort Pierce to Kissimmee, FL - Walmart Supercenter
Ave. Duration
1 h 45 min
Frequency
Twice daily
Estimated price
$20
Schedules at
miamiorlando.com
Book at
gotobus.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Jacksonville, Fl
Ave. Duration
2 h 30 min
Frequency
Every 30 minutes
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Jacksonville, Fl to Charlotte, Nc
Ave. Duration
9 h
Frequency
Every 30 minutes
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Savannah, Ga to Charlotte, Nc
Ave. Duration
6 h 10 min
Frequency
Every 30 minutes
Estimated price
$30 - $75
Website
greyhound.com
Economy
$30 - $50
Flexible
$55 - $75
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Miami Beach, FL to Charlotte, NC
Ave. Duration
17 h 20 min
Frequency
Once daily
Estimated price
$110 - $160
Schedules at
lacubanabus.com

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