Travel from Port-St-Lucie to Key-West

Bus from Port St. Lucie to Key West

Jet Set Bus operates a bus from Port St. Lucie to Key West 3 times a day. Tickets cost $20 and the journey takes 2 h 30 min. Go Buses also services this route twice daily.

Travel Guides

Need to know: GreyhoundRome2rio’s guide on the bus operator has all the information you need

How to get from Port St. Lucie to Key West

From Port St Lucie bus to Miami, FL then bus to Key West, FL. 7 h 15 min $45. From Port St Lucie, FL - Travel Plaza bus to Miami International Airport, walk to Miami, bus to Airport/Beaches, then bus to Flagler & Grinnell. 9 h 8 min $50. From Port St. Lucie drive to Key West. 5 h 20 min $32. From Port St. Lucie, FL - Sunoco shuttle to Orlando airport, fly to Key West airport, then bus to Key West. 5 h 57 min $219. From Port St Lucie bus to Sheridan Street Station, walk to Fort Lauderdale, FL, bus to Miami airport, fly to Key West airport, then bus to Key West. 5 h 34 min $283. From Fort Pierce bus to West Palm Beach, FL, bus to Fort Lauderdale airport, fly to Key West airport, then bus to Key West. 5 h 47 min $196.
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  1. Here are 6 options to get from
    Port St. Lucie to Key West:

    1. Trip:
      1 Bus Go Buses
      • One-Way approx: USD $45
      • Duration: 7 h 15 min
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      • Trip:
        1 Bus Go Buses
        • One-Way approx: USD $45
        • Duration: 7 h 15 min
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    2. Trip:
      2 Bus Greyhound USA
      • One-Way approx: USD $36 - $79
      • Duration: 9 h 8 min
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      • Trip:
        2 Bus Greyhound USA
        • One-Way approx: USD $36 - $79
        • Duration: 9 h 8 min
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    3. Trip:
      3 Drive
      • One-Way approx: USD $26 - $40
      • Duration: 5 h 20 min
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      • Trip:
        3 Drive
        • One-Way approx: USD $26 - $40
        • Duration: 5 h 20 min
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    4. Trip:
      4 Shuttle to Orlando, fly
      • One-Way approx: USD $177 - $499
      • Duration: 5 h 57 min
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      • Trip:
        4 Shuttle to Orlando, fly
        • One-Way approx: USD $177 - $499
        • Duration: 5 h 57 min
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    5. Trip:
      5 Bus to Miami, fly
      • One-Way approx: USD $171 - $463
      • Duration: 5 h 34 min
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      • Trip:
        5 Bus to Miami, fly
        • One-Way approx: USD $171 - $463
        • Duration: 5 h 34 min
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    6. Trip:
      6 Bus, bus to Fort Lauderdale, fly
      • One-Way approx: USD $128 - $397
      • Duration: 5 h 47 min
      Open +
      • Trip:
        6 Bus, bus to Fort Lauderdale, fly
        • One-Way approx: USD $128 - $397
        • Duration: 5 h 47 min
        Close x