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How to get fromPort Saint Lucie to Appletonby car, plane, bus (Flixbus, Greyhound), bus, train, or taxi

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There are 8 ways to get from Port Saint Lucie to Appleton by car, plane, bus (Flixbus, Greyhound), bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Appleton International Airport

    best
    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Appleton International Airport (ATW)plane plane SFB - ATW
    5h 37m
    $133–533

  2. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Oshkoshbus bus
    33h 6m
    $289–462

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Oshkoshbus bus
    2d 1h
    $1,042–1,699

  4. Drive  1,409.6 mi

    1. Drive from Port Saint Lucie to Appletoncar car 1,409.6 mi
    24h 55m
    $258–372

  5. Bus to Orlando, fly to Appleton International Airport

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Appleton International Airport (ATW)plane plane MCO - ATW
    7h 31m
    $143–531

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Appleton International Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Appleton International Airport (ATW)plane plane FLL - ATW
    7h 9m
    $165–661

  7. Bus, taxi to Melbourne International Airport, fly to Appleton International Airport

    1. Take the bus from Fort Pierce to Sebastianbus bus
    2. Take the taxi from Sebastian to Melbourne International Airport (MLB)taxi taxi
    3. Fly from Melbourne International Airport (MLB) to Appleton International Airport (ATW)plane plane MLB - ATW
    14h 6m
    $204–636

  8. Bus to Orlando, fly to General Mitchell International Airport, bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    3. Take the bus from Milwaukee to Oshkoshbus bus
    10h 37m
    $510–1,227

Orlando Sanford (SFB) to Appleton International Airport (ATW) flights

Calendar5Weekly Planes
Duration3h 28mAverage Duration
Ticket$99Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Saint Lucie to Appleton.ExpandLaunch map view
  • Distance: 1,278.8 mi
  • Duration: 5h 37m

What companies run services between Port Saint Lucie, FL, USA and Appleton, WI, USA?

You can take a vehicle from Port Saint Lucie to Appleton via Port St Lucie, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Oshkosh in around 33h 6m.

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