Rome2Rio

How to get fromPort Saint Lucie to Appletonby bus, plane, bus (Flixbus, Greyhound), train or car

Find Transport to Appleton

See all options

There are 7 ways to get from Port Saint Lucie to Appleton by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly

    best
    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Appleton International Airport (ATW)plane plane FLL - ATW
    6h 27m
    $116–516

  2. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    31h 10m
    $185–352

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    2d 1h
    $311–576

  4. Drive 1,414.1 mi

    1. Drive from Port Saint Lucie to Appletoncar car 1,414.1 mi
    24h 47m
    $259–373

  5. Drive to Orlando Sanford, fly

    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Appleton International Airport (ATW)plane plane SFB - ATW
    5h 46m
    $133–508

  6. Bus to Orlando, fly

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Appleton International Airport (ATW)plane plane MCO - ATW
    7h 35m
    $127–436

  7. Bus to Palm Beach International Airport, fly

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from Palm Beach International Airport (PBI) to Appleton International Airport (ATW)plane plane PBI - ATW
    8h 53m
    $158–727

Port Saint Lucie to Appleton by bus, train, and foot

Calendar5Weekly Services
Duration2d 1hAverage Duration
Ticket$311Cheapest Price
See schedules

Questions & Answers

What companies run services between Port Saint Lucie, FL, USA and Appleton, WI, USA?

You can take a vehicle from Port Saint Lucie to Appleton Transit Center via Port St Lucie, Atlanta Bus Station, and Chicago Bus Station in around 31h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Port Saint Lucie

Trips to Appleton

Popular routes