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How to get fromPort Isabel to Destinby plane, bus, taxi, train or car

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There are 9 ways to get from Port Isabel to Destin by plane, bus, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Brownsville-South Padre Island International Airport to Destin–Fort Walton Beach Airport

    best
    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Destin–Fort Walton Beach Airport (VPS)plane plane BRO - VPS
    6h 53m
    $152–607

  2. Bus, taxi

    1. Take the bus from Brownsville Bus Station to Houston - Harrisburg Blvdbus bus
    2. Take the bus from Houston - Harrisburg Blvd to Crestviewbus bus
    3. Take the taxi from Crestview to Destintaxi taxi
    20h 34m
    $257–337

  3. Bus, train, taxi

    1. Take the bus from Brownsville to San Antoniobus bus
    2. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    4. Take the bus from Biloxi to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    30h 56m
    $302–473

  4. Drive 933.4 mi

    1. Drive from Port Isabel to Destincar car 933.4 mi
    16h 59m
    $171–246

  5. Fly Brownsville-South Padre Island International Airport to Pensacola International Airport, taxi

    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Pensacola International Airport (PNS)plane plane BRO - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    7h 43m
    $232–762

  6. Fly Brownsville-South Padre Island International Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Northwest Florida Beaches International Airport (ECP)plane plane BRO - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    7h 19m
    $212–642

  7. Bus to Rio Grande Valley International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Brownsville to Harlingen Bus Stationbus bus
    2. Fly from Rio Grande Valley International Airport (HRL) to Destin–Fort Walton Beach Airport (VPS)plane plane HRL - VPS
    9h 56m
    $154–509

  8. Bus, taxi via Houston

    1. Take the bus from La Plaza at Brownsville to Houston Bus Stationbus bus
    2. Take the bus from Houston - Harrisburg Blvd to Crestviewbus bus
    3. Take the taxi from Crestview to Destintaxi taxi
    21h 39m
    $227–337

  9. Bus, taxi via Crestview

    1. Take the bus from Matamoros to Houstonbus bus
    2. Take the bus from Houston to McDonald's - Crestviewbus bus
    3. Take the taxi from McDonald's - Crestview to Destintaxi taxi
    26h 28m
    $250–422

Brownsville-South Padre Island International Airport (BRO) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar28Weekly Planes
Duration7h 42mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

What companies run services between Port Isabel, TX, USA and Destin, FL, USA?

American Airlines flies from Brownsville-South Padre Island International Airport (BRO) to Destin–Fort Walton Beach Airport (VPS) 4 times a day.

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