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How to get fromPort Isabel to Destinby plane, bus, taxi, train or car

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There are 11 ways to get from Port Isabel to Destin by plane, bus, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Brownsville-South Padre Island International Airport to Destin–Fort Walton Beach Airport

    best
    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Destin–Fort Walton Beach Airport (VPS)planeBRO - VPS
    6h 46m
    $142–607

  2. Bus, taxi

    1. Take the bus from Brownsville Bus Station to Houston - Harrisburg Blvdbus
    2. Take the bus from Houston - Harrisburg Blvd to Crestviewbus
    3. Take the taxi from Crestview to Destintaxi
    20h 34m
    $257–337

  3. Bus, train, taxi

    1. Take the bus from Brownsville to San Antoniobus
    2. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain
    3. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus
    4. Take the bus from Biloxi to Crestviewbus
    5. Take the taxi from Crestview to Destintaxi
    30h 55m
    $303–502

  4. Drive 933.4 mi

    1. Drive from Port Isabel to Destincar933.4 mi
    16h 54m
    $171–246

  5. Fly Brownsville-South Padre Island International Airport to Pensacola International Airport, taxi

    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Pensacola International Airport (PNS)planeBRO - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi
    6h 57m
    $222–762

  6. Fly Brownsville-South Padre Island International Airport to Northwest Florida Beaches International Airport, taxi

    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Northwest Florida Beaches International Airport (ECP)planeBRO - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi
    6h 51m
    $212–632

  7. Bus to Rio Grande Valley International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Brownsville to Harlingen Bus Stationbus
    2. Fly from Rio Grande Valley International Airport (HRL) to Destin–Fort Walton Beach Airport (VPS)planeHRL - VPS
    10h
    $154–509

  8. Bus to Rio Grande Valley International Airport, fly to Pensacola International Airport, taxi

    1. Take the bus from Brownsville to Harlingen Bus Stationbus
    2. Fly from Rio Grande Valley International Airport (HRL) to Pensacola International Airport (PNS)planeHRL - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi
    9h 59m
    $249–694

  9. Bus to Rio Grande Valley International Airport, fly to Northwest Florida Beaches International Airport, taxi

    1. Take the bus from Brownsville to Harlingen Bus Stationbus
    2. Fly from Rio Grande Valley International Airport (HRL) to Northwest Florida Beaches International Airport (ECP)planeHRL - ECP
    3. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi
    10h 6m
    $234–614

  10. Bus, taxi via Houston

    1. Take the bus from La Plaza at Brownsville to Houston Bus Stationbus
    2. Take the bus from Houston - Harrisburg Blvd to Crestviewbus
    3. Take the taxi from Crestview to Destintaxi
    21h 39m
    $227–337

  11. Bus, taxi via Crestview

    1. Take the bus from Matamoros to Houstonbus
    2. Take the bus from Houston to McDonald's - Crestviewbus
    3. Take the taxi from McDonald's - Crestview to Destintaxi
    26h 28m
    $250–422

Brownsville-South Padre Island International Airport (BRO) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar20Weekly Planes
Duration6h 2mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

What companies run services between Port Isabel, TX, USA and Destin, FL, USA?

American Airlines flies from Brownsville-South Padre Island International Airport (BRO) to Destin–Fort Walton Beach Airport (VPS) 3 times a day.

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