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How to get fromPoplar Bluff to Key Westby car, plane, bus, train or ferry

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There are 7 ways to get from Poplar Bluff to Key West by car, plane, bus, train, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Barkley Regional Airport, fly

    best
    1. Drive from Poplar Bluff to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Key West International Airport (EYW)plane plane PAH - EYW
    7h 45m
    $280–1,240
  2. Drive to Mc Kellar-Sipes Regional Airport, fly

    cheapest
    1. Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car car
    2. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Key West International Airport (EYW)plane plane MKL - EYW
    7h 45m
    $136–599
  3. Drive, bus

    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    35h 12m
    $191–508
  4. Drive 1,231.2 mi

    1. Drive from Poplar Bluff to Key Westcar car 1,231.2 mi
    23h 35m
    $225–325
  5. Train to Lambert–St. Louis International Airport, fly

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane plane STL - EYW
    10h 54m
    $212–959
  6. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    38h 12m
    $161–437
  7. Train, bus, ferry

    1. Take the train from Poplar Bluff Station to Longviewtrain train
    2. Take the bus from Longview Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    42h 6m
    $404–691

Poplar Bluff to Key West by train, bus, and foot

Calendar7Weekly Services
Duration38h 12mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

What companies run services between Poplar Bluff, MO, USA and Key West, FL, USA?

There is no direct connection from Poplar Bluff to Key West. However, you can drive to Barkley Regional Airport (PAH) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a vehicle from Poplar Bluff to N Roosevelt & 3rd Street via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 35h 12m.

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