Rome2Rio

How to get fromPoplar Bluff to Key Westby train, plane, car, bus, taxi or ferry

Find Transport to Key West

See all options

There are 8 ways to get from Poplar Bluff to Key West by train, plane, car, bus, taxi, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Lambert–St. Louis International Airport, fly

    best
    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane plane STL - EYW
    10h 56m
    $213–1,000

  2. Drive to Mc Kellar-Sipes Regional Airport, fly

    cheapest
    1. Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car car
    2. Fly from Mc Kellar-Sipes Regional Airport (MKL) to Key West International Airport (EYW)plane plane MKL - EYW
    7h 46m
    $136–599

  3. Drive, bus

    1. Drive from Poplar Bluff to Cape Girardeaucar car
    2. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    34h 37m
    $171–437

  4. Drive 1,231.4 mi

    1. Drive from Poplar Bluff to Key Westcar car 1,231.4 mi
    23h 46m
    $225–325

  5. Drive to Cape Girardeau Municipal Airport, fly

    1. Drive from Poplar Bluff to Cape Girardeau Municipal Airport (CGI)car car
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Key West International Airport (EYW)plane plane CGI - EYW
    9h 26m
    $234–981

  6. Taxi, bus, bus to Bill And Hillary Clinton National Airport, fly

    1. Take the taxi from Poplar Bluff to Flying J - Matthewstaxi taxi
    2. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Shell Gas Station - Little Rock, ARbus bus
    4. Fly from Bill And Hillary Clinton National Airport (LIT) to Key West International Airport (EYW)plane plane LIT - EYW
    12h 6m
    $408–1,356

  7. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    37h 37m
    $142–337

  8. Train, bus, ferry

    1. Take the train from Poplar Bluff Station to Longviewtrain train
    2. Take the bus from Longview Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    42h 7m
    $399–641

Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW) flights

Calendar38Weekly Planes
Duration6h 5mAverage Duration
Ticket$189Cheapest Price
See schedules

Questions & Answers

What companies run services between Poplar Bluff, MO, USA and Key West, FL, USA?

There is no direct connection from Poplar Bluff to Key West. However, you can take the train to St. Louis, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a vehicle from Poplar Bluff to N Roosevelt & 3rd Street via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 34h 37m.

Airlines
Train operators
Bus operators
Ferry operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Poplar Bluff

Trips to Key West

Popular routes