There are 7 ways to get from Poplar Bluff to Key West by train, plane, car, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Lambert–St. Louis International Airport, fly
best- Take the train from Poplar Bluff Station to St. Louistrain
- Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane STL - EYW
10h 55m$176–623Drive to Cape Girardeau Municipal Airport, fly
cheapest- Drive from Poplar Bluff to Cape Girardeau Municipal Airport (CGI)car
- Fly from Cape Girardeau Municipal Airport (CGI) to Key West International Airport (EYW)plane CGI - EYW
25h 36m$109–431Drive, bus
- Drive from Poplar Bluff to Cape Girardeaucar
- Take the bus from Cape Girardeau to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
34h 52m$216–428Drive 1,231.4 mi
- Drive from Poplar Bluff to Key Westcar 1,231.4 mi
23h 40m$225–325Drive to Mc Kellar-Sipes Regional Airport, fly
- Drive from Poplar Bluff to Mc Kellar-Sipes Regional Airport (MKL)car
- Fly from Mc Kellar-Sipes Regional Airport (MKL) to Key West International Airport (EYW)plane MKL - EYW
6h 58m$111–409Train, bus
- Take the train from Poplar Bluff Station to St. Louistrain
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
38h 47m$258–511Train, bus, ferry
- Take the train from Poplar Bluff Station to Longviewtrain
- Take the bus from Longview Bus Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
42h 7m$512–742
Poplar Bluff to Key West by train, bus, and foot
Questions & Answers
The cheapest way to get from Poplar Bluff to Key West is to drive and fly which costs $110 - $410 and takes 6h 58m.
The fastest way to get from Poplar Bluff to Key West is to drive and fly which takes 6h 58m and costs $110 - $410.
The distance between Poplar Bluff and Key West is 1288 miles. The road distance is 1238.5 miles.
The best way to get from Poplar Bluff to Key West without a car is to train and bus which takes 38h 47m and costs $250 - $550.
It takes approximately 10h 55m to get from Poplar Bluff to Key West, including transfers.
Key West is 1h ahead of Poplar Bluff. It is currently 6:24 AM in Poplar Bluff and 7:24 AM in Key West.
Yes, the driving distance between Poplar Bluff to Key West is 1239 miles. It takes approximately 23h 40m to drive from Poplar Bluff to Key West.
There are 966+ hotels available in Key West.
What companies run services between Poplar Bluff, MO, USA and Key West, FL, USA?
There is no direct connection from Poplar Bluff to Key West. However, you can take the train to St. Louis, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Key West International Airport (EYW), then take the taxi to Key West. Alternatively, you can take a vehicle from Poplar Bluff to N Roosevelt & 3rd Street via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 34h 52m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $130–600
Flights from Lambert–St. Louis International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $120–550
Flights from Cape Girardeau Municipal Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 24h 22m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $110–470
Flights from Cape Girardeau Municipal Airport to Key West International Airport via Pensacola, Miami
- Ave. Duration
- 23h 59m
- When
- Wednesday and Saturday
- Estimated price
- $85–400
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $110–500
Flights from Mc Kellar-Sipes Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 10m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–360
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $130–600
Flights from Cape Girardeau Municipal Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 28h 19m
- When
- Every day
- Estimated price
- $110–470
- Website
- flybreeze.com
Flights from Cape Girardeau Municipal Airport to Key West International Airport via Pensacola, Tampa
- Ave. Duration
- 24h 39m
- When
- Wednesday and Saturday
- Estimated price
- $220–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Poplar Bluff Station to St. Louis
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Amtrak
Train from Poplar Bluff Station to St. Louis
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- Amtrak
Train from Poplar Bluff Station to Longview
- Ave. Duration
- 9h 3m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Cape Girardeau to Memphis Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $27–55
- Website
- Greyhound
Bus from Memphis Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Twice daily
- Estimated price
- $100–200
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- $19–40
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $85–160
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Twice daily
- Estimated price
- $100–200
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Longview Bus Station to Houston Bus Station
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Twice daily
- Estimated price
- $110–180
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $90–150
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Twice daily
- Estimated price
- $110–180
- Schedules at
- Flixbus USA
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Fort Myers
- Ave. Duration
- 20h 38m
- Frequency
- Once daily
- Estimated price
- $170–220
- Schedules at
- Omnibus Express
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide















