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How to get fromPontotoc to St. Louisby plane, bus (Greyhound, Flixbus), car or bus

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There are 6 ways to get from Pontotoc to St. Louis by plane, bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tupelo Regional Airport

    best
    1. Fly from Tupelo Regional Airport (TUP) to Lambert–St. Louis International Airport (STL)planeTUP - STL
    4h 48m
    $154–751

  2. Drive 378.8 mi

    cheapest
    1. Drive from Pontotoc to St. Louiscar378.8 mi
    6h 17m
    $70–100

  3. Bus

    1. Take the bus from Tupelo to Memphis Bus StationbusGreyhound US0610
    2. Take the bus from Memphis Bus Station to St Louis Bus StationbusGreyhound US1173
    8h 30m
    $99–164

  4. Bus to Memphis, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL)planeMEM - STL
    8h 55m
    $348–683

  5. Bus, bus to Jonesboro Municipal Airport, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Take the bus from Memphis Bus Station to Jonesborobus
    3. Fly from Jonesboro Municipal Airport (JBR) to Lambert–St. Louis International Airport (STL)planeJBR - STL
    8h 9m
    $315–856

  6. Bus, bus to Bill And Hillary Clinton National Airport, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus
    2. Take the bus from Tornado Bus Co - West Memphis to Shell Gas Station - Little Rock, ARbus
    3. Fly from Bill And Hillary Clinton National Airport (LIT) to Lambert–St. Louis International Airport (STL)planeLIT - STL
    8h 36m
    $265–1,040

Tupelo Regional Airport (TUP) to Lambert–St. Louis International Airport (STL) flights

Calendar17Weekly Planes
Duration5h 37mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

What companies run services between Pontotoc, MS, USA and St. Louis, MO, USA?

Corporate Flight Management Inc, Southwest Airlines, and American Airlines fly from Tupelo Regional Airport (TUP) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a vehicle from Pontotoc to St Louis Bus Station via Tupelo and Memphis Bus Station in around 8h 30m.

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