Rome2Rio

How to get fromPittsburgh to Wythevilleby bus (Greyhound), train, bus, car, plane or bus (Greyhound, Flixbus)

Find Transport to Wytheville

See all options

There are 7 ways to get from Pittsburgh to Wytheville by bus (Greyhound), train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Cambridge

    best
    1. Take the bus from Pittsburgh Intermodal Station to Cambridge, OHbus
    2. Take the bus from Cambridge to Charleston, WVbus
    3. Take the bus from Charleston, WV to Wythevillebus
    9h 24m
    $79–188

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus
    2. Take the bus from Morgantown to Charlestonbus
    3. Take the bus from Charleston, WV to Wythevillebus
    9h 59m
    $54–163

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Washington Union StationtrainFloridian
    2. Take the bus from Washington Union Station to Rural King Shopping CenterbusVirginia Breeze
    15h 15m
    $115–347

  4. Drive 306.6 mi

    1. Drive from Pittsburgh to Wythevillecar306.6 mi
    5h 21m
    $56–81

  5. Fly to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Pittsburgh International Airport (PIT) to Roanoke Regional Airport-Woodrum Field (ROA)planePIT - ROA
    2. Take the bus from Roanoke Bus Stop to Max Meadowsbus
    9h 9m
    $122–451

  6. Bus via Washington

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union StationbusGreyhound US0164 / ...
    2. Take the bus from Washington Union Station to Rural King Shopping CenterbusVirginia Breeze
    12h 35m
    $84–147

  7. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)planePIT - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus
    7h 59m
    $180–415

Pittsburgh International Airport (PIT) to Roanoke Regional Airport-Woodrum Field (ROA) flights

Calendar88Weekly Planes
Duration4h 44mAverage Duration
Ticket$57Cheapest Price
See schedules

Questions & Answers

What companies run services between Pittsburgh, PA, USA and Wytheville, VA, USA?

You can take a bus from Pittsburgh Intermodal Station to Wytheville via Cambridge, OH, Cambridge, Charleston, WV, and Wytheville in around 9h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Pittsburgh

Trips to Wytheville

Popular routes