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How to get fromPittsburgh to Wiseby plane, car, bus or train

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There are 7 ways to get from Pittsburgh to Wise by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tri-Cities Regional Tn/Va Airport, drive

    best
    1. Fly from Pittsburgh International Airport (PIT) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane PIT - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Wisecar car
    7h 46m
    $101–554

  2. Drive 379.5 mi

    cheapest
    1. Drive from Pittsburgh to Wisecar car 379.5 mi
    7h 4m
    $70–100

  3. Bus, drive via New York

    1. Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus bus
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    20h 48m
    $132–259

  4. Fly to Asheville Regional Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Wisecar car
    9h 7m
    $88–421

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Wisecar car
    8h 1m
    $209–507

  6. Bus, drive

    1. Take the bus from Pittsburgh Intermodal Station to New York City Chinatownbus bus
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    22h 36m
    $133–266

  7. Train, bus, drive

    1. Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    22h 53m
    $166–466

Pittsburgh International Airport (PIT) to Tri-Cities Regional Tn/Va Airport (TRI) flights

Calendar56Weekly Planes
Duration5h 1mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Wise, VA, USA?

There is no direct connection from Pittsburgh to Wise. However, you can take the bus to Pittsburgh International Airport, walk to Pittsburgh-Airport-PIT airport, fly to Tri-Cities Regional Tn/Va Airport (TRI), then drive to Wise. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Wise via Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York City, and Johnson City in around 20h 48m.

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