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There are 8 ways to get from Pittsburgh to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  5h 13m

  1. Fly from Pittsburgh (PIT) to Greenville/Spartanburg (GSP) PIT - GSP

$173 - $398

Cheapest option

Bus  •  18h 3m

  1. Take the bus from Pittsburgh, PA to Washington DC
  2. Take the bus from Washington to Fayetteville, NC
  3. Take the bus from Fayetteville, Nc to Florence, Sc

$74 - $121

6 alternative options

Fly to Columbia  •  6h 38m

  1. Fly from Pittsburgh (PIT) to Columbia (CAE) PIT - CAE

$205 - $1,105

Fly to Charlotte, bus  •  6h 4m

  1. Fly from Pittsburgh (PIT) to Charlotte (CLT) PIT - CLT
  2. Take the bus from Transit Center- Bay X to White Street Park and Ride

$149 - $301

Fly to Myrtle Beach, bus  •  5h 50m

  1. Fly from Pittsburgh (PIT) to Myrtle Beach (MYR) PIT - MYR
  2. Take the bus from Myrtle Beach to Florence, SC

$159 - $617

Train  •  16h 25m

  1. Take the train from Pittsburgh Amtrak Station to Washington Union Station Capitol Limited
  2. Take the train from Washington Union Station to Florence Amtrak Station Palmetto / ...

$117 - $312

Bus via Richmond, Va  •  18h 15m

  1. Take the bus from Pittsburgh, Pa to Baltimore Downtown, Md
  2. Take the bus from Baltimore Downtown, Md to Richmond, Va
  3. Take the bus from Richmond, Va to Fayetteville, Nc
  4. Take the bus from Fayetteville, Nc to Florence, Sc

$91 - $222

Drive  •  9h 56m

  1. Drive from Pittsburgh to Florence 553.6 miles

$50 - $80

Questions & Answers

The cheapest way to get from Pittsburgh to South Carolina is to drive which costs $50 - $80 and takes 9h 56m.

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The quickest way to get from Pittsburgh to South Carolina is to fly which costs $170 - $400 and takes 5h 13m.

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No, there is no direct bus from Pittsburgh to South Carolina. However, there are services departing from Pittsburgh, PA and arriving at Florence, Sc via Washington, 505 Franklin St and Fayetteville, Nc. The journey, including transfers, takes approximately 18h 3m.

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No, there is no direct train from Pittsburgh station to South Carolina station. However, there are services departing from Pittsburgh Amtrak Station and arriving at Florence Amtrak Station via Washington Union Station. The journey, including transfers, takes approximately 16h 25m.

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The distance between Pittsburgh and South Carolina is 470 miles. The road distance is 553.6 miles.

Get driving directions

The best way to get from Pittsburgh to South Carolina without a car is to train which takes 16h 25m and costs $110 - $320.

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It takes approximately 5h 13m to get from Pittsburgh to South Carolina, including transfers.

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Pittsburgh to South Carolina bus services, operated by Greyhound USA, depart from Pittsburgh, Pa station.

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Pittsburgh to South Carolina train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.

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The best way to get from Pittsburgh to South Carolina is to fly which takes 5h 13m and costs $170 - $400. Alternatively, you can train, which costs $110 - $320 and takes 16h 25m, you could also bus, which costs $70 - $130 and takes 18h 3m.

Mode details

Map of how to get from Pittsburgh to South Carolina.
Launch map view
  • Distance: 470 miles
  • Duration: 5h 13m

What companies run services between Pittsburgh, PA, USA and South Carolina, USA?

American Airlines, United Airlines and two other airlines fly from Pittsburgh to Greenville hourly. Alternatively, you can take a train from Pittsburgh to Florence via Washington Union Station in around 16h 25m.

Airlines
American Airlines
Website
aa.com
Flights from Pittsburgh to Greenville/Spartanburg via Charlotte
Ave. Duration
3h 46m
When
Every day
Estimated price
$200 - $370
Flights from Pittsburgh to Greenville/Spartanburg via Reagan Washington
Ave. Duration
4h 11m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $370
Flights from Pittsburgh to Greenville/Spartanburg via Philadelphia
Ave. Duration
4h 8m
When
Every day
Estimated price
$200 - $370
Flights from Pittsburgh to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4h 30m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $370
Flights from Pittsburgh to Columbia via Charlotte
Ave. Duration
4h 10m
When
Every day
Estimated price
$200 - $1,100
Flights from Pittsburgh to Columbia via Philadelphia
Ave. Duration
5h 23m
When
Every day
Estimated price
$240 - $1,100
Flights from Pittsburgh to Columbia via Reagan Washington
Ave. Duration
4h 42m
When
Monday to Friday
Estimated price
$220 - $1,100
Flights from Pittsburgh to Columbia via New York La Guardia
Ave. Duration
6h 15m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
Flights from Pittsburgh to Columbia via Dallas/Ft.Worth
Ave. Duration
6h 44m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,400
Flights from Pittsburgh to Charlotte
Ave. Duration
1h 42m
When
Every day
Estimated price
$290 - $650
Flights from Pittsburgh to Myrtle Beach via Charlotte
Ave. Duration
3h 47m
When
Every day
Estimated price
$290 - $1,200
Delta
Website
delta.com
Flights from Pittsburgh to Greenville/Spartanburg via Atlanta
Ave. Duration
4h 12m
When
Every day
Estimated price
$200 - $850
Flights from Pittsburgh to Greenville/Spartanburg via Detroit
Ave. Duration
4h 32m
When
Saturday and Sunday
Estimated price
$200 - $850
Flights from Pittsburgh to Columbia via Atlanta
Ave. Duration
4h 27m
When
Every day
Estimated price
$210 - $1,100
Flights from Pittsburgh to Columbia via New York La Guardia
Ave. Duration
6h 1m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,200
United Airlines
Website
united.com
Flights from Pittsburgh to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3h 56m
When
Every day
Estimated price
$200 - $700
Flights from Pittsburgh to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4h 35m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $700
Flights from Pittsburgh to Columbia via Washington Dulles
Ave. Duration
4h
When
Every day
Estimated price
$230 - $1,100
Flights from Pittsburgh to Columbia via Chicago O'Hare
Ave. Duration
5h 24m
When
Every day
Estimated price
$270 - $1,300
Flights from Pittsburgh to Charlotte via Washington Dulles
Ave. Duration
3h 35m
When
Every day
Estimated price
$210 - $600
Southwest Airlines
Website
southwest.com
Flights from Pittsburgh to Greenville/Spartanburg via Atlanta
Ave. Duration
4h 15m
When
Monday to Friday
Estimated price
$260 - $950
Flights from Pittsburgh to Charlotte via Baltimore
Ave. Duration
3h 30m
When
Monday to Friday
Estimated price
$280 - $650
Allegiant Air
Website
allegiantair.com
Flights from Pittsburgh to Myrtle Beach
Ave. Duration
1h 27m
When
Monday and Friday
Estimated price
$80 - $490
Spirit Airlines
Website
spirit.com
Flights from Pittsburgh to Myrtle Beach
Ave. Duration
1h 32m
When
Tuesday, Thursday and Sunday
Estimated price
$140 - $650
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Pittsburgh Amtrak Station to Washington Union Station
Ave. Duration
7h 45m
Frequency
Once daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Train from Washington Union Station to Florence Amtrak Station
Ave. Duration
7h 40m
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1h 12m
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Myrtle Beach to Florence, SC
Ave. Duration
1h 30m
Frequency
Once daily
Estimated price
$18 - $29
Schedules at
southeasternstages.com
Bus from Fayetteville, NC to Florence, SC
Ave. Duration
1h 30m
Frequency
4 times a day
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Pittsburgh, PA to Washington DC
Ave. Duration
6h 25m
Frequency
Once daily
Estimated price
$27 - $40
Book at
megabus.com
Bus from Washington to Fayetteville, NC
Ave. Duration
7h 55m
Frequency
Twice daily
Estimated price
$30 - $45
Book at
megabus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1h 35m
Frequency
5 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35
Bus from Pittsburgh, Pa to Baltimore Downtown, Md
Ave. Duration
6h
Frequency
3 times a day
Estimated price
$30 - $80
Website
greyhound.com
Economy
$30 - $50
Flexible
$60 - $80
Bus from Baltimore Downtown, Md to Richmond, Va
Ave. Duration
3h 20m
Frequency
Every 4 hours
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Richmond, Va to Fayetteville, Nc
Ave. Duration
4h 20m
Frequency
Every 2 hours
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65

Want to know more about travelling around United States

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More Questions & Answers

There is no direct flight from Pittsburgh Airport to Greenville/Spartanburg Airport. The quickest flight takes 3h 17m and has one stopover.

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Pittsburgh to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

More details

Pittsburgh to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak Station.

More details

Yes, the driving distance between Pittsburgh to South Carolina is 554 miles. It takes approximately 9h 56m to drive from Pittsburgh to South Carolina.

Get driving directions

Southwest Airlines, United Airlines, Delta and American Airlines offer flights from Pittsburgh Airport to Greenville/Spartanburg Airport.

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Book your Pittsburgh to South Carolina train tickets online with Rome2rio.

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Book your Pittsburgh to South Carolina bus tickets online with Greyhound, Greyhound and two other operators.

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There are 18+ hotels available in South Carolina. Prices start at $49 USD per night.

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The best way to get from Pittsburgh to Pittsburgh Airport is to bus which takes 39m and costs $3.

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