There are 6 ways to get from Pittsburgh to Simpsonville by bus, plane, bus (Greyhound), train, taxi, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Greenville–Spartanburg International Airport
best- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane PIT - GSP
4h 5mFly to Asheville Regional Airport, drive
cheapest- Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane PIT - AVL
- Drive from Asheville-Airport-AVL to Simpsonvillecar
7h 29m$76–413Bus via Charleston
- Take the bus from Pittsburgh Greyhound to Westover Terminalbus
- Take the bus from Morgantown to Charlestonbus
- Take the bus from Charleston, WV to Charlotte Bus Stationbus
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
17h 20m$152–369Train, bus, taxi
- Take the train from Pittsburgh Amtrak Station to Carytrain
- Take the train from Cary to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte to Servicios Zapata - Spartanburgbus
- Take the taxi from Servicios Zapata - Spartanburg to Simpsonvilletaxi
22h 29m$321–669Drive 524.5 mi
- Drive from Pittsburgh to Simpsonvillecar 524.5 mi
9h 35m$96–139Bus
- Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Gastonia Transitbus
- Take the bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenvillebus
20h 22m$169–411
Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Pittsburgh to Simpsonville is to drive which costs $95 - $140 and takes 9h 35m.
The fastest way to get from Pittsburgh to Simpsonville is to fly and drive which takes 7h 29m and costs $75 - $420.
The distance between Pittsburgh and Simpsonville is 442 miles. The road distance is 527.6 miles.
The best way to get from Pittsburgh to Simpsonville without a car is to bus via Charleston which takes 17h 20m and costs $150 - $370.
It takes approximately 4h 5m to get from Pittsburgh to Simpsonville, including transfers.
Yes, the driving distance between Pittsburgh to Simpsonville is 528 miles. It takes approximately 9h 35m to drive from Pittsburgh to Simpsonville.
There are 220+ hotels available in Simpsonville.
What companies run services between Pittsburgh, PA, USA and Simpsonville, SC, USA?
You can take a bus from Pittsburgh Greyhound to N Maple St & W Curtis St via Westover Terminal, Morgantown, Charleston, WV, Charlotte Bus Station, Charlotte, Taqueria Guadalajara - Greenville, and 510 & 601 Connection in around 17h 20m.
- Website
- aa.com
Flights from Pittsburgh International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $90–600
Flights from Pittsburgh International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $65–400
Flights from Pittsburgh International Airport to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $85–480
- Website
- delta.com
Flights from Pittsburgh International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $80–460
- Website
- united.com
Flights from Pittsburgh International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Pittsburgh International Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $110–650
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 27m
- When
- Thursday and Sunday
- Estimated price
- $180–1,500
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Cary
- Ave. Duration
- 14h 41m
- Frequency
- Once daily
- Estimated price
- $160–350
- Website
- https://www.amtrak.com/home.html
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $40–95
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Website
- https://www.rideprt.org
- Phone
- +1 304-291-7433
- Website
- busride.org
Bus from Pittsburgh Greyhound to Westover Terminal
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $3–30
- Website
- https://www.busride.org
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Morgantown to Charleston
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $15–55
- Website
- https://baronsbus.com
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $26–70
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Charleston, WV to Charlotte Bus Station
- Ave. Duration
- 6h 35m
- Frequency
- Once daily
- Estimated price
- $45–85
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to Washington Union Station
- Ave. Duration
- 5h 5m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- Every 4 hours
- Estimated price
- $45–85
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Gastonia Transit
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Charlotte to Servicios Zapata - Spartanburg
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–130
Bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenville
- Ave. Duration
- 1h 57m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Pittsburgh Intermodal Station to Washington Union Station
- Ave. Duration
- 4h 45m
- Frequency
- 4 times a week
- Estimated price
- $29–55
- Schedules at
- flixbus.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- 3 times a day
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide












