There are 8 ways to get from Pittsburgh to Natick by bus, plane, train, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Pittsburgh International Airport, fly to Boston Logan Airport, train
best- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Boston Logan Airport (BOS)plane PIT - BOS
- Take the train from Back Bay to Natick Centertrain
5h 46mBus
cheapest- Take the bus from Pittsburgh Greyhound to Port Authority Bus Terminalbus Pittsburgh
- Take the bus from New York to Bostonbus Ppb 5623 / ...
14h 40m$92–160Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain Pennsylvanian
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain Acela
15h$365–580Drive 552 mi
- Drive from Pittsburgh to Natickcar 552 mi
10h 6m$101–146Bus to Pittsburgh International Airport, fly to Theodore Francis Green State Airport, train
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Theodore Francis Green State Airport (PVD)plane PIT - PVD
- Take the train from TF Green Airport to Back Baytrain
- Take the train from Back Bay to Natick Centertrain
7h 42mTrain to Cleveland-Hopkins International Airport, fly to Boston Logan Airport
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Boston Logan Airport (BOS)plane CLE - BOS
8h 28m$221–1,088Fly Pittsburgh International Airport to Manchester Airport, bus
- Fly from Pittsburgh International Airport (PIT) to Manchester Airport (MHT)plane PIT - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
9h 56m$93–477Bus, train
- Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Worcester Union Stationbus
- Take the train from Worcester to Natick Centertrain
16h$114–176
Pittsburgh to Natick by bus
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Natick is to bus which costs $90 - $160 and takes 14h 40m.
The fastest way to get from Pittsburgh to Natick is to train and fly which takes 8h 28m and costs $220 - $1,100.
No, there is no direct bus from Pittsburgh to Natick. However, there are services departing from Pittsburgh Greyhound and arriving at Natick Center - South Ave opp Adams St via New York and South Station - Bus Terminal Gates 4-6. The journey, including transfers, takes approximately 14h 40m.
No, there is no direct train from Pittsburgh station to Natick. However, there are services departing from Pittsburgh Amtrak Station and arriving at Natick Center via Ny Moynihan Train Hall At Penn Station and Back Bay. The journey, including transfers, takes approximately 15h.
The distance between Pittsburgh and Natick is 551 miles. The road distance is 555.2 miles.
The best way to get from Pittsburgh to Natick without a car is to bus which takes 14h 40m and costs $90 - $160.
It takes approximately 5h 46m to get from Pittsburgh to Natick, including transfers.
Pittsburgh to Natick bus services, operated by Megabus, depart from Pittsburgh Greyhound station.
Pittsburgh to Natick train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Natick is to bus which takes 14h 40m and costs $90 - $160. Alternatively, you can train, which costs $360 - $600 and takes 15h.
What companies run services between Pittsburgh, PA, USA and Natick, MA, USA?
You can take a bus from Pittsburgh Greyhound to Natick Center - South Ave opp Adams St via Port Authority Bus Terminal, New York, Boston, and South Station - Bus Terminal Gates 4-6 in around 14h 40m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Natick Center via Ny Moynihan Train Hall At Penn Station, Boston, and Back Bay in around 15h.
- Website
- united.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–480
Flights from Pittsburgh International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 3h 52m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $85–500
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $60–350
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 53m
- When
- Sunday
- Estimated price
- $85–490
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 4h 4m
- When
- Monday, Thursday, Sunday, Tuesday, Wednesday, and Friday
- Estimated price
- $95–550
Flights from Pittsburgh International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $80–470
- Website
- southwest.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 52m
- When
- Sunday
- Estimated price
- $85–490
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $60–350
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $95–550
Flights from Pittsburgh International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $80–470
Flights from Pittsburgh International Airport to Manchester Airport via Chicago Midway
- Ave. Duration
- 7h 2m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $130–650
- Website
- aa.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $85–490
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 3h 47m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $55–350
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 3h 51m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–360
Flights from Pittsburgh International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $80–460
Flights from Pittsburgh International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $80–470
Flights from Pittsburgh International Airport to Manchester Airport via Charlotte
- Ave. Duration
- 5h 17m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
- Website
- delta.com
Flights from Pittsburgh International Airport to Boston Logan Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $80–470
Flights from Pittsburgh International Airport to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $80–480
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $85–480
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Detroit
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $95–550
- Website
- jetblue.com
Flights from Pittsburgh International Airport to Boston Logan Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $80–470
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $85–480
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 1h 32m
- When
- Thursday and Sunday
- Estimated price
- $120–850
Train from Back Bay to Natick Center
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from TF Green Airport to Back Bay
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from Back Bay to Natick Center
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from Worcester to Natick Center
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $240–380
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
- Phone
- +1-877-462-6342
- questions@us.megabus.com
- Website
- Megabus
Bus from Pittsburgh Greyhound to Port Authority Bus Terminal
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Port Authority Bus Terminal
- Ave. Duration
- 8h 50m
- Frequency
- Every 4 hours
- Estimated price
- $75–120
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Worcester Union Station
- Ave. Duration
- 4h 20m
- Frequency
- 4 times a day
- Estimated price
- $30–50
- Website
- Greyhound
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Booking & Getting There
Pittsburgh to Natick bus services, operated by Megabus, arrive at Port Authority Bus Terminal station.
Pittsburgh to Natick train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Pittsburgh to Natick is 555 miles. It takes approximately 10h 6m to drive from Pittsburgh to Natick.
There are 474+ hotels available in Natick.


















