There are 4 ways to get from Pittsburgh to Manlius by train (Amtrak), bus (Flixbus, Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Pittsburgh Amtrak Station to Cleveland AmtrakFloridian
- Take the train from Cleveland Amtrak to Syracuse Regional Transportation CenterLake Shore Limited
9h 55m$149–311Drive 327.1 mi
cheapest- Drive from Pittsburgh to Manlius327.1 mi
7h 56m$60–87Bus
- Take the bus from Pittsburgh to BuffaloFab510
- Take the bus from Buffalo to Syracuse Bus StationFlixBus 2685 / ...
14h 30m$73–235Fly
- Fly from Pittsburgh International Airport (PIT) to Syracuse Hancock International Airport (SYR)PIT - SYR
6h 3m$402–785
Pittsburgh to Manlius by bus
Questions & Answers
The cheapest way to get from Pittsburgh to Manlius is to drive which costs $55 - $90 and takes 7h 56m.
The fastest way to get from Pittsburgh to Manlius is to fly which takes 6h 3m and costs $400 - $800.
No, there is no direct bus from Pittsburgh to Manlius. However, there are services departing from Pittsburgh and arriving at Fayette St & W Seneca St via Buffalo, Regional Transportation Center and A2. The journey, including transfers, takes approximately 14h 30m.
The distance between Pittsburgh and Manlius is 479 miles. The road distance is 329 miles.
The best way to get from Pittsburgh to Manlius without a car is to train which takes 9h 55m and costs $140 - $320.
It takes approximately 9h 55m to get from Pittsburgh to Manlius, including transfers.
Pittsburgh to Manlius bus services, operated by Fullington Trailways, depart from Pittsburgh station.
The best way to get from Pittsburgh to Manlius is to train which takes 9h 55m and costs $140 - $320. Alternatively, you can bus, which costs $70 - $240 and takes 14h 30m, you could also fly, which costs $400 - $800 and takes 6h 3m.
Pittsburgh to Manlius bus services, operated by Fullington Trailways, arrive at Buffalo station.
Yes, the driving distance between Pittsburgh to Manlius is 329 miles. It takes approximately 7h 56m to drive from Pittsburgh to Manlius.
What companies run services between Pittsburgh, PA, USA and Manlius, NY, USA?
You can take a train from Pittsburgh Amtrak Station to Manlius via Cleveland Amtrak and Syracuse Regional Transportation Center in around 9h 55m. Alternatively, you can take a bus from Pittsburgh to Fayette St & W Seneca St via Buffalo, Regional Transportation Center, B14, and A2 in around 14h 30m.
- Website
- delta.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $120–700
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 5h 44m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via New York JFK
- Ave. Duration
- 6h 59m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
- Website
- united.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $110–700
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Newark
- Ave. Duration
- 5h 31m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
- Website
- aa.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $110–700
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 5h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://www.amtrak.com/home.html
Train from Cleveland Amtrak to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 38m
- Frequency
- Twice daily
- Estimated price
- $45–150
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $110–150
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $28–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 93+ hotels available in Manlius.