There are 4 ways to get from Pittsburgh to Manlius by train (Amtrak), bus (Flixbus, Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain Floridian
- Take the train from Cleveland Amtrak to Syracuse Regional Transportation Centertrain Lake Shore Limited
9h 52m$137–319Drive 327.1 mi
cheapest- Drive from Pittsburgh to Manliuscar 327.1 mi
7h 58m$60–87Bus
- Take the bus from Pittsburgh to Buffalobus Fab510
- Take the bus from Buffalo to Syracuse Bus Stationbus FlixBus 2686 / ...
13h 52m$73–235Fly
- Fly from Pittsburgh International Airport (PIT) to Syracuse Hancock International Airport (SYR)plane PIT - SYR
6h 15m$411–785
Pittsburgh to Manlius by bus
Questions & Answers
The cheapest way to get from Pittsburgh to Manlius is to drive which costs $55 - $90 and takes 7h 58m.
The fastest way to get from Pittsburgh to Manlius is to fly which takes 6h 15m and costs $410 - $800.
No, there is no direct bus from Pittsburgh to Manlius. However, there are services departing from Pittsburgh and arriving at Fayette St & W Seneca St via Buffalo, Regional Transportation Center and A2. The journey, including transfers, takes approximately 13h 52m.
The distance between Pittsburgh and Manlius is 480 miles. The road distance is 329 miles.
The best way to get from Pittsburgh to Manlius without a car is to train which takes 9h 52m and costs $130 - $320.
It takes approximately 9h 52m to get from Pittsburgh to Manlius, including transfers.
Pittsburgh to Manlius bus services, operated by Fullington Trailways, depart from Pittsburgh station.
The best way to get from Pittsburgh to Manlius is to train which takes 9h 52m and costs $130 - $320. Alternatively, you can bus, which costs $70 - $240 and takes 13h 52m, you could also fly, which costs $410 - $800 and takes 6h 15m.
Pittsburgh to Manlius bus services, operated by Fullington Trailways, arrive at Buffalo station.
Yes, the driving distance between Pittsburgh to Manlius is 329 miles. It takes approximately 7h 58m to drive from Pittsburgh to Manlius.
What companies run services between Pittsburgh, PA, USA and Manlius, NY, USA?
You can take a train from Pittsburgh Amtrak Station to Manlius via Cleveland Amtrak and Syracuse Regional Transportation Center in around 9h 52m. Alternatively, you can take a bus from Pittsburgh to Fayette St & W Seneca St via Buffalo, Regional Transportation Center, B14, and A2 in around 13h 52m.
- Website
- delta.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $120–750
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via New York JFK
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $120–750
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $130–800
- Website
- aa.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $120–750
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $120–750
- Website
- united.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Newark
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $120–750
- Website
- jetblue.com
Flights from Pittsburgh International Airport to Syracuse Hancock International Airport via Boston
- Ave. Duration
- 4h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $27–75
- Website
- https://www.amtrak.com/home.html
Train from Cleveland Amtrak to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 38m
- Frequency
- Twice daily
- Estimated price
- $35–150
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $110–150
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- $29–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $30–45
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 93+ hotels available in Manlius.








