There are 7 ways to get from Pittsburgh to Lowell by bus, plane, train, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Pittsburgh International Airport, fly to Boston Logan Airport, train
best- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Boston Logan Airport (BOS)plane PIT - BOS
- Take the train from Anderson/Woburn to Lowelltrain
5h 44mFly Pittsburgh International Airport to Theodore Francis Green State Airport, train
cheapest- Fly from Pittsburgh International Airport (PIT) to Theodore Francis Green State Airport (PVD)plane PIT - PVD
- Take the train from TF Green Airport to Rugglestrain
- Take the train from North Station to Lowelltrain
7h 55m$77–386Bus via Boston
- Take the bus from Pittsburgh Greyhound to Port Authority Bus Terminalbus
- Take the bus from New York to Bostonbus
- Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus
14h 42m$95–162Train
- Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the train from North Station to Lowelltrain
15h 14m$187–478Drive 570.1 mi
- Drive from Pittsburgh to Lowellcar 570.1 mi
10h 25m$104–151Train to Cleveland-Hopkins International Airport, fly to Boston Logan Airport
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Boston Logan Airport (BOS)plane CLE - BOS
8h 33m$182–1,066Bus (Greyhound)
- Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus Greyhound US0421 / ...
- Take the bus from Port Authority Bus Terminal to Robert B Kennedy Bus Transfer Centerbus Greyhound US0256S
18h 5m$112–181
Pittsburgh to Lowell by bus
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Lowell is to bus via Boston which costs $95 - $170 and takes 14h 42m.
The fastest way to get from Pittsburgh to Lowell is to fly and train which takes 7h 55m and costs $75 - $390.
No, there is no direct bus from Pittsburgh to Lowell. However, there are services departing from Pittsburgh Greyhound and arriving at Robert B Kennedy Bus Transfer Center via New York and Boston. The journey, including transfers, takes approximately 14h 42m.
No, there is no direct train from Pittsburgh station to Lowell. However, there are services departing from Pittsburgh Amtrak Station and arriving at Lowell via Ny Moynihan Train Hall At Penn Station, Back Bay and North Station. The journey, including transfers, takes approximately 15h 14m.
The distance between Pittsburgh and Lowell is 552 miles. The road distance is 573.4 miles.
The best way to get from Pittsburgh to Lowell without a car is to bus via Boston which takes 14h 42m and costs $95 - $170.
It takes approximately 5h 44m to get from Pittsburgh to Lowell, including transfers.
Pittsburgh to Lowell bus services, operated by Megabus, depart from Pittsburgh Greyhound station.
Pittsburgh to Lowell train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Lowell is to bus via Boston which takes 14h 42m and costs $95 - $170. Alternatively, you can train, which costs $180 - $480 and takes 15h 14m.
What companies run services between Pittsburgh, PA, USA and Lowell, MA, USA?
You can take a bus from Pittsburgh Greyhound to Robert B Kennedy Bus Transfer Center via Port Authority Bus Terminal, New York, and Boston in around 14h 42m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Lowell via Ny Moynihan Train Hall At Penn Station, Boston, Back Bay, North Station, and North Station in around 15h 14m.
- Website
- united.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $75–460
Flights from Pittsburgh International Airport to Boston Logan Airport via Toronto
- Ave. Duration
- 3h 55m
- When
- Saturday and Sunday
- Estimated price
- $90–500
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $60–370
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $95–550
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 4h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–490
- Website
- delta.com
Flights from Pittsburgh International Airport to Boston Logan Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $75–460
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $80–480
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Detroit
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $95–550
- Website
- jetblue.com
Flights from Pittsburgh International Airport to Boston Logan Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $75–460
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $80–480
- Website
- southwest.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 53m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $80–480
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $60–370
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $90–550
- Website
- aa.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $80–470
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 3h 47m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–360
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–370
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $90–500
- Website
- aircanada.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Toronto
- Ave. Duration
- 3h 55m
- When
- Saturday and Sunday
- Estimated price
- $90–500
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 1h 32m
- When
- Thursday and Sunday
- Estimated price
- $130–850
Train from Anderson/Woburn to Lowell
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from TF Green Airport to Ruggles
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $120–310
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $60–160
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $35–100
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
- Phone
- +1-877-462-6342
- questions@us.megabus.com
- Website
- Megabus
Bus from Pittsburgh Greyhound to Port Authority Bus Terminal
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–7
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Port Authority Bus Terminal
- Ave. Duration
- 8h 50m
- Frequency
- Every 4 hours
- Estimated price
- $70–120
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 8h 15m
- Frequency
- 5 times a week
- Estimated price
- $40–70
- Website
- Greyhound
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Booking & Getting There
Pittsburgh to Lowell bus services, operated by Megabus, arrive at Port Authority Bus Terminal station.
Pittsburgh to Lowell train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Pittsburgh to Lowell is 573 miles. It takes approximately 10h 25m to drive from Pittsburgh to Lowell.
Book your Pittsburgh to Lowell bus tickets online with Omio.
There are 116+ hotels available in Lowell.


















