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How to get fromPittsburgh to Lexingtonby bus (Greyhound), car, plane or bus (Flixbus, Greyhound)

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There are 6 ways to get from Pittsburgh to Lexington by bus (Greyhound), car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Columbus

    best
    1. Take the bus from Pittsburgh Intermodal Station to Columbus Bus Stationbus bus
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OHbus bus
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    8h 52m
    $94–215

  2. Drive 346.6 mi

    cheapest
    1. Drive from Pittsburgh to Lexingtoncar car 346.6 mi
    7h 26m
    $64–92

  3. Fly to Louisville International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 51m
    $202–429

  4. Bus (Greyhound)

    1. Take the bus from Pittsburgh Intermodal Station to Dayton Trotwood Bus Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus Greyhound US0110
    10h 37m
    $107–195

  5. Bus #2

    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    2. Take the bus from Columbus to Dayton Trotwood Bus Stationbus bus
    3. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus
    11h 37m
    $86–218

  6. Fly to Blue Grass Airport

    1. Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane plane PIT - LEX
    8h 42m
    $69–383

Pittsburgh International Airport (PIT) to Louisville International Airport (SDF) flights

Calendar23Weekly Planes
Duration5h 33mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Lexington, KY, USA?

You can take a bus from Pittsburgh Intermodal Station to Lexington via N Wilson Rd & Ferrell Pl - Columbus, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 8h 52m. Alternatively, American Airlines, Delta, and United Airlines fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX) hourly.

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Need to know: Greyhound

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