There are 8 ways to get from Pittsburgh to Key Largo by plane, shuttle, bus (Greyhound, Flixbus), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pittsburgh International Airport to Miami International Airport, shuttle
best- Fly from Pittsburgh International Airport (PIT) to Miami International Airport (MIA)plane PIT - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 12m$679–1,057Fly Pittsburgh International Airport to Key West International Airport, bus
cheapest- Fly from Pittsburgh International Airport (PIT) to Key West International Airport (EYW)plane PIT - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
8h 45m$114–490Bus
- Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
29h 50m$204–323Train, bus
- Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain Floridian
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus 301
40h 31m$415–902Drive 1,227.2 mi
- Drive from Pittsburgh to Key Largocar 1,227.2 mi
20h 44m$224–324Fly Pittsburgh International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Pittsburgh International Airport (PIT) to Fort Lauderdale–Hollywood International Airport (FLL)plane PIT - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 32m$245–752Train to Cleveland-Hopkins International Airport, fly to Miami International Airport, shuttle
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Miami International Airport (MIA)plane CLE - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
9h 59m$259–1,011Fly Pittsburgh International Airport to President Donald J. Trump International Airport, train, bus
- Fly from Pittsburgh International Airport (PIT) to President Donald J. Trump International Airport (PBI)plane PIT - PBI
- Take the train from West Palm Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
10h 31m$134–606
Pittsburgh to Key Largo by bus
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Key Largo is to bus which costs $200 - $330 and takes 29h 50m.
The fastest way to get from Pittsburgh to Key Largo is to fly and shuttle which takes 7h 12m and costs $650 - $1,100.
No, there is no direct bus from Pittsburgh station to Key Largo. However, there are services departing from Pittsburgh Intermodal Station and arriving at Key Largo Bus Stop via Washington Union Station and Miami Airport Station. The journey, including transfers, takes approximately 29h 50m.
The distance between Pittsburgh and Key Largo is 1105 miles. The road distance is 1234.4 miles.
The best way to get from Pittsburgh to Key Largo without a car is to bus which takes 29h 50m and costs $200 - $330.
It takes approximately 7h 12m to get from Pittsburgh to Key Largo, including transfers.
Pittsburgh to Key Largo bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Key Largo bus services, operated by Greyhound USA, arrive at Washington Union Station.
Yes, the driving distance between Pittsburgh to Key Largo is 1234 miles. It takes approximately 20h 44m to drive from Pittsburgh to Key Largo.
Book your Pittsburgh to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Pittsburgh, PA, USA and Key Largo, FL, USA?
You can take a bus from Pittsburgh Intermodal Station to Key Largo Bus Stop via Washington Union Station and Miami Airport Station in around 29h 50m.
- Website
- southwest.com
Flights from Pittsburgh International Airport to Miami International Airport via Orlando
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $120–600
Flights from Pittsburgh International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $120–600
Flights from Pittsburgh International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $120–650
Flights from Pittsburgh International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 4h 40m
- When
- Saturday and Sunday
- Estimated price
- $130–650
Flights from Cleveland-Hopkins International Airport to Miami International Airport via Nashville
- Ave. Duration
- 4h 52m
- When
- Saturday and Sunday
- Estimated price
- $140–700
Flights from Pittsburgh International Airport to President Donald J. Trump International Airport via Orlando
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $120–600
Flights from Pittsburgh International Airport to President Donald J. Trump International Airport via Baltimore
- Ave. Duration
- 4h 41m
- When
- Saturday, Tuesday, Wednesday, and Sunday
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 36h 44m
- Frequency
- Once daily
- Estimated price
- $400–900
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Want to know more about travelling around United States
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Booking & Getting There
There are 343+ hotels available in Key Largo.




