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How to get fromPittsburgh to Iowaby plane, train, bus, bus (Greyhound), car, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Pittsburgh to Iowa by plane, train, bus, bus (Greyhound), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Pittsburgh International Airport (PIT) to Des Moines (DSM)plane plane PIT - DSM
    5h 53m
    $165–772

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Quad City International Airport (MLI)plane plane PIT - MLI
    7h 46m
    $81–431

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    17h 30m
    $214–411

  4. Bus (Greyhound)

    1. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    18h 45m
    $134–243

  5. Drive 775.6 mi

    1. Drive from Pittsburgh to Des Moinescar car 775.6 mi
    12h 50m
    $142–205

  6. Fly to Omaha

    1. Fly from Pittsburgh International Airport (PIT) to Omaha (OMA)plane plane PIT - OMA
    6h 13m
    $157–669

  7. Fly to The Eastern Iowa Airport

    1. Fly from Pittsburgh International Airport (PIT) to The Eastern Iowa Airport (CID)plane plane PIT - CID
    6h 32m
    $124–494

  8. Train, bus via Galesburg

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    19h 22m
    $244–486

  9. Bus via Chicago

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    20h 1m
    $143–241

Pittsburgh International Airport (PIT) to Des Moines (DSM) flights

Calendar149Weekly Planes
Duration5h 24mAverage Duration
Ticket$148Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Iowa.ExpandLaunch map view
  • Distance: 733 mi
  • Duration: 5h 53m

What companies run services between Pittsburgh, PA, USA and Iowa, USA?

Southwest Airlines, Delta, and two other airlines fly from Pittsburgh International Airport (PIT) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Des Moines via Indianapolis Union Station and Des Moines in around 18h 45m.

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