There are 7 ways to get from Pittsburgh to Great Smoky Mountains National Park by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, drive  •  6 h 44 min

  1. Fly from Pittsburgh (PIT) to Knoxville (TYS) PIT - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$208 - $1,012

Cheapest option

Bus, drive  •  20 h 2 min

  1. Take the bus from Pittsburgh, Pa to Columbus, Oh
  2. Take the bus from Columbus, Oh to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains National Park

$90 - $225

5 alternative options

Fly to Asheville, drive  •  6 h 38 min

  1. Fly from Pittsburgh (PIT) to Asheville (AVL) PIT - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$200 - $564

Train, bus, drive via Greensboro Galyon Transportation Center Amtrak  •  21 h 13 min

  1. Take the train from Pittsburgh Amtrak to Washington Union Station Amtrak
  2. Take the train from Washington Union Station Amtrak to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Asheville, Nc
  5. Drive from Asheville, Nc to Great Smoky Mountains National Park

$138 - $343

Train, bus NYTN Bus, drive  •  24 h 1 min

  1. Take the train from Pittsburgh Amtrak to New York Penn Station
  2. Take the bus from New York, NY to Knoxville, TN
  3. Drive from Knoxville, TN to Great Smoky Mountains National Park

$179 - $397

Bus, drive via Washington, Dc  •  24 h 12 min

  1. Take the bus from Pittsburgh, Pa to Washington, Dc
  2. Take the bus from Washington, Dc to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains National Park

$103 - $246

Drive  •  8 h 33 min

  1. Drive from Pittsburgh to Great Smoky Mountains National Park 519.2 miles

$50 - $75

Questions & Answers

The cheapest way to get from Pittsburgh to Great Smoky Mountains National Park is to drive which costs $50 - $75 and takes 8 h 33 min.

More details

The quickest way to get from Pittsburgh to Great Smoky Mountains National Park is to fly and drive which costs $200 - $600 and takes 6 h 38 min.

More details

The distance between Pittsburgh and Great Smoky Mountains National Park is 387 miles. The road distance is 519.2 miles.

Get driving directions

It takes approximately 6 h 44 min to get from Pittsburgh to Great Smoky Mountains National Park, including transfers.

More details

The best way to get from Pittsburgh to Great Smoky Mountains National Park without a car is to bus and drive which takes 20 h 2 min and costs $90 - $230.

More details

Map of how to get from Pittsburgh to Great Smoky Mountains National Park.
Launch map view
  • Distance: 387.4 miles
  • Duration: 6 h 44 min

What companies run services between Pittsburgh, PA, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Pittsburgh to Great Smoky Mountains National Park. However, you can take the bus to Pgh Internl Airport Lower Level, take the walk to Pittsburgh airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the bus to Pgh Internl Airport Lower Level, take the walk to Pittsburgh airport, fly to Asheville, then take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Pittsburgh to Knoxville via Atlanta
Ave. Duration
3 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $1,000
Flights from Pittsburgh to Knoxville via Detroit
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$200 - $1,000
Flights from Pittsburgh to Asheville via Atlanta
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$340 - $1,100
American Airlines
Website
aa.com
Flights from Pittsburgh to Knoxville via Charlotte
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$200 - $1,000
Flights from Pittsburgh to Knoxville via Philadelphia
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from Pittsburgh to Asheville via Charlotte
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$310 - $1,100
United Airlines
Website
united.com
Flights from Pittsburgh to Knoxville via Washington Dulles
Ave. Duration
3 h 51 min
When
Every day
Estimated price
$220 - $1,100
Flights from Pittsburgh to Knoxville via Chicago O'Hare
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$240 - $1,200
Flights from Pittsburgh to Asheville via Newark
Ave. Duration
5 h 11 min
When
Tuesday and Saturday
Estimated price
$340 - $1,100
Flights from Pittsburgh to Asheville via Chicago O'Hare
Ave. Duration
5 h 25 min
When
Every day
Estimated price
$340 - $1,100
Allegiant Air
Website
allegiantair.com
Flights from Pittsburgh to Asheville via St. Petersburg
Ave. Duration
6 h 15 min
When
Monday, Friday and Saturday
Estimated price
$220 - $1,100
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Pittsburgh Amtrak to Washington Union Station Amtrak
Ave. Duration
7 h 45 min
Frequency
Once daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Train from Washington Union Station Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
5 h 45 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $330
Train from Pittsburgh Amtrak to New York Penn Station
Ave. Duration
9 h 20 min
Frequency
Once daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pittsburgh, Pa to Columbus, Oh
Ave. Duration
3 h 20 min
Frequency
Hourly
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $40
Flexible
$40 - $55
Bus from Columbus, Oh to Winston Salem, Nc
Ave. Duration
10 h 35 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Bus from Pittsburgh, Pa to Washington, Dc
Ave. Duration
7 h 35 min
Frequency
Hourly
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90
Bus from Washington, Dc to Winston Salem, Nc
Ave. Duration
10 h
Frequency
Every 4 hours
Estimated price
$40 - $100
Website
greyhound.com
Economy
$40 - $65
Flexible
$75 - $100
NYTN Bus
Website
nytnbus.com
Bus from New York, NY to Knoxville, TN
Ave. Duration
11 h 30 min
Frequency
Once daily
Estimated price
$100 - $200
Schedules at
nytnbus.com

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Trips to Great Smoky Mountains National Park