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There are 6 ways to get from Pittsburgh to Great Smoky Mountains National Park by plane, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, travel  •  6 h 18 min

  1. Fly from Pittsburgh (PIT) to Knoxville (TYS) PIT - TYS
  2. Travel from Knoxville to Great Smoky Mountains National Park

5 alternative options

Fly to Greenville/Spartanburg, travel  •  7 h 43 min

  1. Fly from Pittsburgh (PIT) to Greenville/Spartanburg (GSP) PIT - GSP
  2. Travel from Greenville/Spartanburg to Great Smoky Mountains National Park

Bus, travel via Durham, Nc  •  21 h 5 min

  1. Take the bus from Pittsburgh, PA to Washington DC
  2. Take the bus from Washington to Durham, NC
  3. Take the bus from Durham, Nc to Asheville, Nc
  4. Travel from Asheville, Nc to Great Smoky Mountains National Park

Train, bus, travel via Greensboro Amtrak Station  •  21 h 25 min

  1. Take the train from Pittsburgh Amtrak Station to Washington Union Station
  2. Take the train from Washington Union Station to Greensboro Amtrak Station
  3. Take the bus from Greensboro, Nc to Asheville, Nc
  4. Travel from Asheville, Nc to Great Smoky Mountains National Park

Bus NYTN Bus, travel  •  22 h 46 min

  1. Take the bus from Pittsburgh, PA to State College, PA
  2. Take the bus from North Atherton Place At Mcdonalds to New York
  3. Take the bus from New York, NY to Knoxville, TN
  4. Travel from Knoxville, TN to Great Smoky Mountains National Park

Train, bus NYTN Bus, travel  •  23 h 35 min

  1. Take the train from Pittsburgh Amtrak Station to New York Penn Station
  2. Take the bus from New York, NY to Knoxville, TN
  3. Travel from Knoxville, TN to Great Smoky Mountains National Park

Questions & Answers

The distance between Pittsburgh and Great Smoky Mountains National Park is 387 miles.

The best way to get from Pittsburgh to Great Smoky Mountains National Park without a car is to bus and travel which takes 21 h 5 min and costs .

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It takes approximately 6 h 18 min to get from Pittsburgh to Great Smoky Mountains National Park, including transfers.

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There is no direct flight from Pittsburgh Airport to Knoxville Airport. The quickest flight takes 3 h 40 min and has one stopover.

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United Airlines, American Airlines and Delta offer flights from Pittsburgh Airport to Knoxville Airport.

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There are 1701+ hotels available in Great Smoky Mountains National Park. Prices start at $62 USD per night.

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The best way to get from Pittsburgh to Pittsburgh Airport is to bus which takes 39 min and costs $3.

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Map of how to get from Pittsburgh to Great Smoky Mountains National Park.
Launch map view
  • Distance: 387.4 miles
  • Duration: 6 h 18 min

What companies run services between Pittsburgh, PA, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Pittsburgh to Great Smoky Mountains National Park. However, you can take the bus to Pgh Internl Airport Lower Level, take the walk to Pittsburgh airport, fly to Knoxville, then take the travel to Great Smoky Mountains National Park. Alternatively, you can take the bus to Pgh Internl Airport Lower Level, take the walk to Pittsburgh airport, fly to Greenville/Spartanburg, then take the travel to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Pittsburgh to Knoxville via Atlanta
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$200 - $1,000
Flights from Pittsburgh to Knoxville via Detroit
Ave. Duration
4 h 9 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $1,000
Flights from Pittsburgh to Knoxville via New York La Guardia
Ave. Duration
5 h 9 min
When
Tuesday, Wednesday, Thursday and Friday
Estimated price
$220 - $1,100
Flights from Pittsburgh to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 3 min
When
Monday to Friday
Estimated price
$200 - $850
Flights from Pittsburgh to Greenville/Spartanburg via Detroit
Ave. Duration
4 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $850
American Airlines
Website
aa.com
Flights from Pittsburgh to Knoxville via Charlotte
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$200 - $1,000
Flights from Pittsburgh to Knoxville via Reagan Washington
Ave. Duration
3 h 58 min
When
Monday to Friday
Estimated price
$210 - $1,100
Flights from Pittsburgh to Knoxville via Philadelphia
Ave. Duration
5 h 21 min
When
Tuesday
Estimated price
$230 - $1,100
Flights from Pittsburgh to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$200 - $370
Flights from Pittsburgh to Greenville/Spartanburg via Reagan Washington
Ave. Duration
4 h
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $370
Flights from Pittsburgh to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 18 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$200 - $370
United Airlines
Website
united.com
Flights from Pittsburgh to Knoxville via Washington Dulles
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$220 - $1,100
Flights from Pittsburgh to Knoxville via Newark
Ave. Duration
5 h
When
Monday to Friday
Estimated price
$250 - $1,200
Flights from Pittsburgh to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$200 - $700
Southwest Airlines
Website
southwest.com
Flights from Pittsburgh to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$260 - $950
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Pittsburgh Amtrak Station to Washington Union Station
Ave. Duration
7 h 45 min
Frequency
Once daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Train from Washington Union Station to Greensboro Amtrak Station
Ave. Duration
5 h 45 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $330
Train from Pittsburgh Amtrak Station to New York Penn Station
Ave. Duration
9 h 25 min
Frequency
Once daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Pittsburgh, PA to Washington DC
Ave. Duration
6 h 25 min
Frequency
Once daily
Estimated price
$27 - $40
Book at
megabus.com
Bus from Washington to Durham, NC
Ave. Duration
5 h 35 min
Frequency
4 times a day
Estimated price
$25 - $40
Book at
megabus.com
Bus from Pittsburgh, PA to State College, PA
Ave. Duration
3 h
Frequency
Every 4 hours
Estimated price
$14 - $25
Book at
megabus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Durham, Nc to Asheville, Nc
Ave. Duration
5 h 20 min
Frequency
Once daily
Estimated price
$27 - $65
Website
greyhound.com
Economy
$27 - $45
Flexible
$50 - $65
Bus from Greensboro, Nc to Asheville, Nc
Ave. Duration
4 h 10 min
Frequency
Once daily
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Shun Feng Inc
Phone
(617) 354-2101
Bus from North Atherton Place At Mcdonalds to New York
Ave. Duration
4 h 50 min
Frequency
4 times a week
Estimated price
$35
Schedules at
gotobus.com
NYTN Bus
Website
nytnbus.com
Bus from New York, NY to Knoxville, TN
Ave. Duration
11 h 30 min
Frequency
Once daily
Estimated price
$100 - $200
Schedules at
nytnbus.com

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Trips to Great Smoky Mountains National Park