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How to get fromPittsburgh to Des Moinesby plane, train, bus, bus (Greyhound, Flixbus), car or bus (Flixbus, Greyhound)

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There are 9 ways to get from Pittsburgh to Des Moines by plane, train, bus, bus (Greyhound, Flixbus), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pittsburgh International Airport to Des Moines

    best
    1. Fly from Pittsburgh International Airport (PIT) to Des Moines (DSM)plane plane PIT - DSM
    6h 51m
    $179–915
  2. Fly Pittsburgh International Airport to Fort Dodge Municipal Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Fort Dodge Municipal Airport (FOD)plane plane PIT - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    10h 18m
    $96–463
  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    17h 29m
    $105–228
  4. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    17h 54m
    $98–244
  5. Drive 775.6 mi

    1. Drive from Pittsburgh to Des Moinescar car 775.6 mi
    12h 49m
    $142–205
  6. Train to Johnstown-Cambria County Airport, fly to Des Moines

    1. Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Des Moines (DSM)plane plane JST - DSM
    11h 16m
    $200–911
  7. Bus to Morgantown Municipal Airport, fly to Des Moines

    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Fly from Morgantown Municipal Airport (MGW) to Des Moines (DSM)plane plane MGW - DSM
    11h 25m
    $161–852
  8. Bus to Akron, fly to Des Moines

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Des Moines (DSM)plane plane CAK - DSM
    9h 46m
    $178–883
  9. Bus via Auburn Gresham

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    20h
    $108–203

Pittsburgh to Des Moines by train, foot, and bus

Calendar7Weekly Services
Duration17h 29mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Des Moines, IA, USA?

United Airlines, American Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Des Moines via Chicago Bus Station in around 17h 54m.

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