There are 9 ways to get from Pittsburgh to Des Moines by plane, train, bus, bus (Greyhound, Flixbus), car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pittsburgh International Airport to Des Moines
best- Fly from Pittsburgh International Airport (PIT) to Des Moines (DSM)plane PIT - DSM
6h 51m$179–915Fly Pittsburgh International Airport to Fort Dodge Municipal Airport, drive
cheapest- Fly from Pittsburgh International Airport (PIT) to Fort Dodge Municipal Airport (FOD)plane PIT - FOD
- Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar
10h 18m$96–463Train, bus
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
17h 29m$105–228Bus
- Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus Greyhound US0164
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
17h 54m$98–244Drive 775.6 mi
- Drive from Pittsburgh to Des Moinescar 775.6 mi
12h 49m$142–205Train to Johnstown-Cambria County Airport, fly to Des Moines
- Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain
- Fly from Johnstown-Cambria County Airport (JST) to Des Moines (DSM)plane JST - DSM
11h 16m$200–911Bus to Morgantown Municipal Airport, fly to Des Moines
- Take the bus from Pittsburgh Greyhound to Westover Terminalbus
- Fly from Morgantown Municipal Airport (MGW) to Des Moines (DSM)plane MGW - DSM
11h 25m$161–852Bus to Akron, fly to Des Moines
- Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus
- Fly from Akron (CAK) to Des Moines (DSM)plane CAK - DSM
9h 46m$178–883Bus via Auburn Gresham
- Take the bus from Pittsburgh Intermodal Station to Chicagobus FlixBus N2640
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
20h$108–203
Pittsburgh to Des Moines by train, foot, and bus
Questions & Answers
The cheapest way to get from Pittsburgh to Des Moines is to train and bus which costs $100 - $230 and takes 17h 29m.
The fastest way to get from Pittsburgh to Des Moines is to fly which takes 6h 51m and costs $170 - $950.
No, there is no direct bus from Pittsburgh station to Des Moines. However, there are services departing from Pittsburgh Intermodal Station and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 17h 54m.
The distance between Pittsburgh and Des Moines is 737 miles. The road distance is 780.2 miles.
The best way to get from Pittsburgh to Des Moines without a car is to train and bus which takes 17h 29m and costs $100 - $230.
It takes approximately 6h 51m to get from Pittsburgh to Des Moines, including transfers.
Pittsburgh to Des Moines bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
The best way to get from Pittsburgh to Des Moines is to fly which takes 6h 51m and costs $170 - $950. Alternatively, you can bus, which costs $95 - $250 and takes 17h 54m.
Pittsburgh to Des Moines bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Des Moines is 1h behind Pittsburgh. It is currently 12:06 PM in Pittsburgh and 11:06 AM in Des Moines.
What companies run services between Pittsburgh, PA, USA and Des Moines, IA, USA?
United Airlines, American Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Des Moines via Chicago Bus Station in around 17h 54m.
- Website
- united.com
Flights from Pittsburgh International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–900
Flights from Johnstown-Cambria County Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 8h 22m
- When
- Every day
- Estimated price
- $150–850
Flights from Pittsburgh International Airport to Fort Dodge Municipal Airport via Chicago O'Hare
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $80–440
Flights from Morgantown Municipal Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 10h 23m
- When
- Every day
- Estimated price
- $140–800
Flights from Akron to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $130–800
- Website
- aa.com
Flights from Pittsburgh International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $160–900
Flights from Pittsburgh International Airport to Des Moines via Reagan Washington
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Akron to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $130–800
Flights from Akron to Des Moines via Charlotte
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Akron to Des Moines via Reagan Washington
- Ave. Duration
- 8h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
- Website
- delta.com
Flights from Pittsburgh International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Pittsburgh International Airport to Des Moines via Detroit
- Ave. Duration
- 7h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–950
- Website
- southwest.com
Flights from Pittsburgh International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 7h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–900
- Website
- allegiantair.com
Flights from Akron to Des Moines via Jacksonville
- Ave. Duration
- 5h 33m
- When
- Thursday
- Estimated price
- $260–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Johnstown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $19–22
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–95
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to Chicago Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- Twice daily
- Estimated price
- $55–150
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago
- Ave. Duration
- 10h 55m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
- Phone
- +1 304-291-7433
- Website
- busride.org
Bus from Pittsburgh Greyhound to Westover Terminal
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $3–30
- Website
- https://www.busride.org
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Pittsburgh to Des Moines is 780 miles. It takes approximately 12h 49m to drive from Pittsburgh to Des Moines.
Book your Pittsburgh to Des Moines bus tickets online with Omio and FlixBus.
There are 239+ hotels available in Des Moines.






