There are 7 ways to get from Pittsburgh to Des Moines by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Des Moines  •  6 h 46 min

  1. Fly from Pittsburgh (PIT) to Des Moines (DSM) PIT - DSM

$175 - $855

Cheapest option

Bus, Megabus  •  18 h 55 min

  1. Take the bus from Pittsburgh, Pa to Cleveland, Oh
  2. Take the Megabus from Cleveland to Chicago, IL
  3. Take the bus from Chicago, IL to Des Moines, IA

$98 - $178

5 alternative options

Fly to Waterloo, bus  •  11 h 43 min

  1. Fly from Pittsburgh (PIT) to Waterloo (ALO) PIT - ALO
  2. Take the bus from Waterloo, IA to Des Moines, IA

$272 - $1,086

Train, bus  •  17 h 48 min

  1. Take the train from Pittsburgh Amtrak to Chicago Union Station Capitol Limited
  2. Take the bus from Chicago, IL to Des Moines, IA 1205 / ...

$120 - $281

Train, bus via Ottumwa, IA  •  19 h 19 min

  1. Take the train from Pittsburgh Amtrak to Chicago Union Station
  2. Take the train from Chicago Union Station to Ottumwa Amtrak
  3. Take the bus from Ottumwa, IA to Monroe, IA
  4. Take the bus from Monroe, IA to Des Moines, IA

$173 - $406

Bus  •  23 h 31 min

  1. Take the bus from Pittsburgh, Pa to Kansas City, Mo 1683 / ...
  2. Take the bus from Kansas City, MO to Des Moines, IA 802 / ...

$122 - $257

Drive  •  12 h 40 min

  1. Drive from Pittsburgh to Des Moines 782.3 miles

$75 - $120

Questions & Answers

The cheapest way to get from Pittsburgh to Des Moines is to drive which costs $75 - $120 and takes 12 h 40 min.

More details

The quickest way to get from Pittsburgh to Des Moines is to fly which costs $170 - $900 and takes 6 h 46 min.

More details

No, there is no direct bus from Pittsburgh to Des Moines. However, there are services departing from Pittsburgh, Pa and arriving at Des Moines, IA via Chester Av & E 15Th St, Cleveland and Chicago, IL. The journey, including transfers, takes approximately 18 h 55 min.

More details

The distance between Pittsburgh and Des Moines is 718 miles. The road distance is 782.3 miles.

Get driving directions

The best way to get from Pittsburgh to Des Moines without a car is to train and bus which takes 17 h 48 min and costs $120 - $290.

More details

It takes approximately 6 h 46 min to get from Pittsburgh to Des Moines, including transfers.

More details

Pittsburgh to Des Moines bus services, operated by Greyhound USA, depart from Pittsburgh, Pa station.

More details

The best way to get from Pittsburgh to Des Moines is to fly which takes 6 h 46 min and costs $170 - $900. Alternatively, you can bus and Megabus, which costs $95 - $180 and takes 18 h 55 min.

Mode details

Map of how to get from Pittsburgh to Des Moines.
Launch map view
  • Distance: 717.6 miles
  • Duration: 6 h 46 min

What companies run services between Pittsburgh, PA, USA and Des Moines, IA, USA?

Southwest Airlines, Delta and two other airlines fly from Pittsburgh to Des Moines hourly. Alternatively, you can take a bus from Pittsburgh to Des Moines via Cleveland, Oh, Chester Av & E 15Th St, Stephanie Tubbs Jones Transit Center Stop #9, Cleveland, Chicago, IL, and Chicago, IL in around 18 h 55 min.

Airlines
American Airlines
Website
aa.com
Flights from Pittsburgh to Des Moines via Chicago O'Hare
Ave. Duration
4 h 58 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $850
Flights from Pittsburgh to Des Moines via Charlotte
Ave. Duration
5 h 27 min
When
Every day
Estimated price
$210 - $950
Flights from Pittsburgh to Des Moines via Philadelphia
Ave. Duration
5 h 41 min
When
Every day
Estimated price
$220 - $950
Flights from Pittsburgh to Waterloo via Chicago O'Hare
Ave. Duration
4 h 51 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Pittsburgh to Waterloo via Charlotte, Chicago O'Hare
Ave. Duration
7 h 5 min
When
Every day
Estimated price
$260 - $1,100
Flights from Pittsburgh to Waterloo via Reagan Washington, Chicago O'Hare
Ave. Duration
7 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,100
Flights from Pittsburgh to Waterloo via New York La Guardia, Chicago O'Hare
Ave. Duration
7 h 41 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,200
Flights from Pittsburgh to Waterloo via Philadelphia, Chicago O'Hare
Ave. Duration
7 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,100
Delta
Website
delta.com
Flights from Pittsburgh to Des Moines via Detroit
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$170 - $850
Flights from Pittsburgh to Des Moines via Minneapolis
Ave. Duration
5 h 7 min
When
Every day
Estimated price
$180 - $900
Flights from Pittsburgh to Des Moines via Atlanta
Ave. Duration
5 h 8 min
When
Every day
Estimated price
$200 - $950
United Airlines
Website
united.com
Flights from Pittsburgh to Des Moines via Chicago O'Hare
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$190 - $900
Southwest Airlines
Website
southwest.com
Flights from Pittsburgh to Des Moines via St. Louis
Ave. Duration
3 h 50 min
When
Saturday
Estimated price
$200 - $850
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Pittsburgh Amtrak to Chicago Union Station
Ave. Duration
9 h 46 min
Frequency
Once daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $110
Flexi Coach Seat
$130 - $190
Business Coach Seat
$140 - $210
Room
$320 - $440
Train from Chicago Union Station to Ottumwa Amtrak
Ave. Duration
4 h 53 min
Frequency
Once daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Burlington Trailways
Website
burlingtontrailways.com
Bus from Waterloo, IA to Des Moines, IA
Ave. Duration
4 h 30 min
Frequency
Once daily
Estimated price
$40 - $60
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Chicago, IL to Des Moines, IA
Ave. Duration
6 h 50 min
Frequency
Every 3 hours
Estimated price
$45 - $80
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Ottumwa, IA to Monroe, IA
Ave. Duration
55 min
Frequency
Once a week
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Monroe, IA to Des Moines, IA
Ave. Duration
45 min
Frequency
Once a week
Estimated price
$23 - $35
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pittsburgh, Pa to Cleveland, Oh
Ave. Duration
2 h 50 min
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Pittsburgh, Pa to Kansas City, Mo
Ave. Duration
20 h
Frequency
Hourly
Estimated price
$80 - $210
Website
greyhound.com
Economy
$80 - $140
Flexible
$150 - $210
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Kansas City, MO to Des Moines, IA
Ave. Duration
2 h 55 min
Frequency
Hourly
Estimated price
$40 - $55
Book at
jeffersonlines.com

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