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How to get fromPittsburgh to Depewby bus (Greyhound), train (Amtrak), car, plane or bus

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There are 5 ways to get from Pittsburgh to Depew by bus (Greyhound), train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Erie

    best
    1. Take the bus from Pittsburgh Intermodal Station to Eriebus bus Greyhound US0440s
    2. Take the bus from Erie, PA to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    7h 54m
    $37–103

  2. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    2. Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain train Lake Shore Limited
    8h
    $56–157

  3. Drive 218.8 mi

    1. Drive from Pittsburgh to Depewcar car 218.8 mi
    3h 49m
    $40–58

  4. Fly

    1. Fly from Pittsburgh International Airport (PIT) to Buffalo Niagara International Airport (BUF)plane plane PIT - BUF
    6h 1m
    $180–1,022

  5. Bus

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    9h 49m
    $46–176

Pittsburgh to Depew by bus

Calendar7Weekly Buses
Duration7h 54mAverage Duration
Ticket$37Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Depew, NY, USA?

You can take a bus from Pittsburgh Intermodal Station to Broadway & Elwood Avenue via Erie, Erie, PA, and Ellicott Street & MTC Static in around 7h 54m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Broadway & Canton Street via Cleveland Amtrak, Buffalo Depew Station, and Broadway & Dick Road in around 8h.

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