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How to get fromPittsburgh to Depewby train (Amtrak), bus (Greyhound), car, plane or bus

Find Transport to Depew

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There are 5 ways to get from Pittsburgh to Depew by train (Amtrak), bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Pittsburgh Amtrak Station to Cleveland AmtraktrainFloridian
    2. Take the train from Cleveland Amtrak to Buffalo Depew StationtrainLake Shore Limited
    8h
    $60–163

  2. Bus via Erie

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to EriebusGreyhound US0440s
    2. Take the bus from Erie to BuffalobusGreyhound US0170
    8h 14m
    $40–104

  3. Drive 218.8 mi

    1. Drive from Pittsburgh to Depewcar218.8 mi
    3h 47m
    $40–58

  4. Fly

    1. Fly from Pittsburgh International Airport (PIT) to Buffalo Niagara International Airport (BUF)planePIT - BUF
    5h 24m
    $200–1,097

  5. Bus

    1. Take the bus from Pittsburgh to BuffalobusFab510
    9h 49m
    $46–176

Pittsburgh to Depew by train and bus (Amtrak)

Calendar5Weekly Services
Duration8hAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Depew, NY, USA?

You can take a train from Pittsburgh Amtrak Station to Broadway & Canton Street via Cleveland Amtrak, Buffalo Depew Station, and Broadway & Dick Road in around 8h. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Broadway & Elwood Avenue via Erie and Ellicott Street & MTC Static in around 8h 14m.

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