There are 4 ways to get from Pittsburgh to Defiance by train (Amtrak), bus, taxi, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Pittsburgh Amtrak Station to ToledoFloridian
- Take the train from Toledo to Bryan Amtrak StationLake Shore Limited
7h 29m$98–240Drive 275 mi
cheapest- Drive from Pittsburgh to Defiance275 mi
4h 33m$51–73Bus, taxi
- Take the bus from Pittsburgh Intermodal Station to Columbus Bus Station
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Take the taxi from Delphos to Defiance
7h 30m$133–228Fly, taxi
- Fly from Pittsburgh International Airport (PIT) to Fort Wayne International Airport (FWA)PIT - FWA
- Take the taxi from Fort Wayne International Airport (FWA) to Defiance
6h 56m$192–504
Pittsburgh International Airport (PIT) to Fort Wayne International Airport (FWA) flights
Questions & Answers
The cheapest way to get from Pittsburgh to Defiance is to drive which costs $50 - $75 and takes 4h 33m.
The fastest way to get from Pittsburgh to Defiance is to drive which takes 4h 33m and costs $50 - $75.
The distance between Pittsburgh and Defiance is 319 miles. The road distance is 276.6 miles.
The best way to get from Pittsburgh to Defiance without a car is to train which takes 7h 29m and costs $95 - $240.
It takes approximately 7h 29m to get from Pittsburgh to Defiance, including transfers.
Yes, the driving distance between Pittsburgh to Defiance is 277 miles. It takes approximately 4h 33m to drive from Pittsburgh to Defiance.
There are 12+ hotels available in Defiance.
What companies run services between Pittsburgh, PA, USA and Defiance, OH, USA?
You can take a train from Pittsburgh Amtrak Station to Defiance via Toledo and Bryan Amtrak Station in around 7h 29m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Pittsburgh International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $65–370
Flights from Pittsburgh International Airport to Fort Wayne International Airport via Charlotte
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $80–420
- Website
- delta.com
Flights from Pittsburgh International Airport to Fort Wayne International Airport via Detroit
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $50–330
Flights from Pittsburgh International Airport to Fort Wayne International Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $95–460
- Website
- united.com
Flights from Pittsburgh International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $65–370
- Website
- allegiantair.com
Flights from Pittsburgh International Airport to Fort Wayne International Airport via St. Petersburg
- Ave. Duration
- 8h 17m
- When
- Wednesday
- Estimated price
- $140–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Toledo
- Ave. Duration
- 5h 9m
- Frequency
- Once daily
- Estimated price
- $35–110
- Website
- https://www.amtrak.com/home.html
Train from Toledo to Bryan Amtrak Station
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $6–60
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $16–27
- Coach Seat short notice purchase
- $6–60
- Business - advance purchase
- $9–80
- Business Class
- $16–170
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Pittsburgh Intermodal Station to Columbus Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 888 954 6287
- gobus@hapcap.org
- Website
- ridegobus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Delphos
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://ridegobus.com/
- Book at
- https://booking.ridegobus.com/
- Ave. Duration
- 1h 2m
- Estimated price
- $85–180
Black and White Transportation
- Phone
- +1-419-536-8294
- Website
- bwtransportation.com
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide












