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How to get fromPittsburgh to Defianceby bus (Greyhound, Amtrak), train (Amtrak), car, plane, taxi, train, or bus

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There are 5 ways to get from Pittsburgh to Defiance by bus (Greyhound, Amtrak), train (Amtrak), car, plane, taxi, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Pittsburgh Intermodal Station to Toledo Bus Stopbus bus Greyhound US0164 / ...
    2. Take the bus from Toledo to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    6h 50m
    $112–172

  2. Drive 268.2 mi

    cheapest
    1. Drive from Pittsburgh to Defiancecar car 268.2 mi
    4h 53m
    $49–71

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Toledotrain train Floridian
    2. Take the train from Toledo to Bryan Amtrak Stationtrain train Lake Shore Limited
    7h 29m
    $152–263

  4. Fly, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Fort Wayne International Airport (FWA)plane plane PIT - FWA
    2. Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi taxi
    6h 26m
    $200–552

  5. Train, bus (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Toledotrain train Floridian
    2. Take the bus from Toledo to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    7h 29m
    $156–263

Pittsburgh International Airport (PIT) to Fort Wayne International Airport (FWA) flights

Calendar89Weekly Planes
Duration5h 17mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Defiance.ExpandLaunch map view
  • Distance: 316.9 mi
  • Duration: 6h 50m

What companies run services between Pittsburgh, PA, USA and Defiance, OH, USA?

You can take a bus from Pittsburgh Intermodal Station to Defiance via Toledo and Bryan Amtrak Station in around 6h 50m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Defiance via Toledo and Bryan Amtrak Station in around 7h 29m.

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