There are 6 ways to get from Pittsburgh to Cambridge by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Boston  •  3 h 39 min

  1. Fly from Pittsburgh (PIT) to Boston (BOS) PIT - BOS

$101 - $271

Cheapest option

Bus Megabus  •  12 h 55 min

  1. Take the bus from Pittsburgh, PA to New York, NY Via State College
  2. Take the bus from New York, NY to Boston, MA

$57 - $90

4 alternative options

Fly to Manchester, bus  •  7 h 10 min

  1. Fly from Pittsburgh (PIT) to Manchester (MHT) PIT - MHT
  2. Take the bus from Manchester Arpt to Boston, Ma

$173 - $352

Train  •  14 h 3 min

  1. Take the train from Pittsburgh Amtrak to New York Penn Station Pennsylvanian
  2. Take the train from New York Penn Station to Boston Back Bay Station Acela Express / ...

$189 - $523

Bus Greyhound USA  •  15 h 16 min

  1. Take the bus from Pittsburgh, Pa to New York, Ny 1684 / ...
  2. Take the bus from New York, Ny to Boston, Ma 2504 / ...

$68 - $174

Drive  •  10 h 6 min

  1. Drive from Pittsburgh to Cambridge 584.8 miles

$55 - $85

Questions & Answers

The cheapest way to get from Pittsburgh to Cambridge is to drive which costs $55 - $85 and takes 10 h 6 min.

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The quickest way to get from Pittsburgh to Cambridge is to fly which costs $100 - $280 and takes 3 h 39 min.

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No, there is no direct bus from Pittsburgh to Cambridge. However, there are services departing from Pittsburgh, PA and arriving at Boston, MA via New York, NY. The journey, including transfers, takes approximately 12 h 55 min.

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No, there is no direct train from Pittsburgh to Cambridge station. However, there are services departing from Pittsburgh Amtrak and arriving at Boston Back Bay Station via New York Penn Station. The journey, including transfers, takes approximately 14 h 3 min.

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The distance between Pittsburgh and Cambridge is 482 miles. The road distance is 584.8 miles.

Get driving directions

The best way to get from Pittsburgh to Cambridge without a car is to bus which takes 12 h 55 min and costs $55 - $90.

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It takes approximately 3 h 39 min to get from Pittsburgh to Cambridge, including transfers.

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Pittsburgh to Cambridge bus services, operated by Megabus, depart from Pittsburgh, PA station.

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Pittsburgh to Cambridge train services, operated by Amtrak, depart from Pittsburgh Amtrak station.

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The best way to get from Pittsburgh to Cambridge is to fly which takes 3 h 39 min and costs $100 - $280. Alternatively, you can bus, which costs $55 - $90 and takes 12 h 55 min, you could also train, which costs $180 - $550 and takes 14 h 3 min.

Mode details

Map of how to get from Pittsburgh to Cambridge.
Launch map view
  • Distance: 482.2 miles
  • Duration: 3 h 39 min

What companies run services between Pittsburgh, PA, USA and Cambridge, MA, USA?

JetBlue Airways, Delta and four other airlines fly from Pittsburgh to Cambridge hourly. Alternatively, you can take a bus from Pittsburgh to Cambridge via New York, NY in around 12 h 55 min.

Airlines
American Airlines
Website
aa.com
Flights from Pittsburgh to Boston
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$120 - $500
Flights from Pittsburgh to Boston via Reagan Washington
Ave. Duration
3 h 22 min
When
Every day
Estimated price
$120 - $500
Flights from Pittsburgh to Manchester via Philadelphia
Ave. Duration
4 h 26 min
When
Every day
Estimated price
$160 - $800
Flights from Pittsburgh to Manchester via Reagan Washington
Ave. Duration
4 h 34 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $800
Flights from Pittsburgh to Manchester via Charlotte
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$200 - $900
Southwest Airlines
Website
southwest.com
Flights from Pittsburgh to Boston via Baltimore
Ave. Duration
3 h 30 min
When
Sunday
Estimated price
$180 - $650
Flights from Pittsburgh to Manchester via Baltimore
Ave. Duration
4 h 41 min
When
Every day
Estimated price
$180 - $800
Flights from Pittsburgh to Manchester via Chicago Midway
Ave. Duration
5 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $900
Delta
Website
delta.com
Flights from Pittsburgh to Boston
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$130 - $550
Flights from Pittsburgh to Manchester via Detroit
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$170 - $850
Flights from Pittsburgh to Manchester via New York La Guardia
Ave. Duration
5 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$150 - $800
JetBlue Airways
Website
jetblue.com
Flights from Pittsburgh to Boston
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$140 - $550
United Airlines
Website
united.com
Flights from Pittsburgh to Boston via Washington Dulles
Ave. Duration
3 h 27 min
When
Every day
Estimated price
$140 - $650
Flights from Pittsburgh to Manchester via Newark
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$260 - $460
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Pittsburgh Amtrak to New York Penn Station
Ave. Duration
9 h 25 min
Frequency
Once daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Boston Back Bay Station
Ave. Duration
3 h 38 min
Frequency
Every 3 hours
Estimated price
$120 - $340
Website
amtrak.com
Business Seat
$120 - $260
First Class Seat
$220 - $340
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Manchester Arpt to Boston, Ma
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$12 - $26
Website
greyhound.com
Economy
$12 - $17
Flexible
$20 - $26
Bus from Pittsburgh, Pa to New York, Ny
Ave. Duration
10 h 30 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from New York, Ny to Boston, Ma
Ave. Duration
4 h 20 min
Frequency
Every 30 minutes
Estimated price
$25 - $65
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $65
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Pittsburgh, PA to New York, NY
Ave. Duration
7 h 50 min
Frequency
4 times a day
Estimated price
$35 - $55
Book at
megabus.com
Bus from New York, NY to Boston, MA
Ave. Duration
4 h 15 min
Frequency
Hourly
Estimated price
$21 - $35
Book at
megabus.com
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from New York City, NY - Port Authority Bus Terminal to Boston, MA - South Station
Ave. Duration
4 h 15 min
Frequency
Hourly
Estimated price
$21 - $40
Website
peterpanbus.com

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More Questions & Answers

The quickest flight from Pittsburgh Airport to Boston Airport is the direct flight which takes 1 h 32 min.

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Pittsburgh to Cambridge bus services, operated by Megabus, arrive at Boston, MA station.

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Pittsburgh to Cambridge train services, operated by Amtrak Acela Express, arrive at Boston Back Bay Station.

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Yes, the driving distance between Pittsburgh to Cambridge is 585 miles. It takes approximately 10 h 6 min to drive from Pittsburgh to Cambridge.

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United Airlines, Southwest Airlines, Delta and two other airlines offer flights from Pittsburgh Airport to Boston Airport.

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Book your Pittsburgh to Cambridge train tickets online with Rome2rio.

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There are 769+ hotels available in Cambridge. Prices start at $135 USD per night.

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The best way to get from Pittsburgh to Pittsburgh Airport is to bus which takes 40 min and costs $3.

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