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There are 5 ways to get from Pittsburgh to Buffalo–Depew Station by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6h 50m

  1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtrak Station Capitol Limited
  2. Take the train from Cleveland Amtrak Station to Buffalo Depew Station Lake Shore Limited

$76 - $176

Cheapest option

Bus Greyhound USA  •  7h 49m

  1. Take the bus from Pittsburgh, Pa to Erie, Pa 4646 / ...
  2. Take the bus from Erie, Pa to Buffalo, Ny 212 / ...

$39 - $86

3 alternative options

Bus Fullington Trailways  •  9h 43m

  1. Take the bus from Pittsburgh, PA to Dubois, PA 710 Pittsburgh / ...
  2. Take the bus from Dubois, PA to Buffalo, NY 510 DuBois

$71 - $126

Drive  •  3h 47m

  1. Drive from Pittsburgh to Buffalo–Depew Station 220.2 miles

$21 - $35

Fly  •  5h 17m

  1. Fly from Pittsburgh (PIT) to Buffalo (BUF) PIT - BUF

$167 - $821

Questions & Answers

The cheapest way to get from Pittsburgh to Buffalo–Depew Station is to drive which costs $21 - $35 and takes 3h 47m.

More details

The quickest way to get from Pittsburgh to Buffalo–Depew Station is to drive which costs $21 - $35 and takes 3h 47m.

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No, there is no direct bus from Pittsburgh to Buffalo–Depew Station. However, there are services departing from Pittsburgh, Pa and arriving at Walden Ave & 2929 Walden via Erie, Pa, Ellicott St & North Division St and Galleria Drway & Green Parking Entrance. The journey, including transfers, takes approximately 7h 49m.

More details

No, there is no direct train from Pittsburgh station to Buffalo–Depew Station station. However, there are services departing from Pittsburgh Amtrak Station and arriving at Buffalo Depew Station via Cleveland Amtrak Station. The journey, including transfers, takes approximately 6h 50m.

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The distance between Pittsburgh and Buffalo–Depew Station is 184 miles. The road distance is 220.2 miles.

Get driving directions

The best way to get from Pittsburgh to Buffalo–Depew Station without a car is to train which takes 6h 50m and costs $75 - $180.

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It takes approximately 6h 50m to get from Pittsburgh to Buffalo–Depew Station, including transfers.

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Pittsburgh to Buffalo–Depew Station bus services, operated by Greyhound USA, depart from Pittsburgh, Pa station.

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Pittsburgh to Buffalo–Depew Station train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.

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The best way to get from Pittsburgh to Buffalo–Depew Station is to train which takes 6h 50m and costs $75 - $180. Alternatively, you can bus, which costs $35 - $90 and takes 7h 49m, you could also fly, which costs $160 - $850 and takes 5h 17m.

Mode details

Map of how to get from Pittsburgh to Buffalo–Depew Station.
Launch map view
  • Distance: 183.6 miles
  • Duration: 6h 50m

What companies run services between Pittsburgh, PA, USA and Buffalo–Depew Station, NY, USA?

You can take a train from Pittsburgh to Buffalo–Depew Station via Cleveland Amtrak Station in around 6h 50m. Alternatively, you can take a bus from Pittsburgh to Buffalo–Depew Station via Erie, Pa, Buffalo, Ny, Ellicott St & North Division St, Galleria Drway & Green Parking Entrance, and Walden Ave & 2929 Walden in around 7h 49m.

Airlines
Delta
Website
delta.com
Flights from Pittsburgh to Buffalo via Detroit
Ave. Duration
3h 58m
When
Every day
Estimated price
$150 - $800
Flights from Pittsburgh to Buffalo via New York La Guardia
Ave. Duration
4h 17m
When
Monday to Saturday
Estimated price
$160 - $850
Flights from Pittsburgh to Buffalo via New York JFK
Ave. Duration
4h 29m
When
Saturday
Estimated price
$160 - $850
Flights from Pittsburgh to Buffalo via Boston
Ave. Duration
4h 56m
When
Monday to Friday
Estimated price
$180 - $900
American Airlines
Website
aa.com
Flights from Pittsburgh to Buffalo via Philadelphia
Ave. Duration
4h 6m
When
Every day
Estimated price
$170 - $850
Flights from Pittsburgh to Buffalo via Charlotte
Ave. Duration
4h 30m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $900
Flights from Pittsburgh to Buffalo via Reagan Washington
Ave. Duration
4h 42m
When
Every day
Estimated price
$160 - $850
United Airlines
Website
united.com
Flights from Pittsburgh to Buffalo via Washington Dulles
Ave. Duration
3h 46m
When
Every day
Estimated price
$170 - $850
Flights from Pittsburgh to Buffalo via Newark
Ave. Duration
4h 23m
When
Monday to Friday
Estimated price
$180 - $900
Flights from Pittsburgh to Buffalo via Chicago O'Hare
Ave. Duration
4h 22m
When
Every day
Estimated price
$200 - $950
JetBlue Airways
Website
jetblue.com
Flights from Pittsburgh to Buffalo via Boston
Ave. Duration
4h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $850
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Pittsburgh Amtrak Station to Cleveland Amtrak Station
Ave. Duration
2h 54m
Frequency
Once daily
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Train from Cleveland Amtrak Station to Buffalo Depew Station
Ave. Duration
2h 56m
Frequency
Twice daily
Estimated price
$40 - $95
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $100
Business Coach Seat
$65 - $95
Room
$190 - $270
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pittsburgh, Pa to Erie, Pa
Ave. Duration
3h 19m
Frequency
Twice daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Erie, Pa to Buffalo, Ny
Ave. Duration
1h 50m
Frequency
3 times a day
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Fullington Trailways
Phone
+1 800.942.8287
Website
fullingtontours.com
Bus from Pittsburgh, PA to Dubois, PA
Ave. Duration
2h 30m
Frequency
Twice daily
Estimated price
$27 - $50
Schedules at
fullingtontours.com
Book at
fab.tdstickets.com
Bus from Dubois, PA to Buffalo, NY
Ave. Duration
4h 40m
Frequency
Once daily
Estimated price
$40 - $75
Schedules at
fullingtontours.com
Book at
fab.tdstickets.com

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More Questions & Answers

There is no direct flight from Pittsburgh Airport to Buffalo Airport. The quickest flight takes 3h 31m and has one stopover.

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Pittsburgh to Buffalo–Depew Station bus services, operated by Greyhound USA, arrive at Buffalo, Ny station.

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Pittsburgh to Buffalo–Depew Station train services, operated by Amtrak, arrive at Buffalo Depew Station.

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Yes, the driving distance between Pittsburgh to Buffalo–Depew Station is 220 miles. It takes approximately 3h 47m to drive from Pittsburgh to Buffalo–Depew Station.

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JetBlue Airways, United Airlines, Delta and American Airlines offer flights from Pittsburgh Airport to Buffalo Airport.

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Book your Pittsburgh to Buffalo–Depew Station train tickets online with Rome2rio.

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There are 133+ hotels available in Buffalo–Depew Station. Prices start at $59 USD per night.

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The best way to get from Pittsburgh to Pittsburgh Airport is to bus which takes 39m and costs $3.

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