There are 9 ways to get from Pisa to Spa by plane, bus, train (Eurostar), train, car, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pisa International Airport to Brussels South Charleroi Airport, bus
best- Fly from Pisa International Airport (PSA) to Brussels South Charleroi Airport (CRL)PSA - CRL
- Take the bus from Charleroi Airport to Liège Rue du Plan Inclined
5h 14m€59–184Train via Chambéry
- Take the train from Pisa Centrale to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Milano Centrale
- Take the train from Milano Centrale to Chambery Challes Les EauxFr
- Take the train from Chambery Challes Les Eaux to Brussel-Zuid / Bruxelles-Midi
- Take the train from Bruxelles-Midi to PepinsterIc
16h 53m€202–492Train, bus
- Take the train from Pisa Centrale to Genova P.Za PrincipeFb / ...
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Mulhouse
- Take the train from Mulhouse Ville to LuxembourgTgv
- Take the train from Luxembourg to Trois-PontsIc
19h 18m€96–242Drive 1,055.9 km
- Drive from Pisa to Spa1,055.9 km
10h 52m€166–240Fly Pisa International Airport to Eindhoven Airport, train
- Fly from Pisa International Airport (PSA) to Eindhoven Airport (EIN)PSA - EIN
- Take the train from Eindhoven to Heerlen
5h 47m€85–312Train to Florence Peretola Airport, fly to Brussels Airport, train
- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Brussels Airport (BRU)FLR - BRU
- Take the train from Louvain to Verviers-Central
8h 7m€96–276Train to Florence Peretola Airport, fly to Düsseldorf International Airport, train
- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Düsseldorf International Airport (DUS)FLR - DUS
- Take the train from Duesseldorf Hbf to Aachen Hbf
9h 9m€132–363Train
- Take the train from Pisa Centrale to Milano CentraleIc
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim Hbf to Aachen HbfNj
21h 30m€180–315Bus
- Take the bus from Pisa to Milano, Autostazione Lampugnano1500 / ...
- Take the bus from Milano, Autostazione Lampugnano to Liège GuilleminsN473
21h 38m€64–157
Pisa to Spa by train
Questions & Answers
The cheapest way to get from Pisa to Spa is to bus which costs €60 - €160 and takes 21h 38m.
The fastest way to get from Pisa to Spa is to fly and bus which takes 5h 14m and costs €55 - €190.
No, there is no direct bus from Pisa to Spa. However, there are services departing from Pisa and arriving at SPA Place Royale via Milano, Autostazione Lampugnano, LIEGE Gare des Guillemins - Quai C and VERVIERS Gare Centrale. The journey, including transfers, takes approximately 21h 38m.
No, there is no direct train from Pisa to Spa. However, there are services departing from Pisa Centrale and arriving at Spa-Géronstère via Florence Santa Maria Novella, Milano Centrale, Chambery Challes Les Eaux, Bruxelles-Midi and Pepinster. The journey, including transfers, takes approximately 16h 53m.
The distance between Pisa and Spa is 996 km. The road distance is 1055.9 km.
The best way to get from Pisa to Spa without a car is to train via Chambéry which takes 16h 53m and costs €200 - €500.
It takes approximately 5h 14m to get from Pisa to Spa, including transfers.
Pisa to Spa bus services, operated by FlixBus, depart from Pisa station.
Pisa to Spa train services, operated by Trenitalia S.p.A., depart from Pisa Centrale station.
The best way to get from Pisa to Spa is to train via Chambéry which takes 16h 53m and costs €200 - €500. Alternatively, you can bus, which costs €60 - €160 and takes 21h 38m.
What companies run services between Pisa, Italy and Spa, Belgium?
You can take a train from Pisa Centrale to Spa-Géronstère via Florence Santa Maria Novella, Milano Centrale, Chambery Challes Les Eaux, Bruxelles-Midi, and Pepinster in around 16h 53m. Alternatively, you can take a bus from Pisa to SPA Place Royale via Milano, Autostazione Lampugnano, Liège Guillemins, LIEGE Gare des Guillemins - Quai C, and VERVIERS Gare Centrale in around 21h 38m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Brussels Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €140–450
Flights from Florence Peretola Airport to Brussels Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €110–200
Flights from Florence Peretola Airport to Düsseldorf International Airport via Frankfurt
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- €130–420
Flights from Florence Peretola Airport to Düsseldorf International Airport via Munich
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–420
- Website
- ryanair.com
Flights from Pisa International Airport to Brussels South Charleroi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–150
Flights from Pisa International Airport to Eindhoven Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Friday, and Sunday
- Estimated price
- €50–260
- Website
- swiss.com
Flights from Florence Peretola Airport to Brussels Airport via Zurich
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €110–200
Flights from Florence Peretola Airport to Düsseldorf International Airport via Zurich
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- €95–210
- Website
- vueling.com
Flights from Florence Peretola Airport to Brussels Airport
- Ave. Duration
- 2h
- When
- Thursday and Sunday
- Estimated price
- €45–170
- Website
- brusselsairlines.com
Flights from Florence Peretola Airport to Brussels Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- €110–200
- Website
- eurowings.com
Flights from Florence Peretola Airport to Düsseldorf International Airport
- Ave. Duration
- 1h 50m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €65–250
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €16–24
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Chambery Challes Les Eaux
- Ave. Duration
- 3h 27m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- €24–80
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–75
- Website
- https://www.italotreno.it/en
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Chambery Challes Les Eaux to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a week
- Estimated price
- €95–230
- Website
- https://www.eurostar.com/rw-en
Train from Duesseldorf Hbf to Aachen Hbf
- Ave. Duration
- 1h 13m
- Frequency
- 3 times a day
- Estimated price
- €35–80
- Website
- https://www.eurostar.com/rw-en
- Standard
- €35–55
- Comfort
- €40–55
- Premium
- €60–80
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Bruxelles-Midi to Pepinster
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €12–18
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €12–18
- 1st Class
- €18–27
Train from Luxembourg to Trois-Ponts
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €10–15
- 1st Class
- €16–23
Train from Louvain to Verviers-Central
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–15
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €10–15
- 1st Class
- €15–22
Train from Mannheim Hbf to Aachen Hbf
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a week
- Estimated price
- €27–40
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €27–40
- 1st Class
- €40–60
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 54m
- Frequency
- Every 4 hours
- Estimated price
- €19–35
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 3h 44m
- Frequency
- Once daily
- Estimated price
- €40–80
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 19m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 5h 58m
- Frequency
- Every 4 hours
- Estimated price
- €25–40
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Mulhouse Ville to Luxembourg
- Ave. Duration
- 2h 37m
- Frequency
- Twice daily
- Estimated price
- €35–85
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Eindhoven to Heerlen
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €16–50
- Website
- https://www.ns.nl/en
- 2nd Class
- €16–24
- 1st Class
- €30–50
- Phone
- 0800-0232 545
- Website
- arriva.nl
Train from Eindhoven to Heerlen
- Ave. Duration
- 1h 15m
- Frequency
- Once a week
- Estimated price
- €21–23
- Website
- https://www.arriva.nl
- 2nd Class
- €21–23
- Phone
- 0221 13 999 444
- Website
- nationalexpress.de
Train from Duesseldorf Hbf to Aachen Hbf
- Ave. Duration
- 1h 27m
- Frequency
- Every 30 minutes
- Estimated price
- €19–28
- Schedules at
- nationalexpress.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Duesseldorf Hbf to Aachen Hbf
- Ave. Duration
- 1h 27m
- Frequency
- 3 times a day
- Estimated price
- €24–35
- Website
- https://int.bahn.de/en
- Phone
- +49 9126 301 90 70
- fahrgaeste@train-rental.com
- Website
- train-rental.com
Train from Duesseldorf Hbf to Aachen Hbf
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a week
- Schedules at
- train-rental.com
- info@flibco.com
- Website
- flibco.com
Bus from Charleroi Airport to Liège Rue du Plan Inclined
- Ave. Duration
- 1h 5m
- Frequency
- Every 3 hours
- Estimated price
- €15–19
- Website
- https://www.flibco.com/en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Genoa - Via Fanti d'Italia Bus Stop to Mulhouse
- Ave. Duration
- 8h 50m
- Frequency
- 3 times a week
- Estimated price
- €35–55
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h
- Frequency
- 3 times a day
- Estimated price
- €14–40
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Liège Guillemins
- Ave. Duration
- 12h 35m
- Frequency
- 5 times a week
- Estimated price
- €45–110
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Pisa to Spa bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Pisa to Spa train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Spa is 1056 km. It takes approximately 10h 52m to drive from Pisa to Spa.
Book your Pisa to Spa train tickets online with Omio.
There are 1649+ hotels available in Spa.






































































