There are 8 ways to get from Pisa to Sistine Chapel by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Roma Tiburtina (Trenitalia)
best- Take the train from Pisa Centrale to Roma Tiburtinatrain Fa
3h 9m€30–65Bus
cheapest- Take the bus from Pisa to Roma, Autostazione Tiburtinabus N1508 / ...
5h 54m€13–27Drive 324.3 km
- Drive from Pisa to Sistine Chapelcar 324.3 km
3h 46m€50–71Fly from Pisa International Airport
- Fly from Pisa International Airport (PSA) to Fiumicino International Airport (FCO)plane PSA - FCO
5h 3m€60–220Train (Trenitalia)
- Take the train from Pisa Centrale to Roma S. Pietrotrain 4125 / ...
3h 56m€17–60Bus via Pisa Pietrasantina Bus Station
- Take the bus from Pisa Pietrasantina Bus Station to Roma, Autostazione Tiburtinabus MarinoBus 207
7h 9m€17–37Train to Florence Peretola Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
4h 49m€75–224Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane BLQ - FCO
5h 34m€74–281
Pisa to Sistine Chapel by train and foot (Trenitalia)
Questions & Answers
The cheapest way to get from Pisa to Sistine Chapel is to bus which costs €13 - €28 and takes 5h 54m.
The fastest way to get from Pisa to Sistine Chapel is to train via Roma Tiburtina which takes 3h 9m and costs €30 - €70.
No, there is no direct bus from Pisa to Sistine Chapel. However, there are services departing from Pisa and arriving at Cavalleggeri/S. Pietro via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 54m.
Yes, there is a direct train departing from Pisa Centrale and arriving at Roma S. Pietro. Services depart every four hours, and operate every day. The journey takes approximately 3h 39m.
The distance between Pisa and Sistine Chapel is 345 km. The road distance is 324.3 km.
The best way to get from Pisa to Sistine Chapel without a car is to train via Roma Tiburtina which takes 3h 9m and costs €30 - €70.
It takes approximately 3h 9m to get from Pisa to Sistine Chapel, including transfers.
Pisa to Sistine Chapel bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sistine Chapel train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
The best way to get from Pisa to Sistine Chapel is to train via Roma Tiburtina which takes 3h 9m and costs €30 - €70. Alternatively, you can bus, which costs €13 - €28 and takes 5h 54m, you could also fly, which costs €60 - €220 and takes 5h 3m.
What companies run services between Pisa, Italy and Sistine Chapel, Vatican City?
Trenitalia Frecce operates a train from Pisa Centrale to Roma Tiburtina twice daily. Tickets cost €29–65 and the journey takes 2h 9m. Alternatively, FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 4 times a day. Tickets cost €12–21 and the journey takes 4h 45m.
- Website
- ita-airways.com
Flights from Pisa International Airport to Fiumicino International Airport via Bari
- Ave. Duration
- 4h 35m
- When
- Tuesday and Wednesday
- Estimated price
- €60–230
Flights from Florence Peretola Airport to Fiumicino International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €55–160
Flights from Bologna Guglielmo Marconi Airport to Fiumicino International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €45–140
- Website
- ryanair.com
Flights from Pisa International Airport to Fiumicino International Airport via Palermo
- Ave. Duration
- 4h 26m
- When
- Friday and Saturday
- Estimated price
- €60–230
Flights from Pisa International Airport to Fiumicino International Airport via Bari
- Ave. Duration
- 7h 35m
- When
- Sunday
- Estimated price
- €60–230
- Website
- volotea.com
Flights from Pisa International Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 5h 10m
- When
- Saturday
- Estimated price
- €35–190
- Website
- aeroitalia.com
Flights from Pisa International Airport to Fiumicino International Airport via Cagliari
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €60–230
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Roma Tiburtina
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €29–65
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Roma S. Pietro
- Ave. Duration
- 3h 39m
- Frequency
- Every 4 hours
- Estimated price
- €17–60
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Roma S. Pietro
- Ave. Duration
- 3h 21m
- Frequency
- Twice a week
- Estimated price
- €20–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 45m
- Frequency
- 4 times a day
- Estimated price
- €12–21
- Website
- https://www.flixbus.co.uk
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Pisa Pietrasantina Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €16–27
- Website
- https://marinobus.it/en/
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Pisa Pietrasantina Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a week
- Estimated price
- €27–31
- Schedules at
- autolineemoretti.it
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More Questions & Answers
Pisa to Sistine Chapel bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Pisa to Sistine Chapel train services, operated by Trenitalia Frecce, arrive at Roma Tiburtina station.
Yes, the driving distance between Pisa to Sistine Chapel is 324 km. It takes approximately 3h 46m to drive from Pisa to Sistine Chapel.
Book your Pisa to Sistine Chapel train tickets online with Omio.
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