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How to get fromPisa to Sistine Chapelby train (Trenitalia), bus, car, plane, or train

Find Transport to Sistine Chapel

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There are 8 ways to get from Pisa to Sistine Chapel by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Pisa Centrale to Roma S. Pietrotrain train 4135 / ...
    3h 57m
    €30–75
  2. Bus

    cheapest
    1. Take the bus from Pisa to Fiumicino Aeroporto T3bus bus N548
    5h 46m
    €26–55
  3. Drive 324.3 km

    1. Drive from Pisa to Sistine Chapelcar car 324.3 km
    3h 46m
    €52–75
  4. Fly Pisa International Airport to Fiumicino International Airport

    1. Fly from Pisa International Airport (PSA) to Fiumicino International Airport (FCO)plane plane PSA - FCO
    4h 21m
    €49–199
  5. Fly Pisa International Airport to Roma Ciampino Airport

    1. Fly from Pisa International Airport (PSA) to Roma Ciampino Airport (CIA)plane plane PSA - CIA
    4h 30m
    €56–261
  6. Train to Florence Peretola Airport, fly to Fiumicino International Airport

    1. Take the train from Pisa Centrale to Firenze Rifreditrain train
    2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane plane FLR - FCO
    4h 32m
    €73–213
  7. Train, train to Bologna Guglielmo Marconi Airport, fly to Fiumicino International Airport

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane plane BLQ - FCO
    5h 17m
    €62–222
  8. Train to Genoa Cristoforo Colombo Airport, fly to Fiumicino International Airport

    1. Take the train from Pisa Centrale to Genova Brignoletrain train
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane plane GOA - FCO
    5h 45m
    €61–193

Pisa to Sistine Chapel by train and foot (Trenitalia)

Calendar131Weekly Services
Duration3h 57mAverage Duration
Ticket€30Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Sistine Chapel, Vatican City?

Trenitalia operates a train from Pisa Centrale to Roma S. Pietro hourly. Tickets cost €35–65 and the journey takes 3h 39m. Trenitalia Intercity also services this route once daily. Alternatively, FlixBus operates a bus from Pisa to Fiumicino Aeroporto T3 once daily. Tickets cost €23–40 and the journey takes 4h 35m.

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Want to know more about travelling around Vatican City

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