There are 9 ways to get from Pisa to Sistine Chapel by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Roma Tiburtina (Trenitalia)
best- Take the train from Pisa Centrale to Roma Tiburtinatrain Fa / ...
3h€48–80Bus
cheapest- Take the bus from Pisa to Roma, Autostazione Tiburtinabus N1508 / ...
5h 51m€29–50Drive 324.3 km
- Drive from Pisa to Sistine Chapelcar 324.3 km
3h 46m€53–76Fly Pisa International Airport to Fiumicino International Airport
- Fly from Pisa International Airport (PSA) to Fiumicino International Airport (FCO)plane PSA - FCO
4h 13m€59–208Train (Trenitalia)
- Take the train from Pisa Centrale to Roma S. Pietrotrain 4125 / ...
3h 57m€30–65Train to Florence Peretola Airport, fly to Fiumicino International Airport
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
4h 34m€74–220Fly Pisa International Airport to Roma Ciampino Airport
- Fly from Pisa International Airport (PSA) to Roma Ciampino Airport (CIA)plane PSA - CIA
4h 31m€105–304Train, train to Bologna Guglielmo Marconi Airport, fly to Fiumicino International Airport
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane BLQ - FCO
5h 18m€66–258Train to Genoa Cristoforo Colombo Airport, fly to Fiumicino International Airport
- Take the train from Pisa Centrale to Genova Brignoletrain
- Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane GOA - FCO
5h 45m€61–205
Pisa to Sistine Chapel by train and foot (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Pisa to Sistine Chapel is to bus which costs €28 - €50 and takes 5h 51m.
The fastest way to get from Pisa to Sistine Chapel is to train via Roma Tiburtina which takes 3h and costs €45 - €85.
No, there is no direct bus from Pisa to Sistine Chapel. However, there are services departing from Pisa and arriving at Cavalleggeri/S. Pietro via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 51m.
Yes, there is a direct train departing from Pisa Centrale and arriving at Roma S. Pietro. Services depart every two hours, and operate every day. The journey takes approximately 3h 39m.
The distance between Pisa and Sistine Chapel is 345 km. The road distance is 324.3 km.
The best way to get from Pisa to Sistine Chapel without a car is to train via Roma Tiburtina which takes 3h and costs €45 - €85.
It takes approximately 3h to get from Pisa to Sistine Chapel, including transfers.
Pisa to Sistine Chapel bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sistine Chapel train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
The best way to get from Pisa to Sistine Chapel is to train via Roma Tiburtina which takes 3h and costs €45 - €85. Alternatively, you can bus, which costs €28 - €50 and takes 5h 51m, you could also fly, which costs €55 - €210 and takes 4h 13m.
What companies run services between Pisa, Italy and Sistine Chapel, Vatican City?
Trenitalia Frecce operates a train from Pisa Centrale to Roma Tiburtina 5 times a day. Tickets cost €45–80 and the journey takes 2h 9m. Alternatively, FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 3 times a day. Tickets cost €27–45 and the journey takes 4h 45m.
- Website
- ryanair.com
Flights from Pisa International Airport to Fiumicino International Airport via Palermo
- Ave. Duration
- 4h 18m
- When
- Tuesday to Thursday
- Estimated price
- €60–180
Flights from Pisa International Airport to Fiumicino International Airport via Bari
- Ave. Duration
- 4h 25m
- When
- Tuesday
- Estimated price
- €60–180
Flights from Pisa International Airport to Roma Ciampino Airport via Cagliari
- Ave. Duration
- 5h 23m
- When
- Tuesday, Monday, Thursday, and Sunday
- Estimated price
- €100–250
Flights from Pisa International Airport to Roma Ciampino Airport via Charleroi
- Ave. Duration
- 4h 40m
- When
- Sunday
- Estimated price
- €100–250
Flights from Pisa International Airport to Roma Ciampino Airport via Prague
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- €100–250
Flights from Pisa International Airport to Roma Ciampino Airport via Budapest
- Ave. Duration
- 6h 20m
- When
- Thursday and Friday
- Estimated price
- €100–250
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Pisa Centrale to Roma Tiburtina
- Ave. Duration
- 2h 9m
- Frequency
- 5 times a day
- Estimated price
- €45–80
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Pisa Centrale to Genova Brignole
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Pisa to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- €27–45
- Website
- Flixbus
Want to know more about travelling around Vatican City
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Booking & Getting There
Pisa to Sistine Chapel bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Pisa to Sistine Chapel train services, operated by Trenitalia Frecce, arrive at Roma Tiburtina station.
Yes, the driving distance between Pisa to Sistine Chapel is 324 km. It takes approximately 3h 46m to drive from Pisa to Sistine Chapel.
Book your Pisa to Sistine Chapel train tickets online with Omio.
There are 21355+ hotels available in Sistine Chapel.