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How to get fromPisa to Sistine Chapelby train (Trenitalia), bus, car, plane, or train

Find Transport to Sistine Chapel

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There are 10 ways to get from Pisa to Sistine Chapel by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Florence (Trenitalia)

    best
    1. Take the train from Pisa Centrale to Firenze S.M.N.train train Re / ...
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3h 46m
    €39–93
  2. Bus via Fiumicino Aeroporto T3

    cheapest
    1. Take the bus from Pisa to Fiumicino Aeroporto T3bus bus N548
    5h 46m
    €25–53
  3. Drive 324.3 km

    1. Drive from Pisa to Sistine Chapelcar car 324.3 km
    3h 46m
    €51–73
  4. Fly Pisa International Airport to Fiumicino International Airport

    1. Fly from Pisa International Airport (PSA) to Fiumicino International Airport (FCO)plane plane PSA - FCO
    4h 23m
    €50–199
  5. Train (Trenitalia)

    1. Take the train from Pisa Centrale to Roma S. Pietrotrain train 4125 / ...
    3h 57m
    €30–75
  6. Bus

    1. Take the bus from Pisa to Roma - Via Vincenzo Giudicebus bus
    7h 47m
    €34–64
  7. Fly Pisa International Airport to Roma Ciampino Airport

    1. Fly from Pisa International Airport (PSA) to Roma Ciampino Airport (CIA)plane plane PSA - CIA
    4h 29m
    €53–284
  8. Bus to Florence Peretola Airport, fly to Fiumicino International Airport

    1. Take the bus from Pisa International Airport to Florence Airportbus bus
    2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane plane FLR - FCO
    4h 9m
    €75–219
  9. Train, train to Bologna Guglielmo Marconi Airport, fly to Fiumicino International Airport

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane plane BLQ - FCO
    5h 36m
    €62–212
  10. Train to Genoa Cristoforo Colombo Airport, fly to Fiumicino International Airport

    1. Take the train from Pisa Centrale to Genova P.Za Principetrain train
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane plane GOA - FCO
    6h 5m
    €65–225

Pisa to Sistine Chapel by train, subway, and foot (Trenitalia)

Calendar367Weekly Services
Duration3h 46mAverage Duration
Ticket€39Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Sistine Chapel, Vatican City?

You can take a train from Pisa Centrale to Sistine Chapel via Firenze S.M.N., Rome Termini, Termini, and Ottaviano in around 3h 46m. Alternatively, FlixBus operates a bus from Pisa to Fiumicino Aeroporto T3 once daily. Tickets cost €23–40 and the journey takes 4h 35m.

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Want to know more about travelling around Vatican City

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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