There are 8 ways to get from Pisa to Sistine Chapel by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence
best- Take the train from Pisa Centrale to Firenze S.M.N.Re / ...
- Take the train from Florence Santa Maria Novella to Roma Termini8959 / ...
3h 47m€42–80Bus
cheapest- Take the bus from Pisa to Roma, Autostazione TiburtinaN1508 / ...
5h 49m€13–39Drive 324.3 km
- Drive from Pisa to Sistine Chapel324.3 km
3h 43m€51–73Fly from Pisa International Airport
- Fly from Pisa International Airport (PSA) to Fiumicino International Airport (FCO)PSA - FCO
4h 20m€51–209Train
- Take the train from Pisa Centrale to Roma S. Pietro4137 / ...
3h 56m€23–60Bus via Anagnina
- Take the bus from Pisa to Roma - Via Vincenzo Giudice
7h 47m€34–64Train to Florence Peretola Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)FLR - FCO
4h 51m€78–244Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Bologna Centrale
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)BLQ - FCO
5h 34m€74–281
Pisa to Sistine Chapel by train, subway, and foot
Questions & Answers
The cheapest way to get from Pisa to Sistine Chapel is to bus which costs €13 - €40 and takes 5h 49m.
The fastest way to get from Pisa to Sistine Chapel is to drive which takes 3h 43m and costs €50 - €75.
No, there is no direct bus from Pisa to Sistine Chapel. However, there are services departing from Pisa and arriving at Emo via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 49m.
Yes, there is a direct train departing from Pisa Centrale and arriving at Roma S. Pietro. Services depart every four hours, and operate every day. The journey takes approximately 3h 39m.
The distance between Pisa and Sistine Chapel is 344 km. The road distance is 324.3 km.
The best way to get from Pisa to Sistine Chapel without a car is to train via Florence which takes 3h 47m and costs €40 - €80.
It takes approximately 3h 47m to get from Pisa to Sistine Chapel, including transfers.
Pisa to Sistine Chapel bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sistine Chapel train services, operated by Trenitalia S.p.A., depart from Pisa Centrale station.
The best way to get from Pisa to Sistine Chapel is to train via Florence which takes 3h 47m and costs €40 - €80. Alternatively, you can bus, which costs €13 - €40 and takes 5h 49m, you could also fly, which costs €50 - €210 and takes 4h 20m.
What companies run services between Pisa, Italy and Sistine Chapel, Vatican City?
You can take a train from Pisa Centrale to Sistine Chapel via Florence Santa Maria Novella, Rome Termini, Termini, and Ottaviano in around 3h 47m. Alternatively, FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 4 times a day. Tickets cost €12–35 and the journey takes 4h 45m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Fiumicino International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €55–190
Flights from Bologna Guglielmo Marconi Airport to Fiumicino International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €45–140
- Website
- ryanair.com
Flights from Pisa International Airport to Fiumicino International Airport via Bari
- Ave. Duration
- 3h 50m
- When
- Friday
- Estimated price
- €65–230
Flights from Pisa International Airport to Fiumicino International Airport via Palermo
- Ave. Duration
- 4h 33m
- When
- Friday and Saturday
- Estimated price
- €65–230
- Website
- volotea.com
Flights from Pisa International Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 5h 10m
- When
- Saturday
- Estimated price
- €100–230
- Website
- flexflight.dk
Flights from Pisa International Airport to Fiumicino International Airport via Cagliari
- Ave. Duration
- 3h 10m
- When
- Friday and Sunday
- Estimated price
- €65–230
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €16–24
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Roma S. Pietro
- Ave. Duration
- 3h 39m
- Frequency
- Every 4 hours
- Estimated price
- €23–60
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €24–55
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Roma S. Pietro
- Ave. Duration
- 3h 21m
- Frequency
- Twice a week
- Estimated price
- €24–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 45m
- Frequency
- 4 times a day
- Estimated price
- €12–35
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Pisa to Roma - Via Vincenzo Giudice
- Ave. Duration
- 7h
- Frequency
- 3 times a week
- Estimated price
- €30–65
- Schedules at
- autolineemoretti.it
Want to know more about travelling around Vatican City
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More Questions & Answers
Pisa to Sistine Chapel bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Pisa to Sistine Chapel train services, operated by Trenitalia S.p.A., arrive at Roma S. Pietro station.
Yes, the driving distance between Pisa to Sistine Chapel is 324 km. It takes approximately 3h 43m to drive from Pisa to Sistine Chapel.
Book your Pisa to Sistine Chapel train tickets online with Omio.
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