There are 10 ways to get from Pisa to Sistine Chapel by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence (Trenitalia)
best- Take the train from Pisa Centrale to Firenze S.M.N.train Re / ...
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
3h 46m€39–93Bus via Fiumicino Aeroporto T3
cheapest- Take the bus from Pisa to Fiumicino Aeroporto T3bus N548
5h 46m€25–53Drive 324.3 km
- Drive from Pisa to Sistine Chapelcar 324.3 km
3h 46m€51–73Fly Pisa International Airport to Fiumicino International Airport
- Fly from Pisa International Airport (PSA) to Fiumicino International Airport (FCO)plane PSA - FCO
4h 23m€50–199Train (Trenitalia)
- Take the train from Pisa Centrale to Roma S. Pietrotrain 4125 / ...
3h 57m€30–75Bus
- Take the bus from Pisa to Roma - Via Vincenzo Giudicebus
7h 47m€34–64Fly Pisa International Airport to Roma Ciampino Airport
- Fly from Pisa International Airport (PSA) to Roma Ciampino Airport (CIA)plane PSA - CIA
4h 29m€53–284Bus to Florence Peretola Airport, fly to Fiumicino International Airport
- Take the bus from Pisa International Airport to Florence Airportbus
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
4h 9m€75–219Train, train to Bologna Guglielmo Marconi Airport, fly to Fiumicino International Airport
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane BLQ - FCO
5h 36m€62–212Train to Genoa Cristoforo Colombo Airport, fly to Fiumicino International Airport
- Take the train from Pisa Centrale to Genova P.Za Principetrain
- Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane GOA - FCO
6h 5m€65–225
Pisa to Sistine Chapel by train, subway, and foot (Trenitalia)
Questions & Answers
The cheapest way to get from Pisa to Sistine Chapel is to bus via Fiumicino Aeroporto T3 which costs €25 - €55 and takes 5h 46m.
The fastest way to get from Pisa to Sistine Chapel is to train via Florence which takes 3h 46m and costs €35 - €95.
No, there is no direct bus from Pisa to Sistine Chapel. However, there are services departing from Pisa and arriving at Rome Vatican via Fiumicino Aeroporto T3. The journey, including transfers, takes approximately 5h 46m.
Yes, there is a direct train departing from Pisa Centrale and arriving at Roma S. Pietro. Services depart every four hours, and operate every day. The journey takes approximately 3h 39m.
The distance between Pisa and Sistine Chapel is 344 km. The road distance is 324.3 km.
The best way to get from Pisa to Sistine Chapel without a car is to train via Florence which takes 3h 46m and costs €35 - €95.
It takes approximately 3h 46m to get from Pisa to Sistine Chapel, including transfers.
Pisa to Sistine Chapel bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sistine Chapel train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Sistine Chapel is to train via Florence which takes 3h 46m and costs €35 - €95. Alternatively, you can bus via Fiumicino Aeroporto T3, which costs €25 - €55 and takes 5h 46m, you could also fly, which costs €50 - €200 and takes 4h 23m.
What companies run services between Pisa, Italy and Sistine Chapel, Vatican City?
You can take a train from Pisa Centrale to Sistine Chapel via Firenze S.M.N., Rome Termini, Termini, and Ottaviano in around 3h 46m. Alternatively, FlixBus operates a bus from Pisa to Fiumicino Aeroporto T3 once daily. Tickets cost €23–40 and the journey takes 4h 35m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Fiumicino International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- €55–140
Flights from Bologna Guglielmo Marconi Airport to Fiumicino International Airport
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €50–95
Flights from Genoa Cristoforo Colombo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- €45–120
- Website
- ryanair.com
Flights from Pisa International Airport to Fiumicino International Airport via Palermo
- Ave. Duration
- 4h 1m
- When
- Tuesday, Saturday, and Friday
- Estimated price
- €45–170
Flights from Pisa International Airport to Roma Ciampino Airport via Cagliari
- Ave. Duration
- 4h 36m
- When
- Tuesday, Monday, and Thursday
- Estimated price
- €50–600
Flights from Pisa International Airport to Roma Ciampino Airport via Prague
- Ave. Duration
- 4h 55m
- When
- Wednesday
- Estimated price
- €50–260
Flights from Pisa International Airport to Roma Ciampino Airport via Budapest
- Ave. Duration
- 5h 35m
- When
- Thursday, Friday, and Sunday
- Estimated price
- €50–260
- Website
- aeroitalia.com
Flights from Pisa International Airport to Fiumicino International Airport via Cagliari
- Ave. Duration
- 3h 28m
- When
- Thursday, Sunday, and Monday
- Estimated price
- €45–430
Flights from Pisa International Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h 35m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €35–190
Flights from Genoa Cristoforo Colombo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–330
- Website
- flexflight.dk
Flights from Pisa International Airport to Fiumicino International Airport via Cagliari
- Ave. Duration
- 3h 28m
- When
- Thursday, Sunday, and Monday
- Estimated price
- €45–430
Flights from Pisa International Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h 35m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €35–190
Flights from Genoa Cristoforo Colombo Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–330
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €9–16
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 52m
- Frequency
- 4 times a day
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Roma S. Pietro
- Ave. Duration
- 3h 39m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 42m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- €24–50
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €27–60
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Roma S. Pietro
- Ave. Duration
- 3h 21m
- Frequency
- Twice a week
- Estimated price
- €30–75
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 1m
- Frequency
- Every 4 hours
- Estimated price
- €16–40
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 23m
- Frequency
- 3 times a week
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 41 min
- Frequency
- Twice daily
- Estimated price
- €12–24
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Pisa to Fiumicino Aeroporto T3
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- €23–40
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Pisa to Roma - Via Vincenzo Giudice
- Ave. Duration
- 7h
- Frequency
- 3 times a week
- Estimated price
- €30–65
- Schedules at
- autolineemoretti.it
- info@flibco.com
- Website
- flibco.com
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- https://www.flibco.com/en
Want to know more about travelling around Vatican City
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More Questions & Answers
Pisa to Sistine Chapel bus services, operated by FlixBus, arrive at Fiumicino Aeroporto T3 station.
Pisa to Sistine Chapel train services, operated by Trenitalia, arrive at Roma S. Pietro station.
Yes, the driving distance between Pisa to Sistine Chapel is 324 km. It takes approximately 3h 46m to drive from Pisa to Sistine Chapel.
Book your Pisa to Sistine Chapel train tickets online with Omio.
Book your Pisa to Sistine Chapel bus tickets online with Omio.
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