There are 7 ways to get from Pisa to Sicily by plane, train (Trenitalia), bus, car ferry, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pisa International Airport to Palermo Airport
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
2h 22m€63–205Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus N538 / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermobus N597 / ...
19h 34m€34–98Train
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 40m€60–185Car ferry
- Take the car ferry from Livorno to Port of Palermocarferry
20h€55–66Fly Pisa International Airport to Catania–Fontanarossa Airport
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
1h 57m€47–186Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
4h 43m€42–189Bus via Rome
- Take the bus from Pisa Pietrasantina Bus Station to Roma, Autostazione Tiburtinabus MarinoBus 207
- Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus Itabus
20h 49m€48–77
Pisa to Sicily by train
Questions & Answers
The cheapest way to get from Pisa to Sicily is to car ferry which costs €50 - €70 and takes 20h.
The fastest way to get from Pisa to Sicily is to fly which takes 1h 57m and costs €45 - €190.
No, there is no direct bus from Pisa to Sicily. However, there are services departing from Pisa and arriving at Piazza Boiardo via Florence Villa Constanza Bus Station and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 19h 34m.
No, there is no direct train from Pisa to Sicily. However, there are services departing from Pisa Centrale and arriving at Palermo Notarbartolo via Florence Santa Maria Novella, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 16h 40m.
The distance between Pisa and Sicily is 685 km.
The best way to get from Pisa to Sicily without a car is to train which takes 16h 40m and costs €60 - €190.
It takes approximately 2h 22m to get from Pisa to Sicily, including transfers.
Pisa to Sicily bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sicily train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Sicily is to fly which takes 2h 22m and costs €60 - €210. Alternatively, you can train, which costs €60 - €190 and takes 16h 40m, you could also bus, which costs €30 - €100 and takes 19h 34m.
What companies run services between Pisa, Italy and Sicily, Italy?
Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a train from Pisa Centrale to Palermo Notarbartolo via Florence Santa Maria Novella, Roma Termini, and Palermo Centrale in around 16h 40m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €55–200
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €40–170
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- €70–140
- Website
- volotea.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €26–150
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €28–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €27–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- €8–11
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €24–85
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Pisa Pietrasantina Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €16–27
- Website
- https://marinobus.it/en/
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Pisa Pietrasantina Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a week
- Estimated price
- €27–31
- Schedules at
- autolineemoretti.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus
- Ave. Duration
- 13h 15m
- Frequency
- 3 times a week
- Estimated price
- €30–45
- Website
- https://www.itabus.it/en/home
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Car ferry from Livorno to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 3 times a week
- Estimated price
- €50–60
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
How to get from Florence to Rome
Read the travel guide
More Questions & Answers
Pisa to Sicily bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Sicily train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Pisa to Sicily train tickets online with Omio.
There are 5698+ hotels available in Sicily.





























