There are 8 ways to get from Pisa to Sicily by plane, train (Trenitalia), bus, ferry, train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)PSA - PMO
2h 20m€69–200Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Station443 / ...
- Take the bus from Florence Villa Constanza Bus Station to PalermoN597 / ...
20h 13m€45–170Train
- Take the train from Pisa Centrale to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Roma Termini
- Take the train from Roma Termini to Palermo CentraleIc
16h 32m€80–192Ferry
- Take the ferry from Livorno to Port of Palermo
22h 13m€48–101Fly to Catania–Fontanarossa Airport
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)PSA - CTA
1h 57m€55–179Fly to Trapani Airport
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)PSA - TPS
2h 50m€83–233Train, bus
- Take the train from Pisa Centrale to Firenze S.M.N.Re
- Take the bus from Florence Villa Constanza Bus Station to Trapani Imbarco Aliscafo Liberty Lines
- Take the bus from Trapani Imbarco Aliscafo Liberty Lines to Palermo-Via Libertà
22h 39m€67–101Drive, car ferry
- Drive from Pisa to Port of Genoa
- Take the car ferry from Port of Genoa to Port of Palermo
22h 47m€86–168
Pisa to Sicily by train
Questions & Answers
The cheapest way to get from Pisa to Sicily is to ferry which costs €45 - €110 and takes 22h 13m.
The fastest way to get from Pisa to Sicily is to fly which takes 1h 57m and costs €50 - €180.
No, there is no direct bus from Pisa to Sicily. However, there are services departing from Pisa and arriving at Piazza Boiardo via Florence Villa Constanza Bus Station and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 20h 13m.
No, there is no direct train from Pisa to Sicily. However, there are services departing from Pisa Centrale and arriving at Palermo Notarbartolo via Florence Santa Maria Novella, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 16h 32m.
The distance between Pisa and Sicily is 685 km.
The best way to get from Pisa to Sicily without a car is to train which takes 16h 32m and costs €80 - €200.
It takes approximately 2h 20m to get from Pisa to Sicily, including transfers.
Pisa to Sicily bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sicily train services, operated by Trenitalia S.p.A., depart from Pisa Centrale station.
The best way to get from Pisa to Sicily is to fly which takes 2h 20m and costs €65 - €200. Alternatively, you can train, which costs €80 - €200 and takes 16h 32m, you could also bus, which costs €45 - €170 and takes 20h 13m.
What companies run services between Pisa, Italy and Sicily, Italy?
Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) twice daily. Alternatively, you can take a train from Pisa Centrale to Palermo Notarbartolo via Florence Santa Maria Novella, Roma Termini, and Palermo Centrale in around 16h 32m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €65–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €50–170
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 10m
- When
- Sunday
- Estimated price
- €50–170
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, and Saturday
- Estimated price
- €65–260
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €14–24
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €24–55
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 36m
- Frequency
- Once daily
- Estimated price
- €40–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- €8–18
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h 5m
- Frequency
- Twice daily
- Estimated price
- €40–150
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 16h
- Frequency
- Twice a week
- Estimated price
- €35–55
- Schedules at
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Trapani Imbarco Aliscafo Liberty Lines
- Ave. Duration
- 17h 45m
- Frequency
- Twice a week
- Estimated price
- €40–60
- Schedules at
- autoservizisalemi.it
- Phone
- 06 164 160, +39091342525
- info@segesta.it
- Website
- segesta.it
Bus from Trapani Imbarco Aliscafo Liberty Lines to Palermo-Via Libertà
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €11–16
- Schedules at
- segesta.it
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Livorno to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 3 times a week
- Estimated price
- €45–95
- Website
- https://www.grimaldi-lines.com/en/
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–130
- Website
- https://www.gnv.it/en
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More Questions & Answers
Pisa to Sicily bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Sicily train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Book your Pisa to Sicily train tickets online with Omio.
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