There are 11 ways to get from Pisa to Santander by train, plane, train (Trenitalia, Renfe), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Santander Airport
best- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Santander Airport (SDR)FLR - SDR
9h 25m€94–245Bus
cheapest- Take the bus from Pisa to Nice Airport
- Take the bus from Nice Airport to Bilbao
- Take the bus from Bilbao Intermodal to Santander E.A.
25h 31m€81–204Train
- Take the train from Pisa Centrale to Genova P.Za PrincipeFb / ...
- Take the train from Genova P.Za Principe to VentimigliaIc
- Take the train from Ventimiglia to Marseille St Charles
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Take the train from Madrid Chamartín to SantanderAlv / ...
23h 59m€181–355Drive 1,431.7 km
- Drive from Pisa to Santander1,431.7 km
13h 56m€225–325Fly Pisa International Airport to Santander Airport
- Fly from Pisa International Airport (PSA) to Santander Airport (SDR)PSA - SDR
6h 15m€110–220Train, train to Bologna Guglielmo Marconi Airport, fly to Santander Airport
- Take the train from Pisa Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Bologna Centrale
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Santander Airport (SDR)BLQ - SDR
6h 43m€104–312Train to Florence Peretola Airport, fly to Bilbao Airport, bus
- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Bilbao Airport (BIO)FLR - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.
9h 7m€92–273Fly Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport, train
- Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)PSA - MAD
- Take the train from Madrid Chamartín to Santander
7h 55m€110–282Fly Pisa International Airport to Bilbao Airport, bus
- Fly from Pisa International Airport (PSA) to Bilbao Airport (BIO)PSA - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.
7h 6m€87–210Train, bus
- Take the train from Pisa Centrale to VentimigliaIc
- Take the train from Ventimiglia to Nice Saint-AugustinC3
- Take the bus from Nice Airport to Bilbao
- Take the bus from Bilbao Intermodal to Santander E.A.
26h 15m€103–224Bus via Turin
- Take the bus from PISA - Via Pietrasantina Parcheggio to Turin
- Take the bus from Turin Corso Vittorio Emanuele II to Vitoria Gasteiz Central Bus Station
- Take the bus from Vitoria-Gasteiz to Santander E.A.
31h 35m€90–122
Pisa to Santander by train
Questions & Answers
The cheapest way to get from Pisa to Santander is to bus via Turin which costs €90 - €130 and takes 31h 35m.
The fastest way to get from Pisa to Santander is to fly which takes 6h 15m and costs €110 - €220.
No, there is no direct bus from Pisa to Santander. However, there are services departing from Pisa and arriving at Santander E.A. via Nice Airport and Bilbao Intermodal. The journey, including transfers, takes approximately 25h 31m.
No, there is no direct train from Pisa to Santander. However, there are services departing from Pisa Centrale and arriving at Santander via Genova P.Za Principe, Ventimiglia, Marseille St Charles, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 23h 59m.
The distance between Pisa and Santander is 1292 km. The road distance is 1431.7 km.
The best way to get from Pisa to Santander without a car is to train which takes 23h 59m and costs €180 - €360.
It takes approximately 9h 25m to get from Pisa to Santander, including transfers.
Pisa to Santander bus services, operated by FlixBus, depart from Pisa station.
Pisa to Santander train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
The best way to get from Pisa to Santander is to train which takes 23h 59m and costs €180 - €360. Alternatively, you can bus, which costs €80 - €210 and takes 25h 31m, you could also fly, which costs €110 - €220 and takes 6h 15m.
What companies run services between Pisa, Italy and Santander, Spain?
You can take a train from Pisa Centrale to Santander via Genova P.Za Principe, Ventimiglia, Marseille St Charles, Madrid-Puerta de Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 23h 59m. Alternatively, you can take a bus from Pisa to Santander E.A. via Nice Airport, Bilbao, and Bilbao Intermodal in around 25h 31m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- iberia.com
Flights from Florence Peretola Airport to Santander Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 8h 45m
- When
- Every day
- Estimated price
- €70–420
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 55m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–220
Flights from Pisa International Airport to Santander Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 6h 15m
- When
- Wednesday to Sunday
- Estimated price
- €95–200
Flights from Bologna Guglielmo Marconi Airport to Santander Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €85–340
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- €70–210
Flights from Pisa International Airport to Bilbao Airport via Valencia
- Ave. Duration
- 4h 5m
- When
- Friday
- Estimated price
- €75–190
- Website
- vueling.com
Flights from Florence Peretola Airport to Santander Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- €70–220
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 55m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–220
Flights from Pisa International Airport to Santander Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 6h 15m
- When
- Wednesday to Sunday
- Estimated price
- €95–200
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- €70–210
Flights from Pisa International Airport to Bilbao Airport via Valencia
- Ave. Duration
- 4h 5m
- When
- Friday
- Estimated price
- €75–190
- Website
- ryanair.com
Flights from Bologna Guglielmo Marconi Airport to Santander Airport
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €80–160
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–180
- Website
- volotea.com
Flights from Pisa International Airport to Santander Airport via Sevilla
- Ave. Duration
- 12h 15m
- When
- Sunday
- Estimated price
- €95–200
Flights from Florence Peretola Airport to Bilbao Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €45–240
- Website
- airfrance.com
Flights from Florence Peretola Airport to Bilbao Airport via Paris Charles de Gaulle
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- €85–410
- Website
- swiss.com
Flights from Florence Peretola Airport to Bilbao Airport via Zurich
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- €75–390
- Website
- aireuropa.com
Flights from Pisa International Airport to Bilbao Airport via Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 4h
- When
- Monday
- Estimated price
- €75–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €16–24
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 41m
- Frequency
- Every 3 hours
- Estimated price
- €18–21
- Website
- https://www.trenitalia.com/en.html
Train from Ventimiglia to Marseille St Charles
- Ave. Duration
- 3h 57m
- Frequency
- Once a week
- Estimated price
- €15–23
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 54m
- Frequency
- Every 4 hours
- Estimated price
- €19–45
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 19m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €15–21
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 33m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 48m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 20m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- https://www.renfe.com/es/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Ventimiglia to Nice Saint-Augustin
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €6–15
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €6–10
- Rail 1st Class
- €10–15
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Nice Airport
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- €17–40
- Website
- https://www.flixbus.co.uk
Bus from Nice Airport to Bilbao
- Ave. Duration
- 16h 40m
- Frequency
- 3 times a week
- Estimated price
- €55–150
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
Bus from Vitoria-Gasteiz to Santander E.A.
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- €13
- Website
- https://www.alsa.com/en/
- Phone
- 0966 57552
- info@lirosiautoservizi.com
- Website
- lirosiautoserviziorari.com
Bus from PISA - Via Pietrasantina Parcheggio to Turin
- Ave. Duration
- 5h 55m
- Frequency
- 5 times a week
- Estimated price
- €21–24
- Schedules at
- lirosiautoserviziorari.com
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Turin Corso Vittorio Emanuele II to Vitoria Gasteiz Central Bus Station
- Ave. Duration
- 21h
- Frequency
- Once a week
- Estimated price
- €55–85
- Website
- https://union-ivkoni.com/en
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More Questions & Answers
There is no direct flight from Pisa International Airport Airport to Santander Airport Airport. The quickest flight takes 12h 15m and has one stopover.
Pisa to Santander bus services, operated by FlixBus, arrive at Nice Airport station.
Pisa to Santander train services, operated by Trenitalia Frecce, arrive at Genova P.Za Principe station.
Yes, the driving distance between Pisa to Santander is 1432 km. It takes approximately 13h 56m to drive from Pisa to Santander.
Iberia, Volotea and Ryanair offer flights from Pisa International Airport Airport to Santander Airport Airport.
Book your Pisa to Santander train tickets online with Omio.
Book your Pisa to Santander bus tickets online with Omio.
There are 1965+ hotels available in Santander.














































