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How to get fromPisa to Santanderby train, plane, train (Trenitalia, TGV, Renfe), bus or car

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There are 10 ways to get from Pisa to Santander by train, plane, train (Trenitalia, TGV, Renfe), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Santander Airport

    best
    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Santander Airport (SDR)plane plane FLR - SDR
    9h 25m
    €101–255
  2. Bus

    cheapest
    1. Take the bus from Pisa to Nice Airportbus bus
    2. Take the bus from Nice Airport to Bilbaobus bus
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    25h 15m
    €60–201
  3. Train

    1. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    2. Take the train from Nice Ville to Aix En Provence Tgvtrain train Tgv
    3. Take the train from Aix En Provence Tgv to Madrid-Puerta de Atocha-Almudena Grandestrain train
    4. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    24h 4m
    €199–355
  4. Drive 1,431.9 km

    1. Drive from Pisa to Santandercar car 1,431.9 km
    14h 1m
    €225–324
  5. Train, train to Bologna Guglielmo Marconi Airport, fly to Santander Airport

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Take the train from Florence Santa Maria Novella to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Santander Airport (SDR)plane plane BLQ - SDR
    6h 56m
    €94–307
  6. Train to Florence Peretola Airport, fly to Bilbao Airport, bus

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Bilbao Airport (BIO)plane plane FLR - BIO
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    8h 51m
    €80–273
  7. Fly Pisa International Airport to Santander Airport

    1. Fly from Pisa International Airport (PSA) to Santander Airport (SDR)plane plane PSA - SDR
    4h 35m
    €130–220
  8. Fly Pisa International Airport to Bilbao Airport, bus

    1. Fly from Pisa International Airport (PSA) to Bilbao Airport (BIO)plane plane PSA - BIO
    2. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    6h 50m
    €87–203
  9. Train, bus via Nice Airport (NCE)

    1. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    2. Take the train from Ventimiglia to Nice Saint-Augustintrain train C3
    3. Take the bus from Nice Airport to Bilbaobus bus
    4. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    26h 2m
    €83–221
  10. Train, bus

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Padovatrain train Fr
    3. Take the bus from Padova to Santanderbus bus
    29h 27m
    €96–153

Pisa to Santander by train

Calendar7Weekly Trains
Duration24h 4mAverage Duration
Ticket€199Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Santander, Spain?

You can take a train from Pisa Centrale to Santander via Ventimiglia, Nice Ville, Aix En Provence Tgv, Madrid-Puerta de Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 24h 4m. Alternatively, you can take a bus from Pisa to Santander E.A. via Nice Airport, Bilbao, and Bilbao Intermodal in around 25h 15m.

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