There are 10 ways to get from Pisa to Santander by bus, plane, train (Trenitalia, Renfe), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Florence Peretola Airport, fly to Santander Airport
best- Take the bus from Pisa International Airport to Florence Airportbus
- Fly from Florence Peretola Airport (FLR) to Santander Airport (SDR)plane FLR - SDR
8h 16m€102–361Fly Pisa International Airport to Santander Airport
cheapest- Fly from Pisa International Airport (PSA) to Santander Airport (SDR)plane PSA - SDR
5h 45m€70–180Train
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Ventimiglia to Nice Saint-Augustintrain C3
- Take the train from Nice-Saint-Augustin to Marseille-Saint-Charlestrain
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
23h 39m€294–502Bus
- Take the bus from Pisa to Nice Airportbus
- Take the bus from Nice Airport to Bilbaobus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
25h 15m€122–200Drive 1,431.8 km
- Drive from Pisa to Santandercar 1,431.8 km
14h 5m€229–330Train, train to Bologna Guglielmo Marconi Airport, fly to Santander Airport
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Santander Airport (SDR)plane BLQ - SDR
6h 45m€80–295Bus to Florence Peretola Airport, fly to Bilbao Airport, bus
- Take the bus from Pisa International Airport to Florence Airportbus
- Fly from Florence Peretola Airport (FLR) to Bilbao Airport (BIO)plane FLR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 16m€96–257Fly Pisa International Airport to Bilbao Airport, bus
- Fly from Pisa International Airport (PSA) to Bilbao Airport (BIO)plane PSA - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
7h 10m€101–176Train, bus via Nice Airport (NCE)
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Ventimiglia to Nice Saint-Augustintrain C3
- Take the bus from Nice Airport to Bilbaobus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
25h 43m€138–240Train, bus
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Padovatrain Fr
- Take the bus from Padova to Estación de autobuses de Santanderbus
29h 28m€160–225
Pisa to Santander by train
Questions & Answers
The cheapest way to get from Pisa to Santander is to fly and bus which costs €100 - €180 and takes 7h 10m.
The fastest way to get from Pisa to Santander is to fly which takes 5h 45m and costs €70 - €180.
No, there is no direct bus from Pisa to Santander. However, there are services departing from Pisa and arriving at Estación de autobuses de Santander via Nice Airport and Bilbao Intermodal. The journey, including transfers, takes approximately 25h 15m.
No, there is no direct train from Pisa to Santander. However, there are services departing from Pisa Centrale and arriving at Santander via Ventimiglia, Nice-Saint-Augustin, Marseille St Charles, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 23h 39m.
The distance between Pisa and Santander is 1289 km. The road distance is 1431.8 km.
The best way to get from Pisa to Santander without a car is to train which takes 23h 39m and costs €290 - €500.
It takes approximately 8h 16m to get from Pisa to Santander, including transfers.
Pisa to Santander bus services, operated by FlixBus, depart from Pisa station.
Pisa to Santander train services, operated by Trenitalia Intercity, depart from Pisa Centrale station.
The best way to get from Pisa to Santander is to train which takes 23h 39m and costs €290 - €500. Alternatively, you can bus, which costs €120 - €200 and takes 25h 15m, you could also fly, which costs €70 - €180 and takes 5h 45m.
What companies run services between Pisa, Italy and Santander, Spain?
You can take a train from Pisa Centrale to Santander via Ventimiglia, Nice-Saint-Augustin, Marseille-Saint-Charles, Marseille St Charles, Madrid-Puerta De Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 23h 39m. Alternatively, you can take a bus from Pisa to Estación de autobuses de Santander via Nice Airport, Bilbao, and Bilbao Intermodal in around 25h 15m.
- Website
- vueling.com
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 8h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–370
Flights from Florence Peretola Airport to Santander Airport via Madrid
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- €85–380
Flights from Bologna Guglielmo Marconi Airport to Santander Airport via Madrid
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €95–430
Flights from Bologna Guglielmo Marconi Airport to Santander Airport via Barcelona
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- €70–200
Flights from Pisa International Airport to Santander Airport via Madrid
- Ave. Duration
- 10h 50m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €80–350
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h
- When
- Monday, Saturday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–230
Flights from Pisa International Airport to Bilbao Airport via Ibiza
- Ave. Duration
- 5h 20m
- When
- Monday to Friday
- Estimated price
- €55–230
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 36m
- Frequency
- Once daily
- Estimated price
- €30–65
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €10–20
- Website
- Trenitalia Intercity
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 36m
- Frequency
- Once daily
- Estimated price
- €30–65
- Website
- Trenitalia Intercity
- info@flibco.com
- Website
- Flibco
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- Flibco
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- Flibco
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 incredible day trips from Florence by train
Read the travel guide
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
More Questions & Answers
There is no direct flight from Pisa International Airport Airport to Santander Airport Airport. The quickest flight takes 11h 45m and has one stopover.
Pisa to Santander bus services, operated by FlixBus, arrive at Nice Airport station.
Pisa to Santander train services, operated by Trenitalia Intercity, arrive at Ventimiglia station.
Yes, the driving distance between Pisa to Santander is 1432 km. It takes approximately 14h 5m to drive from Pisa to Santander.
Iberia, Volotea and Ryanair offer flights from Pisa International Airport Airport to Santander Airport Airport.
Book your Pisa to Santander train tickets online with Omio.
Book your Pisa to Santander bus tickets online with Omio.
There are 2197+ hotels available in Santander.









