There are 10 ways to get from Pisa to Santander by train, plane, train (Trenitalia, TGV, Renfe), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Santander Airport
best- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Santander Airport (SDR)plane FLR - SDR
9h 25m€101–255Bus
cheapest- Take the bus from Pisa to Nice Airportbus
- Take the bus from Nice Airport to Bilbaobus
- Take the bus from Bilbao Intermodal to Santander E.A.bus
25h 15m€60–201Train
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Nice Ville to Aix En Provence Tgvtrain Tgv
- Take the train from Aix En Provence Tgv to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
24h 4m€199–355Drive 1,431.9 km
- Drive from Pisa to Santandercar 1,431.9 km
14h 1m€225–324Train, train to Bologna Guglielmo Marconi Airport, fly to Santander Airport
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Florence Santa Maria Novella to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Santander Airport (SDR)plane BLQ - SDR
6h 56m€94–307Train to Florence Peretola Airport, fly to Bilbao Airport, bus
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Bilbao Airport (BIO)plane FLR - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.bus
8h 51m€80–273Fly Pisa International Airport to Santander Airport
- Fly from Pisa International Airport (PSA) to Santander Airport (SDR)plane PSA - SDR
4h 35m€130–220Fly Pisa International Airport to Bilbao Airport, bus
- Fly from Pisa International Airport (PSA) to Bilbao Airport (BIO)plane PSA - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.bus
6h 50m€87–203Train, bus via Nice Airport (NCE)
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Ventimiglia to Nice Saint-Augustintrain C3
- Take the bus from Nice Airport to Bilbaobus
- Take the bus from Bilbao Intermodal to Santander E.A.bus
26h 2m€83–221Train, bus
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Padovatrain Fr
- Take the bus from Padova to Santanderbus
29h 27m€96–153
Pisa to Santander by train
Questions & Answers
The cheapest way to get from Pisa to Santander is to bus which costs €60 - €210 and takes 25h 15m.
The fastest way to get from Pisa to Santander is to fly which takes 4h 35m and costs €130 - €220.
No, there is no direct bus from Pisa to Santander. However, there are services departing from Pisa and arriving at Santander E.A. via Nice Airport and Bilbao Intermodal. The journey, including transfers, takes approximately 25h 15m.
No, there is no direct train from Pisa to Santander. However, there are services departing from Pisa Centrale and arriving at Santander via Ventimiglia, Nice Ville, Aix En Provence Tgv, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 24h 4m.
The distance between Pisa and Santander is 1292 km. The road distance is 1431.9 km.
The best way to get from Pisa to Santander without a car is to train which takes 24h 4m and costs €190 - €360.
It takes approximately 9h 25m to get from Pisa to Santander, including transfers.
Pisa to Santander bus services, operated by FlixBus, depart from Pisa station.
Pisa to Santander train services, operated by Trenitalia Intercity, depart from Pisa Centrale station.
The best way to get from Pisa to Santander is to train which takes 24h 4m and costs €190 - €360. Alternatively, you can bus, which costs €60 - €210 and takes 25h 15m, you could also fly, which costs €130 - €220 and takes 4h 35m.
What companies run services between Pisa, Italy and Santander, Spain?
You can take a train from Pisa Centrale to Santander via Ventimiglia, Nice Ville, Aix En Provence Tgv, Madrid-Puerta de Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 24h 4m. Alternatively, you can take a bus from Pisa to Santander E.A. via Nice Airport, Bilbao, and Bilbao Intermodal in around 25h 15m.
- Website
- iberia.com
Flights from Florence Peretola Airport to Santander Airport via Madrid
- Ave. Duration
- 8h 45m
- When
- Every day
- Estimated price
- €90–360
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 55m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–220
Flights from Bologna Guglielmo Marconi Airport to Santander Airport via Madrid
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €85–310
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–220
Flights from Pisa International Airport to Santander Airport via Madrid
- Ave. Duration
- 7h 47m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €75–300
Flights from Pisa International Airport to Bilbao Airport via Valencia
- Ave. Duration
- 4h 5m
- When
- Friday
- Estimated price
- €75–190
- Website
- vueling.com
Flights from Florence Peretola Airport to Santander Airport via Madrid
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- €90–220
Flights from Florence Peretola Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 55m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–220
Flights from Florence Peretola Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–220
Flights from Pisa International Airport to Santander Airport via Madrid
- Ave. Duration
- 7h 1m
- When
- Monday, Thursday, and Friday
- Estimated price
- €75–300
Flights from Pisa International Airport to Bilbao Airport via Valencia
- Ave. Duration
- 4h 5m
- When
- Friday
- Estimated price
- €75–190
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- €70–180
- Website
- ryanair.com
Flights from Bologna Guglielmo Marconi Airport to Santander Airport
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €65–230
- Website
- volotea.com
Flights from Florence Peretola Airport to Bilbao Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €45–190
- Website
- swiss.com
Flights from Florence Peretola Airport to Bilbao Airport via Zurich
- Ave. Duration
- 4h 50m
- When
- Tuesday and Sunday
- Estimated price
- €75–400
- Website
- aireuropa.com
Flights from Pisa International Airport to Bilbao Airport via Madrid
- Ave. Duration
- 4h
- When
- Monday
- Estimated price
- €75–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 36m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Nice Ville to Aix En Provence Tgv
- Ave. Duration
- 2h 59m
- Frequency
- 3 times a day
- Estimated price
- €30–55
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Nice Ville to Aix En Provence Tgv
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €40–90
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €40–60
- Rail 1st Class
- €60–90
Train from Ventimiglia to Nice Saint-Augustin
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €12
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Aix En Provence Tgv to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 34m
- Frequency
- Once daily
- Estimated price
- €90–120
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- €40–90
- Website
- https://www.renfe.com/es/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Padova
- Ave. Duration
- 1h 44m
- Frequency
- Hourly
- Estimated price
- €27–55
- Schedules at
- trenitalia.com
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Nice Airport
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- €17–40
- Website
- https://www.flixbus.co.uk
Bus from Nice Airport to Bilbao
- Ave. Duration
- 16h 40m
- Frequency
- 3 times a week
- Estimated price
- €35–150
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Padova to Santander
- Ave. Duration
- 24h 34m
- Frequency
- 3 times a week
- Estimated price
- €60–75
- Schedules at
- tabitatour.ro
Want to know more about travelling around Spain
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More Questions & Answers
There is no direct flight from Pisa International Airport Airport to Santander Airport Airport. The quickest flight takes 10h 35m and has one stopover.
Pisa to Santander bus services, operated by FlixBus, arrive at Nice Airport station.
Pisa to Santander train services, operated by Trenitalia Intercity, arrive at Ventimiglia station.
Yes, the driving distance between Pisa to Santander is 1432 km. It takes approximately 14h 1m to drive from Pisa to Santander.
Ryanair and Iberia offer flights from Pisa International Airport Airport to Santander Airport Airport.
Book your Pisa to Santander train tickets online with Omio.
Book your Pisa to Santander bus tickets online with Omio.
There are 1935+ hotels available in Santander.












































